Maarouf A. Hoteit, MD
Professor of Clinical Medicine (Gastroenterology)
Director of Multidisciplinary Liver Tumor Clinic, Hospital of the University of Pennsylvania
Medical Director of Liver Transplantation, Hospital of the University of Pennsylvania
Department: Medicine
Contact information
Hospital of the University of Pennsylvania
Liver Transplant Program
3400 Spruce Street
2 Dulles
Philadelphia, PA 19104
Liver Transplant Program
3400 Spruce Street
2 Dulles
Philadelphia, PA 19104
Office: (215) 349-5581
Fax: 215-615-1601
Fax: 215-615-1601
Education:
BS (Biology)
American University of Beirut, 1996.
MD
American University of Beirut, 2000.
Permanent linkBS (Biology)
American University of Beirut, 1996.
MD
American University of Beirut, 2000.
Description of Clinical Expertise
Liver CancerLiver Transplantation
Description of Research Expertise
Liver CancerLiver Transplantation
Selected Publications
Vujkovic M, Kaplan DE, Ghouse J, Loza BL, Brancale J, Lewis A, Zhang DY, Levin MG, Veatch OJ, Johnson JP, Schneider CV, Verma A, Wangensteen KJ, Scorletti E, Gill D, Konkwo C, Garófalo AM, Guare LA, Schwantes-An TW, Abreu MV, Gellert-Kristensen H, Pedersen OB, Erikstrup C, Bundgaard JS, Sørensen E, Ostrowski SR, Bundgaard H, Lee KM, Shaked A, Olthoff KM, Hoteit MA, Speliotes EK, Chen Y, Oliveri A, Yin L, Valenti LV, Malvestiti F, Marchelli D, Miano L, Anstee QM, Daly AK, Cordell HJ, Darlay R, Verweij N, Hindy G, Locke A, Matsuura K, Asrani SK, Testa G, Lotta LA, Jones MB, Dochtermann DR, Norden-Krichmar TM, Teerlink CC, Devineni P, Pyarajan S, Rader DJ, Tanaka Y, Voight BF, Vilarinho S, Bastarache LA, Stender S, Tsao PS; Penn Medicine Biobank; DBDS Genomic Consortium; BioVU Biobank; Michigan Genomics Initiative; Regeneron Genetics Center; Indiana Biobank; All Of Us Research Program; Milano Biobank; LITMUS Consortium; VA Million Veteran Program; Morgan TR, Lynch JA, Chang KM.: Germline Variants Influence Chronic Liver Disease Progression through Distinct Pathways. medRxiv Sep 2025.Bushara O, Kadakia Y, Krupp K, Friedman J, Hoteit MA, Bittermann T, Araji T, Levine MH.: Center Experience Is Associated With Improved Survival in Liver Transplantation for Hilar Cholangiocarcinoma: A Retrospective Study. Transplant Direct 11: e1822, Jun 2025.
Ferrante ND, Hubbard RA, Weinfurtner K, Mezina AI, Newcomb CW, Furth EE, Bhattacharya D, Njei B, Taddei TH, Singal A, Hoteit MA, Park LS, Kaplan D, Lo Re V 3rd.: Validity of Diagnostic Codes and Laboratory Tests to Identify Cholangiocarcinoma and Its Subtypes. Pharmacoepidemiol Drug Saf May 2025.
Kappus MR, Hughes D, Ganger D, Kim Y, Bashir M, Bonn J, Borhani A, Fetzer D, Fischer R, Gabriel H, Guindi M, Hecht E, Hoteit M, Khanna G, Krasuski R, Lewis S, Mavis A, Miller F, Morin C, Schiano T, Schooler G, Shingina A, Sirlin C, Singal A, Taouli B, Tompkins R, Zaidi A, VanWagner L, Yokoo T.: A survey of national practice patterns of hepatocellular carcinoma surveillance for patients with fontan-associated liver disease: A call to action. Liver Transpl Apr 2025.
Singal AG, Yang JD, Jalal PK, Salgia R, Mehta N, Hoteit MA, Kao K, Daher D, El Dahan KS, Hernandez P, Nayak A, Kim N, Pham S, Gamez J, Troost JP, Parikh ND.: Patient-perceived risk of HCC and net benefit of surveillance: A multi-center survey study. Am J Gastroenterol Apr 2025.
Zezulinski D, Hoteit MA, Kaplan DE, Simeone A, Zhan T, Doria C, Ahmed FY, Roberts LR, Block TM, Sayeed A.: Detection of Circulating mRNA Variants in Hepatocellular Carcinoma Patients Using Targeted RNAseq. Liver Cancer Apr 2025.
Hoteit MA, Weinfurtner K.: Recurrent HCC after liver transplantation: Small steps, while awaiting a breakthrough. Liver Transpl 31: 421-422, Apr 2025.
Kim YY, Nyman A, Huang YS, Tomlinson AZ, McRae MP, Everson GT, Vaikunth S, Rosenthal B, Rychik J, Hoteit MA.: Alterations in Liver Perfusion in Adults With Fontan Circulation as Assessed by Dual Cholate Clearance. J Am Heart Assoc Mar 2025.
Rosenthal BE, Hoteit MA, Lluri G, Haeffele C, Daugherty T, Krasuski RA, Serfas JD, de Freitas RA, Porlier A, Lubert AM, Wu FM, Valente AM, Krieger EV, Buber Y, Rodriguez FH 3rd, Gaignard S, Saraf A, Hindes M, Earing MG, Lewis MJ, Rosenbaum MS, Zaidi AN, Hopkins K, Bradley EA, Cedars AM, Ko JL, Franklin WJ, Frederickson A, Ginde S, Grewal J, Nyman A, Min J, Schluger C, Rand E, Hilscher M, Rychik J, Kim YY.: Characteristics and Survival Outcomes of Hepatocellular Carcinoma After the Fontan Operation. JACC Adv 4: 101646, Mar 2025.
Xu E, Tabrizian P, Gutierrez J, Hoteit M, Ghaziani T, Zhou K, Parikh N, Ajmera V, Aby E, Shui A, Marino R, Martin A, Wong C, Kao K, Dave S, Florman S, Yao F, Mehta N.: Downstaging of hepatocellular carcinoma before liver transplantation: Results from a national multicenter prospective cohort study. Hepatology Jan 2025.