Lauren Anton Farrington, PhD

faculty photo
Research Assistant Professor of Obstetrics and Gynecology
Faculty Member, Center for Research on Reproduction and Women's Health (CRRWH), University of Pennsylvania
Faculty Member, Cardiovascular Institute (CVI), Children's Hospital of Philadelphia
Faculty Member, Perinatal Research Center (PRC), Children's Hospital of Philadelphia
Department: Obstetrics and Gynecology

Contact information
1349 Biomedical Research Building II/III
421 Curie Blvd.
Philadelphia, PA 19104
Lab: 2157466865
Education
BS (Biology)
The Pennsylvania State University, 2002.
PhD (Molecular Medicine)
Wake Forest University School of Medicine, 2008.
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Selected Publications

Kholod O, Anton L, Klohonatz K, Ferguson B, Goods BA, Gerson KD: Gardnerella vaginalis induces biosynthesis of higher order polyamines: mechanisms of an optimal host immune response. Pregnancy 2(e70168), Jan 2026 Notes: Presented at Poster Session 3 at the Society for Maternal Fetal Medicine Annual Pregnancy Meeting in Las Vegas, NV.

Anton L, Kholod O, Palmer OG, Klohonatz K, Graskin Z, Leite R, Goods BA, Gerson KD : Menstrual discs for cervicovaginal cellular phenotyping: a novel methodology to define tissue-specific adaptations in pregnancy Pregnancy 2(e70169), Jan 2026 Notes: Presented at Poster Session 4 at the Society for Maternal Fetal Medicine Annual Pregnancy Meeting in Las Vegas, NV.

Klohonatz K, Graskin Z, Leite R, Anton L, Ledyard R, Hacker MR, Burris HH, Gerson KD: Cervical mucin expression is associated with preterm birth: molecular determinants of mucus quality in pregnancy. Pregnancy 2(e70175), Jan 2026 Notes: Presented at Poster Session 2 at the Society for Maternal Fetal Medicine Annual Pregnancy Meeting in Las Vegas, NV.

Kirschen GW, Klohonatz K, Anton L, Gerson KD: Gardnerella vaginalis induces lipid peroxidation and superoxide dismutase activity in the cervicovaginal space. Pregnancy 2(e70168), Jan 2026 Notes: Presented in Poster Session 3 at the Society for Maternal Fetal Medicine Annual Pregnancy meeting in Las Vegas, NV.

Anton L, Cristancho AG, Ferguson B, Ravel J, Elovitz MA: Cervicovaginal microbiome alters transcriptomic and epigenomic signatures across cervicovaginal epithelial barriers. Microbiome 13(1):238, Nov 2025.

Golden TN, Mani S, Linn RL, Leite R, Trigg NA, Wilson A, Anton L, Mainigi M, Conine CC, Kauffman BA, Strauss III JF, Parry S, Simmons RA: Extracellular Vesicles Alter Trophoblast Function in Pregnancies Complicated by COVID-19. J Extracell Vesicles 14(4):e70051, Apr 2025.

Eekhoff JD, Santillan JA, Friday CS, Barnum CE, Weiss SN, Shetye S, Anton L, Elovitz MA, Soslowsky LJ: Fatigue loading and volumetric microscopy demonstrate changes to the mouse cervix throughout and after pregnancy. Connect Tissue Res 29:1-9, Apr 2025.

Kirschen GW, Ferguson B, Anton L, Gerson KD: Spermine and Spermidine Attenuate Glutathione Oxidation by Gardnerella vaginalis: Antioxidant Potential of Vaginal Polyamines. Reproductive Sciences 32(Suppl 1): 16A, Mar 2025 Notes: SRI 72nd Annual Meeting: Scientific Program & Abstracts, Poster #T-004.

Klohonatz K, Ferguson B, Anton L, Gerson KD: Indolelactate Mitigates Anaerobe-Induced Inflammation in the Cervical Epithelium: Potential Role for Lactobacillus crispatus-Derived Lactate Derivatives in Immune Protection. Reproductive Sciences 32(Suppl 1): 36A, Mar 2025 Notes: SRI 72nd Annual Meeting: Scientific Program & Abstracts, Poster #S-008.

Anton L, Klohonatz K, Ferguson B, Gerson KD: Exposure of the Cervical Epithelium to Gardnerella vaginalis and Vaginal Polyamines Alters Macrophage Immune Responses: Evidence for Cellular Crosstalk at the Host-Microbial Interface. Reproductive Sciences 32(Suppl 1): 36A, Mar 2025 Notes: SRI 72nd Annual Meeting: Scientific Program & Abstracts, Poster #S-003.

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Last updated: 06/17/2026
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