Paul J. Mather, MD, FACC,FACP,FAHA,FHFSA,FESC
Professor of Clinical Medicine (Cardiovascular Medicine)
Attending Physician, Hospital of the University of Pennsylvania
Program Lead, Community Outreach, University of Pennsylvania Perelman School of Medicine
Liaison for Advanced Practice Program (Cardiology), Hospital of the University of Pennsylvania and the Perelman School of Medicine
Physician Leader Heart Failure Disease Management, University of Pennsylvania Perelman School of Medicine Heart and Vascular Service Line
Liaison for Hanoi, Vietnam Medical School Initiative, University of Pennsylvania Perelman School of Medicine
Center for Global Health Scholar, University of Pennsylvania
American University of Dubai Project, Penn Center of Global Health
Department: Medicine
Contact information
11-180 PCAM South
34th and Civic Center Blvd
Philadelphia, PA 19104
34th and Civic Center Blvd
Philadelphia, PA 19104
Office: 215-615-0800
Fax: 215-615-0828
Fax: 215-615-0828
Education
BA (Biochemistry)
University of Pennsylvania, 1984.
MD (Medicine)
Temple University School of Medicine, 1988.
Permanent linkBA (Biochemistry)
University of Pennsylvania, 1984.
MD (Medicine)
Temple University School of Medicine, 1988.
Selected Publications
M. Rosen1 M. Cevasco, P. Bravo, M. Galperin-Aizenberg, S. Jha, P. Mather, K. Sidhu: More Than Meets the Scan: A Rare Cause of Apical Perfusion Defect in a Transplanted Heart, Journal of Heart Lung Transplantation, April 2026. Journal of Heart and Lung Transplantation April 2026.Authors: Andrea D’Amato, Federico Ferranti, Claudia Cestiè, Alberto Casasola, Silvia Prosperi, Vincenzo Myftari, Rosanna Germanò, Camilla Segato, Giovanna Manzi, Domenico Filomena, Lucia Ilaria Birtolo, Gaetano Ruocco, Francesco Ciciarello, Alberto Palazzuoli, Massimo Mancone, Paul J Mather, Paul N Casale, Roberto Badagliacca, Francesco Fedele, Carmine Dario Vizza, Paolo Severino * : Manuscript ID: jcdd-4378825 Title: HLM staging and treatment benefit of SGLT2i across heart failure severity Journal of Cardiovascular Development and Disease 30 May 2026 2026.
Dorothea Kehr, Julia Ritterhoff, Manuel Glaser, Lukas Jarosch, Rafael Salazar, Kristin Spaich, Karl Varadi, Jennifer Birkenstock, Michael Egger, Erhe Gao, Walter Koch, Max Sauter, Marc Freichel, Hugo Katus, Norbert Frey, Andreas Jungmann, Cornelius Busch, Paul Mather, Arjang Ruhparwar, Martin Busch, Mirko Völkers, Rebecca Wade, and Patrick Most: S100A1ct: a synthetic peptide derived from S100A1 protein improves cardiac performance and survival in pre-clinical heart failure models. CIRCULATION 151(8): 548-565, Feb 2025 Notes: Epub 2024 Nov.
Ali A, Pilotti J, Pierson N, Mather PJ, : Immune Mediated Necrotizing Myopathy with Non-Ischemic Cardiomyopathy: Exploring Molecular Causes of Heart Failure. Journal of the American College of Cardiology 83(13): 13_Supplement, April 2024.
Paolo Severino, Massimo Mancone, Andrea D’Amato, Marco Valerio Mariani, Silvia Prosperi,Danilo Alunni Fegatelli, Lucia Ilaria Birtolo, Danilo Angotti, Alberto Milanese, Enrico Cerrato,Viviana Maestrini, Carmine Pizzi, Alberto Foà, Annarita Vestri, Alberto Palazzuoli, Carmine Dario Vizza,Paul N. Casale, Paul J. Mather and Francesco Fedele, : Heart failure ‘the cancer of the heart’: the prognostic role of the HLM score, ESC Heart Failure. Wiley, 11(1): 390-399, Feb 2024 Notes: Published online in Wiley Online Library, Epub 2023 Nov.
Olanipekun T, Abe T, Effoe V, Obiora E, Mather P, Echols M, Adedinsewo D: Racial Disparities in the Trends and Outcomes of Cardiogenic Shock Complicating Peripartum Cardiomyopathy. JAMA 5(7): e2220937, Jul 2022.
McCaffrey JA, Dhakal BP, Nathan AS, Ortega-Legaspi J, Fiorilli PN, Mather PJ, Supple GE, : Loss of Right Atrial Pacing Lead Capture Due to Myocardial Infarction Obscuring Diagnosis on Electrogram. JACC Case reports 4(14): 890-894, July 2022.
Norris M, Molina M, Callaghan K, Wang T, Mather P, : Utility of Cardiovascular Magnetic Resonance Imaging in Non-HLA Mediated Cardiac Allograft Dysfunction, ISHLT 2022, USA. ISHLT Journal 41(4): S417, April 2022.
Abe T, Olanipekun T, Igwe J, Khour M, Olukayode B, Musonge-EFFoe J, Vlaery E, Egbuche O, Mather P, Ghali J: Trends, Predictors and Outcomes of Ischemic Stroke Among Patients Hospitalized with Takotsubo Cardiomyopathy. Journal of Stroke and Cerebrovascular Disease. Elsevier, 30(10), October 2021.
Abe T, Olanipekun T, Igwe J, Khour M, Olukayode B, Musonge-EFFoe J, Vlaery E, Egbuche O, Mather P, Ghali J: Trends, Predictors and Outcomes of Ischemic Stroke Among Patients Hospitalized with Takotsubo Cardiomyopathy. Journal of Stroke and Cerebrovascular Disease. 106005, https://doi.org/10.1016/j.jstrokecerebrovasdis.2021.106005, 30(10), October 2021.