Matthew P Kirschen, MD, PhD, MSCE
Associate Professor of Anesthesiology and Critical Care at the Hospital of the University of Pennsylvania and the Children's Hospital of Philadelphia
Director, Pediatric Neurocritical Care Fellowship Program, Children's Hospital of Philadelphia
Director, Pediatric Neurocritical Care, Children's Hospital of Philadelphia
Department: Anesthesiology and Critical Care
Contact information
Children's Hospital of Philadelphia
Department of Anesthesiology and Critical Care Medicine
3401 Civic Center Boulevard
Philadelphia, PA 19104-4399
Department of Anesthesiology and Critical Care Medicine
3401 Civic Center Boulevard
Philadelphia, PA 19104-4399
Office: 215-590-7430
Email:
kirschenm@chop.edu
kirschenm@chop.edu
Education:
BS (Neuroscience)
Brandeis University , 2000.
PhD (Neuroscience)
Stanford University School of Medicine , 2006.
MD (Medicine)
Stanford University School of Medicine, 2007.
MSCE (Clinical Epidemiology)
University of Pennsylvania, 2025.
Permanent linkBS (Neuroscience)
Brandeis University , 2000.
PhD (Neuroscience)
Stanford University School of Medicine , 2006.
MD (Medicine)
Stanford University School of Medicine, 2007.
MSCE (Clinical Epidemiology)
University of Pennsylvania, 2025.
Selected Publications
Andrist E, Kiragu A, Kirschen MP, Agarwal K, Pope TM, Vercler CJ, Saylor KM, Flori HR, Carroll CL; Society of Critical Care Medicine Contestation of Pediatric Brain Death Task Force: Brain Death Contestation: A Scoping Review of Occurrences and Management. Critical Care Medicine December 2025 Notes: Online ahead of print.Montag E, Kirschen MP, Nathanson P, Morrison W, Fieldston E, Walter JK: Prioritization of Ethical Themes When Surrogates Object to Technology Removal After Brain Death Determination. Neurocrit Care 43(3), December 2025 Notes: Epub 2025 Oct 8.
Lewis A, Russell JA, Bonnie RJ, Epstein LG, Greer DM, Rubin MA, Kirschen MP; Ethics, Law, and Humanities Committee (a joint committee of the American Academy of Neurology [AAN], American Neurological Association [ANA], and Child Neurology Society [CNS]): Brain Death/Death by Neurologic Criteria Guidance on Communication, Objections, Pregnancy, and Public Trust. Neurology 105(10): e214334, November 2025 Notes: Epub 2025 Nov 4.
Ullman NL, Reeder RW, Topjian A, Morgan RW, Berg RA, Nadkarni VM, Palmer CA, Sutton RM, Press CA, Kirschen MP; ICU-RESUS, CPCCRN Investigators: Severe intracranial hemorrhage or ischemia associated with unfavorable outcomes after pediatric in-hospital cardiac arrest. Resuscitation November 2025 Notes: Online ahead of print.
Silva LEV, Chen CC, Press CA, Graham K, Shi L, Abend NS, Morgan RW, Topjian A, Tsui FR, Kirschen MP: Pediatric cardiac arrest outcome prediction using data-driven machine learning of early quantitative electroencephalogram (qEEG) features. Resuscitation 216, November 2025 Notes: Epub 2025 Oct 8.
Fischer D and Kirschen MP: Brain Death Testing. Traumacast November 2025 Notes: https://www.east.org/education-resources/traumacasts/detail/2321/brain-death-testing.
Donoghue E, Vossough A, Manteghinejad A, Graham K, Morgan RW, Nadkarni V, Diaz-Arrastia R, Berg RA, Topjian A, Kirschen MP: Association between hypoxic-ischemic brain injury on early head CT imaging and neurologic outcome after pediatric cardiac arrest. American Heart Association/Resuscitation Science Symposium November 2025 Notes: Poster presentation at the American Heart Association/Resuscitation Science Symposium, New Orleans, November 2025.
McSherry ML, Kathryn K, Woods-Hill CZ, Herrmann JR, Kirschen MP, Fowler JC, Gardner MM, Morgan RW, Sutton RM, Topjian A: Timing and mode of death after pediatric in- and out-of-hospital cardiac arrest: a single center retrospective study. Resuscitation 217, November 2025 Notes: Online ahead of print.
Silva, LEV; Gaudio, HA; Padmanabhan, V; Forti, RM; Shi, L; Mason, M; Sueishi, T; Kirschen, MP; Baker, WB; Kilbaugh, TJ; Morgan, RW; Tsui, FR; Ko, TS: Machine Learning-Based Return of Spontaneous Circulation Prediction During Cardiopulmonary Resuscitation in a Swine Model of Cardiac Arrest: Effect of Data Resolution and Multimodal Physiological Waveforms. Critical Care Medicine 54, November 2025 Notes: Online Ahead of Print.
Rubin MA, Kirschen MP: The physiology of dying. Nature Medicine 31(10): 3256-3257, October 2025.