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Matthew P Kirschen, MD, PhD, MSCE
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Associate Professor of Anesthesiology and Critical Care at the Hospital of the University of Pennsylvania and the Children's Hospital of Philadelphia
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Director, Pediatric Neurocritical Care Fellowship Program, Children's Hospital of Philadelphia
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Director, Pediatric Neurocritical Care, Children's Hospital of Philadelphia
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Department: Anesthesiology and Critical Care
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Contact information
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Children's Hospital of Philadelphia
3f Department of Anesthesiology and Critical Care Medicine
43 3401 Civic Center Boulevard
Philadelphia, PA 19104-4399
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3f Department of Anesthesiology and Critical Care Medicine
43 3401 Civic Center Boulevard
Philadelphia, PA 19104-4399
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Office: 215-590-7430
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Email:
kirschenm@chop.edu
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kirschenm@chop.edu
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Education:
21 7 BS 19 (Neuroscience) c
2d Brandeis University , 2000.
21 8 PhD 19 (Neuroscience) c
40 Stanford University School of Medicine , 2006.
21 7 MD 15 (Medicine) c
3f Stanford University School of Medicine, 2007.
21 9 MSCE 22 (Clinical Epidemiology) c
33 University of Pennsylvania, 2025.
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Permanent link21 7 BS 19 (Neuroscience) c
2d Brandeis University , 2000.
21 8 PhD 19 (Neuroscience) c
40 Stanford University School of Medicine , 2006.
21 7 MD 15 (Medicine) c
3f Stanford University School of Medicine, 2007.
21 9 MSCE 22 (Clinical Epidemiology) c
33 University of Pennsylvania, 2025.
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13b Montag E, Kirschen MP, Nathanson P, Morrison W, Fieldston E, Walter JK: Prioritization of Ethical Themes When Surrogates Object to Technology Removal After Brain Death Determination. Neurocrit Care 43(3), December 2025 Notes: Epub 2025 Oct 8.
1ac Lewis A, Russell JA, Bonnie RJ, Epstein LG, Greer DM, Rubin MA, Kirschen MP; Ethics, Law, and Humanities Committee (a joint committee of the American Academy of Neurology [AAN], American Neurological Association [ANA], and Child Neurology Society [CNS]): Brain Death/Death by Neurologic Criteria Guidance on Communication, Objections, Pregnancy, and Public Trust. Neurology 4c 105(10): e214334, November 2025 Notes: Epub 2025 Nov 4.
18e Ullman NL, Reeder RW, Topjian A, Morgan RW, Berg RA, Nadkarni VM, Palmer CA, Sutton RM, Press CA, Kirschen MP; ICU-RESUS, CPCCRN Investigators: Severe intracranial hemorrhage or ischemia associated with unfavorable outcomes after pediatric in-hospital cardiac arrest. Resuscitation November 2025 Notes: Online ahead of print.
171 Silva LEV, Chen CC, Press CA, Graham K, Shi L, Abend NS, Morgan RW, Topjian A, Tsui FR, Kirschen MP: Pediatric cardiac arrest outcome prediction using data-driven machine learning of early quantitative electroencephalogram (qEEG) features. Resuscitation 216, November 2025 Notes: Epub 2025 Oct 8.
ee Fischer D and Kirschen MP: Brain Death Testing. Traumacast November 2025 Notes: https://www.east.org/education-resources/traumacasts/detail/2321/brain-death-testing.
20a Donoghue E, Vossough A, Manteghinejad A, Graham K, Morgan RW, Nadkarni V, Diaz-Arrastia R, Berg RA, Topjian A, Kirschen MP: Association between hypoxic-ischemic brain injury on early head CT imaging and neurologic outcome after pediatric cardiac arrest. American Heart Association/Resuscitation Science Symposium November 2025 Notes: Poster presentation at the American Heart Association/Resuscitation Science Symposium, New Orleans, November 2025.
176 McSherry ML, Kathryn K, Woods-Hill CZ, Herrmann JR, Kirschen MP, Fowler JC, Gardner MM, Morgan RW, Sutton RM, Topjian A: Timing and mode of death after pediatric in- and out-of-hospital cardiac arrest: a single center retrospective study. Resuscitation 217, November 2025 Notes: Online ahead of print.
f5 Silva, LEV; Gaudio, HA; Padmanabhan, V; Forti, RM; Shi, L; Mason, M; Sueishi, T; Kirschen, MP; Baker, WB; Kilbaugh, TJ; Morgan, RW; Tsui, FR; Ko, TS: Machine Learning-Based Return of Spontaneous 2f Circulation Prediction During Cardiopulmonary 2b Resuscitation in a Swine Model of Cardiac 32 Arrest: Effect of Data Resolution and Multimodal 78 Physiological Waveforms. Critical Care Medicine 54, November 2025 Notes: Online Ahead of Print.
a9 Rubin MA, Kirschen MP: The physiology of dying. Nature Medicine 31(10): 3256-3257, October 2025.
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Selected Publications
18c Andrist E, Kiragu A, Kirschen MP, Agarwal K, Pope TM, Vercler CJ, Saylor KM, Flori HR, Carroll CL; Society of Critical Care Medicine Contestation of Pediatric Brain Death Task Force: Brain Death Contestation: A Scoping Review of Occurrences and Management. Critical Care Medicine December 2025 Notes: Online ahead of print.13b Montag E, Kirschen MP, Nathanson P, Morrison W, Fieldston E, Walter JK: Prioritization of Ethical Themes When Surrogates Object to Technology Removal After Brain Death Determination. Neurocrit Care 43(3), December 2025 Notes: Epub 2025 Oct 8.
1ac Lewis A, Russell JA, Bonnie RJ, Epstein LG, Greer DM, Rubin MA, Kirschen MP; Ethics, Law, and Humanities Committee (a joint committee of the American Academy of Neurology [AAN], American Neurological Association [ANA], and Child Neurology Society [CNS]): Brain Death/Death by Neurologic Criteria Guidance on Communication, Objections, Pregnancy, and Public Trust. Neurology 4c 105(10): e214334, November 2025 Notes: Epub 2025 Nov 4.
18e Ullman NL, Reeder RW, Topjian A, Morgan RW, Berg RA, Nadkarni VM, Palmer CA, Sutton RM, Press CA, Kirschen MP; ICU-RESUS, CPCCRN Investigators: Severe intracranial hemorrhage or ischemia associated with unfavorable outcomes after pediatric in-hospital cardiac arrest. Resuscitation November 2025 Notes: Online ahead of print.
171 Silva LEV, Chen CC, Press CA, Graham K, Shi L, Abend NS, Morgan RW, Topjian A, Tsui FR, Kirschen MP: Pediatric cardiac arrest outcome prediction using data-driven machine learning of early quantitative electroencephalogram (qEEG) features. Resuscitation 216, November 2025 Notes: Epub 2025 Oct 8.
ee Fischer D and Kirschen MP: Brain Death Testing. Traumacast November 2025 Notes: https://www.east.org/education-resources/traumacasts/detail/2321/brain-death-testing.
20a Donoghue E, Vossough A, Manteghinejad A, Graham K, Morgan RW, Nadkarni V, Diaz-Arrastia R, Berg RA, Topjian A, Kirschen MP: Association between hypoxic-ischemic brain injury on early head CT imaging and neurologic outcome after pediatric cardiac arrest. American Heart Association/Resuscitation Science Symposium November 2025 Notes: Poster presentation at the American Heart Association/Resuscitation Science Symposium, New Orleans, November 2025.
176 McSherry ML, Kathryn K, Woods-Hill CZ, Herrmann JR, Kirschen MP, Fowler JC, Gardner MM, Morgan RW, Sutton RM, Topjian A: Timing and mode of death after pediatric in- and out-of-hospital cardiac arrest: a single center retrospective study. Resuscitation 217, November 2025 Notes: Online ahead of print.
f5 Silva, LEV; Gaudio, HA; Padmanabhan, V; Forti, RM; Shi, L; Mason, M; Sueishi, T; Kirschen, MP; Baker, WB; Kilbaugh, TJ; Morgan, RW; Tsui, FR; Ko, TS: Machine Learning-Based Return of Spontaneous 2f Circulation Prediction During Cardiopulmonary 2b Resuscitation in a Swine Model of Cardiac 32 Arrest: Effect of Data Resolution and Multimodal 78 Physiological Waveforms. Critical Care Medicine 54, November 2025 Notes: Online Ahead of Print.
a9 Rubin MA, Kirschen MP: The physiology of dying. Nature Medicine 31(10): 3256-3257, October 2025.
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