Matthew P Kirschen, MD, PhD, MSCE

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Associate Professor of Anesthesiology and Critical Care at the Hospital of the University of Pennsylvania and the Children's Hospital of Philadelphia
Director, Pediatric Neurocritical Care Fellowship Program, Children's Hospital of Philadelphia
Director, Pediatric Neurocritical Care, Children's Hospital of Philadelphia
Department: Anesthesiology and Critical Care

Contact information
Children's Hospital of Philadelphia
Department of Anesthesiology and Critical Care Medicine
3401 Civic Center Boulevard
Philadelphia, PA 19104-4399
Office: 215-590-7430
Education:
BS (Neuroscience)
Brandeis University , 2000.
PhD (Neuroscience)
Stanford University School of Medicine , 2006.
MD (Medicine)
Stanford University School of Medicine, 2007.
MSCE (Clinical Epidemiology)
University of Pennsylvania, 2025.
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Selected Publications

Siddique H, Abulhasan Y, Gomez M, Randhawa A, Kirschen M, Varelas P, Shutter L: Impact of a Brain Death Workshop on the Knowledge of Attendees. Poster Presentation at American Academy of Neurology Annual Meeting, Chicago, IL April 2026.

Dhruva N, Harrison D, Ford J, Greer D, Wahlster S, Chhabra N, Lewis A, Shutter L, Rubin M, Varelas P, Busl K, Kirschen M, Nakagawa T, Vespa P, Chang C, Bauer D, Maciel C, Souter M, Goldenberg F, Francoeur C, Bleck T, Sung G, Nelson S, Koffman L, Marcolini E, Galvagno S, O'hana Nobleza C, Fahy B, Rocha Ferreria da Silva I, Rabinstein A, Kumar A, Bonomo J, Hemphill C, Nanchal R, Dengler B, Morris N, on behalf of the Simulation-based mastery learning to assess and Ensure COmpetency in death by Neurologic criteria Determination (SECOND) Study Group.: Simulations and Brain Death: A Novel Approach to Evaluating Competency. American Academy of Neurology April 2026.

Wolfe AHJ, Mcllroy M, Flori H, Sederstrom N, Society of Critical Care Medicine Contestation of Brain Death Taskforce: Discussing Death by Neurologic Criteria in Pediatrics: Opportunities and Challenges for Families and Clinicians. Pediatric Critical Care Medicine April 2026 Notes: Online ahead of print.

Bach AM, Walsh K, Cooper D, Fung F, Press CA, Gupta A, Vossough A, Kirschen MP, Topjian AA, Abend NS.: Post-Anoxic Myoclonic Seizures after Pediatric Cardiac Arrest: Characteristics and Patient Outcomes. Poster Presentation at The Beatrice Nicoletti CHOP Resuscitation Science Center and Global Resuscitation Alliance Conference, Philadelphia, Pennsylvania. March 2026.

Shepard LN, Napolitano N, Dominick C, Nickel AJ, Shults J, McGovern EL, Bruins BB, O'Halloran A, Huh J, Topjian A, Kirschen MP, Morgan RW, Sutton RM, Nadkarni VM, Nishisaki A: Quality of Bag-Mask Ventilation for Children Before Intubation: Single-Center PICU Pilot Observational Study, 2019-2022. Pediatric Critical Care Medicine March 2026 Notes: Online ahead of print.

Lui R, Nadkarni VM, Berg RA, Morgan RW, Topjian AA, Kirschen MP: Association of Hypotension Burden Calculated from Intermittently Documented Blood Pressures and Outcome After Pediatric Cardiac Arrest. Poster Presentation at Society of Critical Care Medicine (SCCM) Critical Care Congress, Chicago, IL March 2026.

Hamad MA, Nishisaki A, Shults J, Napolitano N, Nickel A, Hyde L, Topjian A, Kirschen M, Huh J, Bruins BB, O'Halloran A, McGovern EL, Nadkarni V, Shepard LN: Lung Compliance Immediately After Endotracheal Intubation in the Pediatric ICU. Poster Presentation at Society of Critical Care Medicine (SCCM) Critical Care Congress, Chicago, IL March 2026.

Kirschen NP: Association Between Hypoxic-Ischemic Brain Injury on Early Head CT Imaging and Neurologic Outcome After Pediatric Cardiac Arrest. Poster Presentation at The Beatrice Nicoletti CHOP Resuscitation Science Center and Global Resuscitation Alliance Conference March 2026.

Silva LEV, Gaudio HA, Padmanabhan V, Forti RM, Shi L, Mason M, Sueishi T, Kirschen MP, Baker WB, Kilbaugh TJ, Morgan RW, Tsui FR, Ko TS: Machine Learning-Based Return of Spontaneous Circulation Prediction During Cardiopulmonary Resuscitation in a Swine Model of Cardiac Arrest: Effect of Data Resolution and Multimodal Physiological Waveforms. Critical Care Medicine 54(2): 257–269, February 2026.

Silva LEV, Balcarcel D, Ko TS, Morgan RW, Berg RA, Topjian A, Tsui FR, Kirschen MP: Prediction of neurological outcome after pediatric cardiac arrest using heart rate variability and machine learning. Resuscitation 219: 110961, February 2026 Notes: Epub 2026 Jan 5.

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Last updated: 05/10/2026
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