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Matthew P Kirschen, MD, PhD, MSCE
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Associate Professor of Anesthesiology and Critical Care at the Hospital of the University of Pennsylvania and the Children's Hospital of Philadelphia
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Director, Pediatric Neurocritical Care Fellowship Program, Children's Hospital of Philadelphia
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Director, Pediatric Neurocritical Care, Children's Hospital of Philadelphia
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Department: Anesthesiology and Critical Care
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Contact information
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Children's Hospital of Philadelphia
3f Department of Anesthesiology and Critical Care Medicine
43 3401 Civic Center Boulevard
Philadelphia, PA 19104-4399
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3f Department of Anesthesiology and Critical Care Medicine
43 3401 Civic Center Boulevard
Philadelphia, PA 19104-4399
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Office: 215-590-7430
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Email:
kirschenm@chop.edu
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kirschenm@chop.edu
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Education:
21 7 BS 19 (Neuroscience) c
2d Brandeis University , 2000.
21 8 PhD 19 (Neuroscience) c
40 Stanford University School of Medicine , 2006.
21 7 MD 15 (Medicine) c
3f Stanford University School of Medicine, 2007.
21 9 MSCE 22 (Clinical Epidemiology) c
33 University of Pennsylvania, 2025.
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Permanent link21 7 BS 19 (Neuroscience) c
2d Brandeis University , 2000.
21 8 PhD 19 (Neuroscience) c
40 Stanford University School of Medicine , 2006.
21 7 MD 15 (Medicine) c
3f Stanford University School of Medicine, 2007.
21 9 MSCE 22 (Clinical Epidemiology) c
33 University of Pennsylvania, 2025.
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162 Loaec M, Vossough A, Francoeur C, Graham K, Morgan RW, Topjian AA, Kirschen MP: Spinal cord ischemia following pediatric cardiac arrest: An unexplored complication of hypoxic ischemic injury. Journal of Clinical Neuroscience 147: 111916, February 2026 Notes: Online ahead of print.
152 Silva LEV, Balcarcel D, Ko TS, Morgan RW, Berg RA, Topjian A, Tsui FR, Kirschen MP: Prediction of neurological outcome after pediatric cardiac arrest using heart rate variability and machine learning. Resuscitation 219: 110961, February 2026 Notes: Epub 2026 Jan 5.
11c Steinberg A, Annoni F, Hayashida K, Hutton J, Kirschen MP, Morgan RW: Wolf Creek XVIII Part 8: Wolf Creek Innovator in Cardiac Arrest and Resuscitation Science Award. Resuscitation Plus 28: 101230, January 2026.
19a Andrist E, Kiragu A, Kirschen MP, Agarwal K, Pope TM, Vercler CJ, Saylor KM, Flori HR, Carroll CL; Society of Critical Care Medicine Contestation of Pediatric Brain Death Task Force: Brain Death Contestation: A Scoping Review of Its Incidence and Management. Critical Care Medicine 54(1): 154–162, January 2026 Notes: Epub 2025 Nov 27.
16c Mazzio EL, Catenaccio E, Liu R, Vossough A, Abend NS, Alcamo A, Huh JW, Lang SS, Berg RA, Topjian AA, Press C, Kirschen MP: Association of EEG Response to Hypertonic Saline and Neurologic Outcomes in Pediatric Acute Brain Injury. Neurocritical Care January 2026 Notes: Online ahead of print.
194 Ullman NL, Reeder RW, Topjian A, Morgan RW, Berg RA, Nadkarni VM, Palmer CA, Sutton RM, Press CA, Kirschen MP; ICU-RESUS, CPCCRN Investigators: Severe intracranial hemorrhage or ischemia associated with unfavorable outcomes after pediatric in-hospital cardiac arrest. Resuscitation 218: 110886, January 2026 Notes: Epub 2025 Nov 7.
e8 Kirschen MA, Topjian A, Berg R: Author response: NIRS illuminates, but MAPopt should guide post-cardiac arrest care. Resuscitation 217: 110849, December 2025.
14a Montag E, Kirschen MP, Nathanson P, Morrison W, Fieldston E, Walter JK: Prioritization of Ethical Themes When Surrogates Object to Technology Removal After Brain Death Determination. Neurocritical Care 43(3): 727–735, December 2025 Notes: Epub 2025 Oct 8.
18c Andrist E, Kiragu A, Kirschen MP, Agarwal K, Pope TM, Vercler CJ, Saylor KM, Flori HR, Carroll CL; Society of Critical Care Medicine Contestation of Pediatric Brain Death Task Force: Brain Death Contestation: A Scoping Review of Occurrences and Management. Critical Care Medicine December 2025 Notes: Online ahead of print.
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Selected Publications
e8 Silva LEV, Gaudio HA, Padmanabhan V, Forti RM, Shi L, Mason M, Sueishi T, Kirschen MP, Baker WB, Kilbaugh TJ, Morgan RW, Tsui FR, Ko TS: Machine Learning-Based Return of Spontaneous 2f Circulation Prediction During Cardiopulmonary 2b Resuscitation in a Swine Model of Cardiac 32 Arrest: Effect of Data Resolution and Multimodal 69 Physiological Waveforms. Critical Care Medicine 54(2): 257–269, February 2026.162 Loaec M, Vossough A, Francoeur C, Graham K, Morgan RW, Topjian AA, Kirschen MP: Spinal cord ischemia following pediatric cardiac arrest: An unexplored complication of hypoxic ischemic injury. Journal of Clinical Neuroscience 147: 111916, February 2026 Notes: Online ahead of print.
152 Silva LEV, Balcarcel D, Ko TS, Morgan RW, Berg RA, Topjian A, Tsui FR, Kirschen MP: Prediction of neurological outcome after pediatric cardiac arrest using heart rate variability and machine learning. Resuscitation 219: 110961, February 2026 Notes: Epub 2026 Jan 5.
11c Steinberg A, Annoni F, Hayashida K, Hutton J, Kirschen MP, Morgan RW: Wolf Creek XVIII Part 8: Wolf Creek Innovator in Cardiac Arrest and Resuscitation Science Award. Resuscitation Plus 28: 101230, January 2026.
19a Andrist E, Kiragu A, Kirschen MP, Agarwal K, Pope TM, Vercler CJ, Saylor KM, Flori HR, Carroll CL; Society of Critical Care Medicine Contestation of Pediatric Brain Death Task Force: Brain Death Contestation: A Scoping Review of Its Incidence and Management. Critical Care Medicine 54(1): 154–162, January 2026 Notes: Epub 2025 Nov 27.
16c Mazzio EL, Catenaccio E, Liu R, Vossough A, Abend NS, Alcamo A, Huh JW, Lang SS, Berg RA, Topjian AA, Press C, Kirschen MP: Association of EEG Response to Hypertonic Saline and Neurologic Outcomes in Pediatric Acute Brain Injury. Neurocritical Care January 2026 Notes: Online ahead of print.
194 Ullman NL, Reeder RW, Topjian A, Morgan RW, Berg RA, Nadkarni VM, Palmer CA, Sutton RM, Press CA, Kirschen MP; ICU-RESUS, CPCCRN Investigators: Severe intracranial hemorrhage or ischemia associated with unfavorable outcomes after pediatric in-hospital cardiac arrest. Resuscitation 218: 110886, January 2026 Notes: Epub 2025 Nov 7.
e8 Kirschen MA, Topjian A, Berg R: Author response: NIRS illuminates, but MAPopt should guide post-cardiac arrest care. Resuscitation 217: 110849, December 2025.
14a Montag E, Kirschen MP, Nathanson P, Morrison W, Fieldston E, Walter JK: Prioritization of Ethical Themes When Surrogates Object to Technology Removal After Brain Death Determination. Neurocritical Care 43(3): 727–735, December 2025 Notes: Epub 2025 Oct 8.
18c Andrist E, Kiragu A, Kirschen MP, Agarwal K, Pope TM, Vercler CJ, Saylor KM, Flori HR, Carroll CL; Society of Critical Care Medicine Contestation of Pediatric Brain Death Task Force: Brain Death Contestation: A Scoping Review of Occurrences and Management. Critical Care Medicine December 2025 Notes: Online ahead of print.
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