Lindsay Kathryne Festa, PhD
Postdoctoral Researcher of Microbiology
Research Associate, University of Pennsylvania School of Dental Medicine & The Children's Hospital of Philadelphia
Department: Microbiology
Contact information
3501 Civic Center Blvd Philadelphia, PA 19104
Philadelphia, PA 19145
Philadelphia, PA 19145
Email:
festal@upenn.edu
festal@upenn.edu
Education:
BA (Psychology)
Haverford College, 2009.
MS (Pharmacology)
Thomas Jefferson University, 2013.
PhD (Pharmacology & Physiology)
Drexel University College of Medicine, 2018.
Permanent linkBA (Psychology)
Haverford College, 2009.
MS (Pharmacology)
Thomas Jefferson University, 2013.
PhD (Pharmacology & Physiology)
Drexel University College of Medicine, 2018.
Selected Publications
Festa LK, Jordan-Sciuttto KL, Grinspan JB: Neuroinflammation: an oligodendrocentric view. Glia 73(6): 1113-1129, June 2025.Ho C, Luchetta J, Nash B, Festa L, Johnson J, Sacan A, Jackson J, Sanz-Clemente A, Brandimarti R, Meucci O: CXCL12 engages cortical inhibitory neurons to enhance dendritic spine plasticity and structured network activity. Journal of Neuroscience 45(24): e2213242025, June 2025.
Long CC, Festa LK, Cruz-Berrios M, Johnson T, Mitchell CH, Grinspan JB, Jordan-Sciutto KL: Acidic nanoparticles prevent pre-exposure prophylaxis (PrEP)-induced oligodendrocyte impairments through lysosome reacidification in models of adolescence. Glia 2025.
Festa LK, Fandino Pachon N, Chen SJ, Anderson RN, Sciutto AL, Grinspan JB, Jordan-Sciutto KL: The lysosomal cation channel TRPML1 regulates oligodendrocyte morphology. Presented at EuroGlia 2025 2025.
Festa LK, Sciutto AL, Grinspan JB, Jordan-Sciutto KL: Activation of the lysosomal cation channel TRPML1 controls oligodendrocyte actin polymerization and prevents bictegravir-mediated inhibition of oligodendrocyte maturation. Presented at the International Society of Neurovirology Conference 2025.
Festa LK, Grinspan JB, Jordan-Sciutto KL.: White matter injury across neurodegenerative disease. Trends Neurosci 47(1): 47-57, January 2024.
Festa LK, Grinspan JB, Jordan-Sciutto KL: TRPML1 is a novel regulator of the oligodendrocyte cytoskeleton. Presented at the 10th Tykeson Fellows Conference 2024 Notes: Poster.
Festa, L, Chen S, Grinspan JB, Jordan-Sciutto KL: TRPML1 modulates the oligodendrocyte cytoskeleton via Rac1. Presented at the American Society for Neurochemistry 2024 Notes: Poster.
Festa L, Grinspan JB, Jordan-Sciutto KL: TRPML1 is a novel regulator of the oligodendrocyte cytoskeleton Presented at the Myelin Gordon Research Seminar 2024 Notes: Poster.
Festa LK, Clyde AE, Long CC, Roth LM, Grinspan JB, Jordan-Sciutto KL.: Antiretroviral treatment reveals a novel role for lysosomes in oligodendrocyte maturation. J Neurochem 165(5): 722-740, June 2023.