Ryan M Carey, M.D.

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Assistant Professor of Otorhinolaryngology: Head and Neck Surgery at the Hospital of the University of Pennsylvania
Attending Surgeon, Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA
Attending Surgeon, University of Pennsylvania Health System, Philadelphia, PA
Department: Otorhinolaryngology: Head and Neck Surgery

Contact information
Department of Otolaryngology-Head & Neck Surgery
University of Pennsylvania
3400 Spruce Street, 5 Ravdin
Philadelphia, PA 19104
B.S.E. (Bioengineering)
University of Pennsylvania School of Engineering and Applied Sciences, Philadelphia, PA, 2013.
M.D. (Medicine)
Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, 2017.
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Description of Clinical Expertise

Dr. Carey provides advanced medical and surgical head and neck cancer care and reconstructive services to patients at the Hospital of the University of Pennsylvania and the Veteran’s Administration Medical Center. He specializes in head and neck oncologic surgery, transoral robotic surgery (TORS), and microvascular reconstructive surgery.

Description of Research Expertise

Dr. Carey is a surgeon-scientist engaged in research aimed at improving the diagnosis and treatment of head and neck cancer. He runs a cancer neuroscience lab that investigates how head and neck cancer cells interact with the local tumor environment. His lab is specifically focused on G-protein coupled receptors including taste receptors and how the involved signaling pathways can regulate important cellular processes in head and neck cancer. The goal is to leverage taste receptors as biomarkers or therapeutic targets for treating malignancies. His group is actively translating their basic science findings from bench to bedside through clinical trials on therapies developed in the lab.

Selected Publications

Patel AM, Haleem A, Choudhry HS, Brody RM, Brant JA, Carey RM: Elective neck dissection in cT1-4 N0M0 head and neck basaloid carcinoma. Otolaryngology-Head and Neck Surgery April 2024.

Patel AM, Haleem A, Choudhry HS, Brant JA, Brody RM, Carey RM: Surgical Resection Improves Overall Survival in cT4b Major Salivary Gland Cancer. Otolaryngology-Head and Neck Surgery March 2024.

Patel AM, Haleem A, Maxwell R, Lukens JN, Lin A, Brody RM, Brant JA, Carey RM: Choice of adjuvant radiotherapy facility in major salivary gland cancer. Laryngoscope February 2024.

Carey RM, Anagnos VJ, Prasad A, Sangal NR, Rajasekaran K, Shanti RM, Cannady SB, Newman JG, Brant JA, Brody RM: Nodal Metastasis in Surgically Treated Oral Cavity Squamous Cell Carcinoma. Journal for Oto-Rhino-Laryngology November 2023.

Miller ZA, Jolivert JF, Ma RZ, Muthuswami S, Mueller A, McMahon DB, Carey RM, Lee RJ: Lidocaine Induces Apoptosis in Head and Neck Squamous Cell Carcinoma Through Activation of Bitter Taste Receptor T2R14. Cell Reports November 2023.

Carey RM, Prasad A, Wei K, Brant JA, Brody RM, Leibowitz JM, Civantos FJ, Sweeny L: Primary Site Surgery in Distantly Metastatic Oropharyngeal Squamous Cell Carcinoma. The Laryngoscope November 2023.

Peifer S, Carey R, Nisenbaum E, Leibowitz J, Nicolli E.: Cautionary case for radial forearm free flap use in trisomy 21. Head Neck Oct 2023.

Shah K, Carey RM, Prasad A, Panara K, Rajasekaran K, Cannady SB, Brant JA, Brody RM: Postoperative Radiation Therapy Refusal in Major Salivary Gland Cancers. Otolaryngol Head Neck Surg 169((3)): 577-588, Sep 2023.

Prasad A, Carey RM, Panara K, Rajasekaran K, Cannady SB, Newman JG, Brant JA, Brody RM.: Nodal metastasis in surgically treated laryngeal squamous cell carcinoma. Head Neck Jul 2023.

Kohanski MA, Ungerer H, Xu K, Douglas JE, Carey RM, Rassekh CH, Chao TN, Weinstein ML, Atkins JH: Randomized controlled trial assessing intubation time with and without an aerosol biocontainment device. J Head Neck Anes 7(1): e43, Jun 2023.

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Last updated: 05/19/2024
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