Kyle Bittinger, Ph.D.

faculty photo
Assistant Professor of Pediatrics at the Children's Hospital of Philadelphia
Department: Pediatrics

Contact information
CHOP Microbiome Center
Roberts Center for Pediatric Research
2716 South Street, 14th Floor
Philadelphia, PA 19146-2305
Office: 267-425-1641
Education:
B.S. (Chemistry)
University of Pittsburgh, 2001.
Ph.D. (Physical Chemistry)
Massachusetts Institute of Technology, 2008.
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Selected Publications

Najem CE, Lee J, Tanes CE, Strange WC, Friedman E, Sreih AG, Rhee RL, Geara A, Li H, Bittinger K, Lewis JD, Wu GD, Merkel PA: Characterizing the gut and plasma metabolome in patients with ANCA-associated vasculitis. 2018 ACR/ARHP Annual Meeting, Chicago IL (accepted) Oct 22 2018 Notes: Poster presentation.

Graham K, Tanes C, Bittinger K, Lemke A, Heuckeroth R: Restoration of anti-inflammatory microbial community in children with Hirschsprung disease after pull-through surgery. NASPGHAN 2018, Hollywood, FL (accepted) Oct 24-27 2018 Notes: Poster presentation.

Friedman Elliot S, Li Yun, Shen Ting-Chin David, Jiang Jack, Chau Lillian, Adorini Luciano, Babakhani Farah, Edwards Jeffrey, Shapiro David, Zhao Chunyu, Carr Rotonya M, Bittinger Kyle, Li Hongzhe, Wu Gary D: FXR-Dependent Modulation of the Human Small Intestinal Microbiome by the Bile Acid Derivative Obeticholic Acid. Gastroenterology Aug 2018 Notes: doi: 10.1053/j.gastro.2018.08.022 [Epub ahead of print]

Liu L, Firrman J, Tanes C, Bittinger K, Thomas-Gahring A, Wu GD, Van den Abbeele P, Tomasula P: Establishing a mucosal gut microbial community in vitro using an artificial simulator. PLoS One 13(7: e0197692): 1-20, Jul 17 2018 Notes: https://doi.org/10.1371/journal.pone.0197692

Rhee Rennie L, Sreih Antoine G, Najem Catherine E, Grayson Peter C, Zhao Chunyu, Bittinger Kyle, Collman Ronald G, Merkel Peter A: Characterisation of the nasal microbiota in granulomatosis with polyangiitis. Annals of the rheumatic diseases Jul 2018.

Uribe-Herranz M, Bittinger K, Rafail S, Guedan S, Pierini S, Tanes C, Gill SA, Tany J, Morgan MA, Bushman FD, June CH, Facciabene A: Gut microbiota modulates adoptive cell therapy via CD8α dendritic cells. Cancer Research (Immunology); Proceedings: AACR Annual Meeting 2018, April 14-18, 2018, Chicago, IL 78(13 Supplement), Jul 2018 Notes: http://cancerres.aacrjournals.org/content/78/13_Supplement/3798.short Abstract Nr 3798; doi: 10.1158/1538-7445. AM2018-3798.

Facciabene A, Rafail S, Gil de Gomez L, Pierini S, Uribe-Herranz M, Bittinger K: Gut microbiota SCFA modulates DCs antigen presentation and impacts tumor response to radiotherapy. Cancer Research; Proceedings: AACR Annual Meeting 2018, April 14-18, 2018, Chicago, IL 78(13 Suppl): Abstract Nr 666, Jul 2018 Notes: http://cancerres.aacrjournals.org/content/78/13_Supplement/666.short; Abstract 666

Zhao C, Bittinger K, Liang G, Mattei L, Galgano AC, Hofstaedter CE, Montgomery S, Roundtree S, Baldassano R, Bushman FD: Pediatric clostridium difficile isolates from Philadelphia analyzed using multiple minion sequencing. ASM Microbe 2018, Atlanta, GA Jun 10 2018.

Clarke EL, Taylor LJ, Zhao C, Connell J, Bushman FD, Bittinger K: Sunbeam: an extensible pipeline for analyzing metagenomic sequencing experiments. bioRxiv Jun 2018 Notes: https://doi.org/10.1101/326363.

Friedman ES*, Shen TD*, Li Y*, Jiang J, Chau L, Adorini L, Babakhani F, Edwards J, Zhao C, Bittinger K, Li H, Wu, GD. *Contributed equally. : FXR-dependent modification of the human small intestinal microbiome. Digestive Disease Week 2018, Washington DC Jun 3 2018 Notes: Oral presentation.

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Last updated: 08/29/2018
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