Donald Joseph, Ph.D.

faculty photo
Research Assistant Professor of Neurology
Department: Neurology

Contact information
3400 Civic Center Boulevard
Philadelphia, PA 19104
Office: 2155945285
Lab: 2155945285
BS (Biology)
Medgar Evers College of the City University of New York, 1994.
MA (Neuroscience & Physiology)
City College of the City University of New York, 1998.
MA (Neuroscience)
Columbia University, 2001.
MPhil (Neuroscience)
Columbia University, 2003.
Ph.D (Neuroscience)
Columbia University, 2009.
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Description of Research Expertise

Electrophysiology of the synapse, Calcium-imaging, Long-Term Potentiation (LTP) recording, Cognitive Testing, electroencephalogram (EEG), and Genome-wide sequencing

Selected Publications

Siddiqi F, Trakimas AL, Joseph DJ, Lippincott ML, Marsh ED, Wolfe JH.: Islet1 Precursors Contribute to Mature Interneuron Subtypes in Mouse Neocortex. Cerebral Cortex 31(11): 5206-5224, Oct 2021.

Joseph DJ, Von Deimling M, Hasegawa Y, Cristancho AG, Risbud R, McCoy AJ, Marsh ED.: Protocol for isolating young adult parvalbumin interneurons from the mouse brain for extraction of high-quality RNA. STAR Protoc 2(3): 100714, Aug 2021.

F Siddiqi, AL Trakimas, DJ Joseph, TT Clarke, E. Marsh, J.H. Wolfe: Fate-labeling of Islet1 population shows pervasive progeny in mouse forebrain. Cerebral Cortex 2021 Notes: in-press.

Joseph DJ, Von Deimling M, Hasegawa Y, Cristancho AG, Ahrens-Nicklas RC, Rogers SL, Risbud R, McCoy AJ, Marsh ED.: Postnatal Arx transcriptional activity regulates functional properties of PV interneurons. iScience 24: 101999, Dec 2020.

Joseph DJ, Liu C, Peng J, Liang G, Wei H.: Isoflurane mediated neuropathological and cognitive impairments in the triple transgenic Alzheimer's mouse model are associated with hippocampal synaptic deficits in an age-dependent manner. PLoS One 14: e0223509, Oct 2019.

Peng J, Drobish JK, Liang G, Wu Z, Liu C, Joseph DJ, Abdou H, Eckenhoff MF, Wei H.: Anesthetic preconditioning inhibits isoflurane-mediated apoptosis in the developing rat brain. Anesth Analg 119(4): 939-946, Oct 2014.

Zhao X, Yang Z, Liang G, Wu Z, Peng Y, Joseph DJ, Inan S, Wei H.: Dual effects of isoflurane on proliferation, differentiation, and survival in human neuroprogenitor cells. Anesthesiology 118(3): 537-49, Mar 2013.

Peng J, Liang G, Inan S, Wu Z, Joseph DJ, Meng Q, Peng Y, Eckenhoff MF, Wei H.: Dantrolene ameliorates cognitive decline and neuropathology in Alzheimer triple transgenic mice. Neurosci Lett 516(2): 274-9, May 2012.

Joseph DJ, Williams DJ, MacDermott AB.: Modulation of neurite outgrowth by activation of calcium-permeable kainate receptors expressed by rat nociceptive-like dorsal root ganglion neurons. Dev Neurobiol 71(10): 818-35, Oct 2011.

Joseph DJ, Choudhury P, Macdermott AB.: An in vitro assay system for studying synapse formation between nociceptive dorsal root ganglion and dorsal horn neurons. J Neurosci Methods 189: 197-204, Jun 2010.

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Last updated: 01/28/2022
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