Donald Joseph, Ph.D.
Research Assistant Professor of Neurology
Department: Neurology
Contact information
3400 Civic Center Boulevard
ARC-502C
Philadelphia, PA 19104
ARC-502C
Philadelphia, PA 19104
Office: 646-245-3677
Fax: 916-853-1669
Lab: 215-594-5285
Fax: 916-853-1669
Lab: 215-594-5285
Email:
josephd1@chop.edu
josephd1@chop.edu
Publications
Links
Search PubMed for articles
Professional site for biographical and research information
Professional site for biographical and research information
Search PubMed for articles
Professional site for biographical and research information
Professional site for biographical and research information
Education:
BS (Biology)
Medgar Evers College of the City University of New York, 1994.
MA (Neuroscience & Physiology)
City College of the City University of New York, 1998.
MA (Neuroscience)
Columbia University, 2001.
MPhil (Neuroscience)
Columbia University, 2003.
Ph.D (Neuroscience)
Columbia University, 2009.
Permanent linkBS (Biology)
Medgar Evers College of the City University of New York, 1994.
MA (Neuroscience & Physiology)
City College of the City University of New York, 1998.
MA (Neuroscience)
Columbia University, 2001.
MPhil (Neuroscience)
Columbia University, 2003.
Ph.D (Neuroscience)
Columbia University, 2009.
Description of Research Expertise
Electrophysiology of the synapse, Calcium-imaging, Long-Term Potentiation (LTP) recording, Cognitive Testing, electroencephalogram (EEG), and Genome-wide sequencingSelected Publications
Donald J Joseph, Markus Von Deimling, Rashmi Risbud, Almedia J McCoy, Eric D Marsh: Loss of Postnatal Arx Transcriptional Activity in Parvalbumin Interneurons Reveals Non-cell Autonomous Disturbances in CA1 Pyramidal Cells. Neuroscience Elsevier, May 23(24): S0306-4522, May 23 2024.F Siddiqi, AL Trakimas, DJ Joseph, TT Clarke, E. Marsh, J.H. Wolfe: Fate-labeling of Islet1 population shows pervasive progeny in mouse forebrain. Cerebral Cortex 31(11): 5206–5224, November 2021 Notes: in-press.
Siddiqi F, Trakimas AL, Joseph DJ, Lippincott ML, Marsh ED, Wolfe JH.: Islet1 Precursors Contribute to Mature Interneuron Subtypes in Mouse Neocortex. Cerebral Cortex 31(11): 5206-5224, Oct 2021.
Joseph DJ, Von Deimling M, Hasegawa Y, Cristancho AG, Risbud R, McCoy AJ, Marsh ED.: Protocol for isolating young adult parvalbumin interneurons from the mouse brain for extraction of high-quality RNA. STAR Protoc 2(3): 100714, Aug 2021.
Joseph DJ, Von Deimling M, Hasegawa Y, Cristancho AG, Ahrens-Nicklas RC, Rogers SL, Risbud R, McCoy AJ, Marsh ED.: Postnatal Arx transcriptional activity regulates functional properties of PV interneurons. iScience 24: 101999, Dec 2020.
Joseph DJ, Liu C, Peng J, Liang G, Wei H.: Isoflurane mediated neuropathological and cognitive impairments in the triple transgenic Alzheimer's mouse model are associated with hippocampal synaptic deficits in an age-dependent manner. PLoS One 14: e0223509, Oct 2019.
Peng J, Drobish JK, Liang G, Wu Z, Liu C, Joseph DJ, Abdou H, Eckenhoff MF, Wei H.: Anesthetic preconditioning inhibits isoflurane-mediated apoptosis in the developing rat brain. Anesth Analg 119(4): 939-946, Oct 2014.
Zhao X, Yang Z, Liang G, Wu Z, Peng Y, Joseph DJ, Inan S, Wei H.: Dual effects of isoflurane on proliferation, differentiation, and survival in human neuroprogenitor cells. Anesthesiology 118(3): 537-49, Mar 2013.
Peng J, Liang G, Inan S, Wu Z, Joseph DJ, Meng Q, Peng Y, Eckenhoff MF, Wei H.: Dantrolene ameliorates cognitive decline and neuropathology in Alzheimer triple transgenic mice. Neurosci Lett 516(2): 274-9, May 2012.
Joseph DJ, Williams DJ, MacDermott AB.: Modulation of neurite outgrowth by activation of calcium-permeable kainate receptors expressed by rat nociceptive-like dorsal root ganglion neurons. Dev Neurobiol 71(10): 818-35, Oct 2011.