Wenli Yang, PhD

faculty photo
Research Assistant Professor of Medicine
Department: Medicine

Contact information
Institute for Regenerative Medicine
University of Pennsylvania
Smilow Center for Translational Research, 11th Floor, Rm 177
3400 Civic Center Boulevard
Philadelphia, PA 19104
Office: 215-746-0589
Fax: 215-573-2094
Education:
BS (Biochemistry)
University of Illinois, Urbana-Champaign, 1995.
PhD (Microbiology and Molecular Genetics)
University of California, Los Angeles, 2001.
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Selected Publications

Yang, W: A large diverse collection of hiPSCs and differentiated hepatocyte-like cells uncover functional genetic variation at blood lipid-associated loci. International Society for Stem Cell Research 15th Annual Meeting, pre-meeting focus session; Boston, MA Jun 2017 Notes: Oral presentation.

Liu Y, Conlon DM, Bi X, Slovik KJ, Shi J, Edelstein HI, Millar JS, Javaheri A, Cuchel M, Pashos EE, Iqbal J, Hussain MM, Hegele RA, Yang W, Duncan SA, Rader DJ, Morrisey EE: Lack of MTTP Activity in Pluripotent Stem Cell-Derived Hepatocytes and Cardiomyocytes Abolishes apoB Secretion and Increases Cell Stress. Cell Rep 19(7): 1456-1466, May 2017.

Cayo MA, Mallanna SK, Di Furio F, Jing R, Tolliver LB, Bures M, Urick A, Noto FK, Pashos EE, Greseth MD, Czarnecki M, Traktman P, Yang W, Morrisey EE, Grompe M, Rader DJ, Duncan SA: A Drug Screen using Human iPSC-Derived Hepatocyte-like Cells Reveals Cardiac Glycosides as a Potential Treatment for Hypercholesterolemia. Cell Stem Cell 20(4): 478-489.e5, Apr 2017.

Pashos EE*, Park Y*, Wang X*, Raghavan A*, Yang W*, Abbey D, Peters DT, Arbelaez J, Hernandez M, Kuperwasser N, Li W, Lian Z, Liu Y, Lv W, Lytle-Gabbin SL, Marchadier DH, Rogov P, Shi J, Slovik KJ, Stylianou IM, Wang L, Yan R, Zhang X, Kathiresan S, Duncan SA, Mikkelsen TS, Morrisey EE, Rader DJ, Brown CD, Musunuru K Pashos EP*, Wang X*, Raghavan A*, Yang W*, Park Y, Peters D, Arbelaez, J, Hernandez M,Kuperwasser N, Li W, Lian Z, Liu Y, Lv W, Marchadier DH, Rogov P, Shi J, Slovik KJ, StylianouIM, Wang L, Yan R, Zhang X, Kathiresan S, Duncan SA, Mikkelsen TS, Morrisey EE, Brown CD,Rader DJ*, Musunuru K*: Causal mechanisms for genetic variation in a population cohort of differentiated induced pluripotent stem cells. Cell Stem 20(4): 558-570, Mar 2017 Notes: *These authors contributed equally.

Yang W, Liu Y, Slovik KJ, Wu JC, Duncan SA, Rader DJ, Morrisey EE: Generation of iPSCs as a Pooled Culture Using Magnetic Activated Cell Sorting of Newly Reprogrammed Cells. PLoS One 10(8): e0134995, Aug 2015.

Zhang H, Xue C, Shah R, Bermingham K, Hinkle CC, Li W, Rodrigues A,Tabita-Martinez J, Millar JS, Cuchel M, Pashos EE, Liu Y, Yan R, Yang W, Gosai SJ, VanDorn D, Chou ST, Gregory BD, Morrisey EE, Li M, Rader DJ, Reilly MP.: Functional analysis and transcriptomic profiling of iPSC-derived macrophages and their application in modeling Mendelian disease. Circ Res 117(1): 17-28, Jun 2015.

Liu W, Stein P, Cheng X, Yang W, Shao NY, Morrisey EE, Schultz RM, You J: BRD4 regulates Nanog expression in mouse embryonic stem cells and preimplantation embryos. Cell Death Differ 21(12): 1950-1960, Dec 2014.

Yang, W: Generation of a lung stem cell ‘tool kit’ for derivation of functional lung epithelial lineages. 5th Annual NHLBI Progenitor Cell Biology Consortium meeting, Palo Alto, CA Sep 2014 Notes: Oral presentation.

Yang, W: To clone or not to clone: generation of iPS cells by batch selection of pooled culture. International Society for Stem Cell Research 12th Annual Meeting, pre-meeting focus session; Vancouver, Canada Jun 2014 Notes: Oral and poster presentation.

Yang, W: Induced Pluripotent Stem Cell Core Facility. NextGen Stem Cell Conference, Saratoga Springs,NY May 2014 Notes: Poster presentation.

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Last updated: 05/18/2018
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