Gary W. Falk, MD, MS

faculty photo
Professor of Medicine at the Hospital of the University of Pennsylvania
Clinical Co-Director, University of Pennsylvania, School of Medicine and the Children's Hospital of Philadelphia Joint Center for Digestive, Liver and Pancreatic Medicine
Co-Director, Joint Penn-CHOP Center for Digestive, Liver and Pancreatic Disorders
Member, Hospital of the University of Pennsylvania Abramson Comprehensive Cancer Center Cancer Control Research Program
University Associate Staff, Children's Hospital of Philadelphia
Director, Esophageal Program, Hospital of the University of Pennsylvania
Department: Medicine

Contact information
3400 Civic Center Boulevard
749 Perelman Center for Advanced Medicine
South Pavilion
Philadelphia, PA 19104
Office: 215-615-4951
Fax: 215-349-5915
Education:
HS
Stuyvesant High School, New York, New York , 1972.
B.S. (Biology-Geology. Cum laude with high distinction)
University of Rochester, Rochester, NY, 1976.
M.D.
University of Rochester School of Medicine and Dentistry, Rochester, NY, 1980.
M.S. (Clinical Research)
Case Western Reserve University School of Medicine Clinical Scholars Program, Cleveland, Ohio, 2006.
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Description of Clinical Expertise

Esophageal diseases including Barrett's esophagus, eosinophilic esophagitis, GERD diagnosis and treatment, achalasia, motility abnormalities, extraesophageal GERD, dysphagia, esophageal cancer

Description of Other Expertise

Consultative gastroenterology
Upper endosccopy
Endoscopic dilation
Endoscopic mucosal resection
Radiofrequency ablation
Pneumatic dilation
Colonoscopy
Polypectomy
High resolution manometry
BRAVO pH
Impedance pH
Hydrogen breath tests
Urea breath tests

Description of Research Expertise

Barrett's esophagus: chemoprevention, detection, diagnosis, cancer prevention, epidemiology, risk stratification, pathogenesis

Eosinophilic esophagitis: epidemiology, pediatric-adult transition, fibrosis, clinical trials, pathogenesis

Endoscopy: advanced imaging

Selected Publications

Robinson J, Furuta GT, Hadker N, Kolev I, Williams J, Juethner S, Falk GW.: Transition of Care from Pediatric to Adult Care in Eosinophilic Esophagitis: Insights From a Patient Perspective Survey. J Pediatr Gastroenterol Nutr 73: 722-726, Dec 2021.

Karakasheva TA, Gabre JT, Sachdeva UM, Cruz-Acuña R, Lin EW, DeMarshall M, Falk GW, Ginsberg GG, Yang Z, Kim MM, Diffenderfer ES, Pitarresi JR, Li J, Muir AB, Hamilton KE, Nakagawa H, Bass AJ, Rustgi AK.: Patient-derived organoids as a platform for modeling a patient's response to chemoradiotherapy in esophageal cancer. Sci Rep 11: 21304, Oct 2021.

Wani S, Yadlapati R, Singh S, Sawas T, Katzka DA; Post-Endoscopy Esophageal Neoplasia Expert Consensus Panel.: POST-ENDOSCOPY ESOPHAGEAL NEOPLASIA IN BARRETT'S ESOPHAGUS: CONSENSUS STATEMENTS FROM AN INTERNATIONAL EXPERT PANEL. Gastroenterology Oct 2021.

Shoda T, Wen T, Caldwell JM, Ben-Baruch Morgenstern N, Osswald GA, Rochman M, Mack LE, Felton JM, Abonia JP, Arva NC, Atkins D, Bonis PA, Capocelli KE, Collins MH, Dellon ES, Falk GW, Gonsalves N, Gupta SK, Hirano I, Leung J, Menard-Katcher PA, Mukkada VA, Putnam PE, Rudman Spergel AK, Spergel JM, Wechsler JB, Yang GY, Aceves SS, Furuta GT, Rothenberg ME; Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR) Investigators Group.: Loss of Endothelial TSPAN12 Promotes Fibrostenotic Eosinophilic Esophagitis via Endothelial Cell-Fibroblast Crosstalk. Gastroenterology Oct 2021.

Codipilly DC, Krishna Chandar A, Wang KK, Katzka DA, Goldblum JR, Thota PN, Falk GW, Chak A, Iyer PG.: Wide-area transepithelial sampling for dysplasia detection in Barrett's esophagus: a systematic review and meta-analysis. Gastrointest Endosc Sep 2021.

COREOS Collaborators:, Ma C, Schoepfer AM, Dellon ES, Bredenoord AJ, Chehade M, Collins MH, Feagan BG, Furuta GT, Gupta SK, Hirano I, Jairath V, Katzka DA, Pai RK, Rothenberg ME, Straumann A, Aceves SS, Alexander JA, Arva NC, Atkins D, Biedermann L, Blanchard C, Cianferoni A, Ciriza de Los Rios C, Clayton F, Davis CM, de Bortoli N, Dias JA, Falk GW, Genta RM, Ghaffari G, Gonsalves N, Greuter T, Hopp R, Hsu Blatman KS, Jensen ET, Johnston D, Kagalwalla AF, Larsson HM, Leung J, Louis H, Masterson JC, Menard-Katcher C, Menard-Katcher PA, Moawad FJ, Muir AB, Mukkada VA, Penagini R, Pesek RD, Peterson K, Putnam PE, Ravelli A, Savarino EV, Schlag C, Schreiner P, Simon D, Smyrk TC, Spergel JM, Taft TH, Terreehorst I, Vanuytsel T, Venter C, Vieira MC, Vieth M, Vlieg-Boerstra B, von Arnim U, Walker MM, Wechsler JB, Woodland P, Woosley JT, Yang GY, Zevit N, Safroneeva E.: Development of a core outcome set for therapeutic studies in eosinophilic esophagitis (COREOS). J Allergy Clin Immunol Jul 2021.

Dellon ES, Collins MH, Katzka DA, Mukkada VA, Falk GW, Morey R, Goodwin B, Eisner JD, Lan L, Desai NK, Williams J, Hirano I; ORBIT2/SHP621-302 Investigators.: Long-Term Treatment of Eosinophilic Esophagitis With Budesonide Oral Suspension. Clin Gastroenterol Hepatol Jun 2021.

Vajravelu RK, Kolb JM, Thanawala SU, Scott FI, Han S, Singal AG, Falk GW, Katzka DA, Wani S.: Characterization of Prevalent, Post-Endoscopy, and Incident Esophageal Cancer in the United States: A Large Retrospective Cohort Study. Clin Gastroenterol Hepatol lin Gastroenterol Hepatol, 2021.

Kolb JM, Han S, Scott FI, Murphy CC, Hosokawa P, Wani S; Early Onset Esophageal Adenocarcinoma Study Group.: Early-Onset Esophageal Adenocarcinoma Presents With Advanced-Stage Disease But Has Improved Survival Compared With Older Individuals. Gastroenterology 159: 2238-2240, Dec 2020.

Wani S, Williams JL, Falk GW, Komanduri S, Muthusamy VR, Shaheen NJ.: An Analysis of the GIQuIC Nationwide Quality Registry Reveals Unnecessary Surveillance Endoscopies in Patients With Normal and Irregular Z-Lines. Am J Gastroenterol 115: 1869-1878, Nov 2020.

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Last updated: 11/23/2021
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