Edna Mancilla, MD
Professor of Clinical Pediatrics (Endocrinology and Diabetes)
Attending Physician, Division of Endocrinology, Children's Hospital of Philadelphia
Consulting Endocrinologist, Pennsylvania Hospital
Department: Pediatrics
Contact information
Children's Hospital of Philadelphia
Division of Endocrinology and Diabetes
3500 Civic Center Blvd
Philadelphia, PA 19104
Division of Endocrinology and Diabetes
3500 Civic Center Blvd
Philadelphia, PA 19104
Office: 215 590 3174
Fax: 215 590 3053
Fax: 215 590 3053
Email:
mancillae@email.chop.edu
mancillae@email.chop.edu
Education:
MD (Medicine)
University of Chile, 1987.
Permanent linkMD (Medicine)
University of Chile, 1987.
Description of Clinical Expertise
Disorders of bone and calcium metabolism in childrenDescription of Research Expertise
Bone and calcium metabolism, clinical researchFibrodysplasia Ossificans Progressiva, clinical care and research
Growth plate
Selected Publications
Craven M, Vajravelu ME, Shekdar KV, Levine MA, Mumm S, Whyte MP, Mancilla EE: Early identification of a 12-bp tandem duplication in TNFRSF11A encoding receptor activator of nuclear factor-kappa B (RANK): clinical characterization and response to bisphosphonate therapy. Bone. 2023 Feb 3:116698. doi: 10.1016/j.bone.2023.116698. Online ahead of print Feb 2023.Angela M Cheung,Edward C Hsiao,Robert J Pignolo,Mona Al Mukaddam,Geneviève Baujat,Staffan K Berglund,Carmen De Cunto,Patricia Delai,Peter Kannu,Richard Keen, Edna E Mancilla, Rose Marino,Andrew Strahs, Frederick S Kapla: Long-Term Impact of Palovarotene Treatment on Heterotopic Ossification in Patients with Fibrodysplasia Ossificans Progressiva: Data from the Phase III MOVE Trial. ASBMR 2023 Annual Meeting 2023.
Geneviève Baujat,Edward C Hsiao,Robert J Pignolo,Mona Al Mukaddam,Staffan K Berglund,Angela M Cheung,Carmen De Cunto,Patricia Delai,Peter Kannu,Richard Keen, Edna E Mancilla, Rose Marino, Andrew Strahs, Frederick S Kaplan: Efficacy of Palovarotene for the Reduction of New Heterotopic Ossification in Patients with Fibrodysplasia Ossificans Progressiva: Sensitivity Analyses from the Phase III MOVE Trial. ASBMR2023 Annual Meeting 2023.
Pignolo RJ, Hsiao EC, Al Mukaddam M, Baujat G, Berglund SK, Brown MA, Cheung AM, De Cunto C, Delai P, Haga N, Kannu P, Keen R, Sang KQ, Mancilla EE, Marino R, Strahs A, Kaplan FS : Reduction of New Heterotopic Ossification (HO) in the Open-Label, Phase 3 MOVE Trial of Palovarotene for Fibrodysplasia Ossificans Progressiva (FOP). Journal of Bone and Mineral Research Page: doi: 10.1002, Dec 2022 Notes: epub ahead of print.
Rychik J, Goldberg DJ, Rand E, Mancilla EE, Heimall J, Seivert N, Campbell D, O'Malley S, Dodds KM.: A Path FORWARD: Development of a Comprehensive Multidisciplinary Clinic to Create Health and Wellness for the Child and Adolescent with a Fontan Circulation. Pediatr Cardiol 43(6): 1175-1192, May 2022.
Brittney Newby, Edna E Mancilla: Disorders of calcium and bone metabolism. Netter's Pediatrics. Rebecca Tenney Soeiro Erin Pete Devon (eds.). Elsevier, Page: 55-60, March 2022.
Robert J. Pignolo,Mona Al Mukaddam,Geneviève Baujat,Matthew A. Brown,Angela M. Cheung,Carmen L. De Cunto,Patricia Delai,Edward C. Hsiao,Peter Kannu, Richard Keen, Edna E. Mancilla, Staffan K. Berglund, Rose Marino, Andrew Strahs, Frederick S. Kaplan: Palovarotene for the Treatment of Fibrodysplasia Ossificans Progressiva in Females Aged ≥8 Years and Males Aged ≥10 Years: Data from the Phase III MOVE Trial. American Society of Bone and Mineral Research meeting, Virtual, poster October 2021.
Mona Al Mukaddam,Robert J. Pignolo,Geneviève Baujat,Matthew. A. Brown, Angela M. Cheung,Carmen L. De Cunto,Patricia Delai, Edward C. Hsiao, Peter Kannu, Richard Keen, Edna E. Mancilla, Staffan K. Berglund, Rose Marino, Andrew Strahs, Frederick S. Kaplan: Efficacy of Palovarotene in Patients Who Transferred From a Fibrodysplasia Ossificans Progressiva Natural History Study to the Phase III MOVE Trial. American Society of Bone and Mineral Research meeting, Virtual, poster October 2021.
Mancilla EE, Zielonka B, Roizen JD, Dodds KM, Rand EB, Heimall JR, Chen F, Wu C, Goldberg DJ, Rychik J.: Growth in Children with a Fontan Circulation. J Pediatr 235(1): 149-155, Aug 2021.
Kaplan FS, Teachey DT, Andolina JR, Siegel DM, Mancilla EE, Hsiao EC, Al Mukaddam M, Rocke DM, Pignolo RJ.: Off-on-off-on use of imatinib in three children with fibrodysplasia ossificans progressiva. Bone 150(4): 116016, May 2021.