Mona Al Mukaddam, M.D., M.S.
Professor of Clinical Medicine (Endocrinology, Diabetes and Metabolism)
Department: Medicine
Contact information
3rd floor Penn Medicine University City
3737 Market Street
Philadelphia, PA 19104
3737 Market Street
Philadelphia, PA 19104
Office: 215-662-9905
Links
Penn Bone Center
Interviewed by checkrare after Palovarotene was approved by the FDA and the first and only treatment for FOP.
Podcast on Women's Health in FOP
Webinar for BMT organization on "Bone Health after Transplant"
Patient educational Video for Penn Medicine: Journey of osteoporotic patients through falls and fractures
Patient Educational Videos at Penn Medicine: Osteoporosis Medications differences between anti resorptive and osteo anabolic therapies
Remembering Carol Orzel, FOP patient, who donated her skeleton to the the mutter museum.
CME titled "First Do No Harm: Realizing Timely Diagnosis and Treatment for Patients with Fibrodysplasia Ossificans Progressiva"
What Clinicians Need to Know About Fibrodysplasia Ossificans Progressiva, Interview with CheckRare
Patient Educational Video at Penn Medicine: Osteoporosis Myths and Facts
Penn Primary Care Podcast discussing osteoporosis Hosted by Drs Amber Bird, Deepa Rani Nandiwada and Mona Al Mukaddam
CureTalk@penn: How Is Fibrodysplasia Ossificans Progressiva (FOP) First Detected?
Webinar on COVID-19 vaccinations in FOP patients
Endocrinology Spotlight Series: Management of Calcium and Metabolic Bone Disorders Expert Guidance for Challenging Cases
Commentary regarding type 1 diabetes and bone in medpage today
Report on a patient with a rare bone disease correctly diagnosed at the Penn Bone Center
CDC sponsored virtual grand round on evaluation and management of bone health in patients with Thalassemia https://www.cdc.gov/ncbddd/thalassemia/webinar-archives.html
International Fibrodysplasia Ossificans Progressiva Association
Penn bone Center featured in Penn Medicine Women's health newsletter
Global CME on treatment considerations in Fibrodysplasia Ossificans Progressiva (FOP)
Interviewed for a Penn primary care podcast to discuss osteoporosis
Official website for International Clinical Council on Fibrodysplasia Ossificans Progressiva
Penn Bone Center
Interviewed by checkrare after Palovarotene was approved by the FDA and the first and only treatment for FOP.
Podcast on Women's Health in FOP
Webinar for BMT organization on "Bone Health after Transplant"
Patient educational Video for Penn Medicine: Journey of osteoporotic patients through falls and fractures
Patient Educational Videos at Penn Medicine: Osteoporosis Medications differences between anti resorptive and osteo anabolic therapies
Remembering Carol Orzel, FOP patient, who donated her skeleton to the the mutter museum.
CME titled "First Do No Harm: Realizing Timely Diagnosis and Treatment for Patients with Fibrodysplasia Ossificans Progressiva"
What Clinicians Need to Know About Fibrodysplasia Ossificans Progressiva, Interview with CheckRare
Patient Educational Video at Penn Medicine: Osteoporosis Myths and Facts
Penn Primary Care Podcast discussing osteoporosis Hosted by Drs Amber Bird, Deepa Rani Nandiwada and Mona Al Mukaddam
CureTalk@penn: How Is Fibrodysplasia Ossificans Progressiva (FOP) First Detected?
Webinar on COVID-19 vaccinations in FOP patients
Endocrinology Spotlight Series: Management of Calcium and Metabolic Bone Disorders Expert Guidance for Challenging Cases
Commentary regarding type 1 diabetes and bone in medpage today
Report on a patient with a rare bone disease correctly diagnosed at the Penn Bone Center
CDC sponsored virtual grand round on evaluation and management of bone health in patients with Thalassemia https://www.cdc.gov/ncbddd/thalassemia/webinar-archives.html
International Fibrodysplasia Ossificans Progressiva Association
Penn bone Center featured in Penn Medicine Women's health newsletter
Global CME on treatment considerations in Fibrodysplasia Ossificans Progressiva (FOP)
Interviewed for a Penn primary care podcast to discuss osteoporosis
Official website for International Clinical Council on Fibrodysplasia Ossificans Progressiva
Education:
BS
American University of Beirut, Lebanon, 2001.
MD
American University of Beirut, Lebanon, 2005.
MS
University of Pennsylvania, Institute of Translational Medicine and Therapeutics, 2013.
Permanent linkBS
American University of Beirut, Lebanon, 2001.
MD
American University of Beirut, Lebanon, 2005.
MS
University of Pennsylvania, Institute of Translational Medicine and Therapeutics, 2013.
Description of Clinical Expertise
Rare bone disease with expertise in Fibrodysplasia Ossificans Progressiva and hypophosphatasia. Metabolic bone and calcium disorders including osteoporosis, Paget's disease, hypo- and hyper-parathyroidism as well as bone diseases related to transplant, medications (example aromatase inhibitors and glucocorticoids) and iron overload.Description of Research Expertise
Clinical research in Fibrodysplasia Ossificans Progressiva and hypophosphatasia.Evaluation of osteoporosis and the effects of treatment/diseases on "bone quality" using high resolution imaging of bone (uMRI).
Selected Publications
Cassandra Crompton, Kassidy Baum, Michael Silvey, Mona Al Mukaddam: Comparison of Forteo® and PF708 teriparatide on improvements in bone mineral density JAPhA Pharmacotherapy Jan 2026.Scott C, Al Mukaddam M, Davis M, De Cunto CL, Hsiao EC, Pignolo RJ, Schwegler O, Artyomenko A, Croskery K, Hanman K, Sanchot B, Warnants E, Kaplan FS : Identifying global trends from case reports of fibrodysplasia ossificans progressiva: a scoping review. Ther Adv Musculoskelet Dis. Dec 2025.
Rahaf Sultan and Mona Al Mukaddam : "Bone Health and Prevalence of Low Bone Density/Osteoporosis in Gender Diverse Adults; A retrospective Study" ASBMR annual meeting Sept 2025.
Frederick S Kaplan, Mona Al Mukaddam, Genevieve Baujat, Alberto Hidalgo Bravo, Matthew Brown, Amanda Cali, Tae-Joon Cho, Corrie Crowe, Carmen L De Cunto, Patricia L R Delai, Robert J Diecidue, Elisabeth Marelise W Eekhoff, Lisa Friedlander, Clive S Friedman, Zvi Grunwald, Nobuhiko Haga, Edward C Hsiao, Richard Keen, Joseph A Kitterman, Charles Levy, Vrisha Madhuri, Rolf Morhart, J Coen Netelenbos, Christiaan Scott, Eileen M Shore, Michael Zasloff, Keqin Zhang, Robert J Pignolo: Medical Guidelines for Fibrodysplasia Ossificans Progressiva. JBMR Plus Sept 2025.
Marah Alsayed Hasan, Mona Al Mukaddam : Burosumab Use in FGF-23 Mediated Hypophosphatemia in McCune Albright Syndrome. Poster Presentation at the Annual ASBMR meeting Sept 2025.
Cassandra Crompton, PharmD; Kassidy Baum, PharmD; Michael Silvey, PharmD; Mona Al Mukaddam, MD, MS: Comparison of Forteo® and Teriparatide on Improvements in Bone Mineral Density Poster Presentation at Endocrine Society Annual Meeting July 2025.
Javier Ocampo Mascaro, Katherine Toder, Staci Kallish, Mona Al Mukaddam : Applying the Hypophosphatasia Diagnostic Criteria in a Patient Cohort at the Penn Bone Center Post Presentation at Endocrine Society Annual Meeting July 2025.
Bassam AlHamer and Mona Al Mukaddam : Silicosis Induced Hypercalcemia Treated with Ketoconazole Post Presentation at Endocrine Society Annual Meeting July 2025.
Natalie Dapas, Mona Al Mukaddam, Hamdee Attallah, Carrie M. Burns, Robert Jones, Julia Kharlip, Kristen Noelle Kobaly, Serena Cardillo: Creation of Educational Resources to Improve Endocrine Fellow Outpatient Curriculum. Poster Presentation at Endocrine Society Annual Meeting July 2025.
Pignolo RJ, Al Mukaddam M, Broski S, Morhart R, Drake LT, Kneeland B, Towler OW, Kaplan FS. : Ectopic pseudojoints in fibrodysplasia ossificans progressiva. JBMR Plus June 2025.