Taisei J. Kobayashi, MD

Assistant Professor of Clinical Medicine (Cardiovascular Medicine)
Co-Director of the Coronary Chronic Total Occlusion Team, Hospital of the University of Pennsylvania
Leadership committee of the Pulmonary Embolism Response Team, Hospital of the University of Pennsylvania
Co-Director of the Penn Denervation Center, Hospital of the University of Pennsylvania
Director of Interventional Cardiovascular Services, Michael J Crescenz Veterans Affairs Hospital
Department: Medicine
Contact information
Perelman Center for Advanced Medicine
11th Floor South Pavilion
3400 Civic Center Boulevard
Philadelphia, PA 19104
11th Floor South Pavilion
3400 Civic Center Boulevard
Philadelphia, PA 19104
Office: 215-614-6093
Fax: 215-349-5894
Fax: 215-349-5894
Education:
BA
Johns Hopkins University, 2006.
MD (Medicine)
Case Western Reserve University, 2010.
Permanent linkBA
Johns Hopkins University, 2006.
MD (Medicine)
Case Western Reserve University, 2010.
Description of Clinical Expertise
Renal DenervationComplex Coronary Interventions
Chronic Total Occlusions
Endovascular Arterial and Venous interventions
Pulmonary Arterial Sensor implantation
Advanced management and escalation of interventional therapies for Deep Venous thrombosis and pulmonary embolism
Structural heart disease including TAVR
Cardiogenic shock interventions including percutaneous mechanical support
Description of Research Expertise
Radiofrequency Renal DenervationUltrasound Renal Denervation
COVID - 19 related cardiovascular disease
Cardiovascular Outcomes research
Pulmonary Embolism
TAVR outcomes research
Selected Publications
Tung M, Kobayashi T, Swaminathan RV, Cohen DL, Feldman DN, Fulton B.: Renal Denervation: A Review of Current Devices, Techniques, and Evidence. Interv Cardiol Clin. April 2025.Nathan AS, Kennedy KF, Reddy KP, Fanaroff AC, Kolansky DM, Kobayashi TJ, Khatana SAM, Dayoub EJ, Eberly L, Rao SV, Mehran R, Bhatt D, Yeh RW, Spertus JA, Giri J.: Variation in Likelihood of Undergoing Percutaneous Coronary Intervention for ST-Segment-Elevation Myocardial Infarction Among US Hospitals. J Am Heart Assoc March 2025.
Pliakos E, Glassmoyer L, Kobayashi T, Pugliese S, Shankar H, Matthai W, Khandhar S, Giri J, Nathan A.: Economic Analysis of Catheter-Directed Thrombolysis for Intermediate-Risk Pulmonary Embolism. Catheter Cardiovasc Interv February 2025.
Faggioni M, Giri J, Glassmoyer L, Kobayashi T.: A Rational Approach to the Treatment of Acute Pulmonary Embolism. Annu Rev Med January 2025.
Ramadan OI, Yang L, Shultz K, Genovese E, Damrauer SM, Wang GJ, Secemsky EA, Treat-Jacobson DJ, Womeodu RJ, Fakorede FA, Nathan AS, Eberly LA, Julien HM, Kobayashi TJ, Groeneveld PW, Giri J, Fanaroff AC.: Racial, Socioeconomic, and Geographic Disparities in Preamputation Vascular Care for Patients With Chronic Limb-Threatening Ischemia. Circ Cardiovasc Qual Outcomes January 2025.
Bloch MJ, Kirtane AJ, Azizi M, Mahfoud F, Basile J, Daemen J, Saxena M, Thackeray L, McGuire M, Claude L, Schmeider RE, RADIANCE-HTN Investiators: 36-month durability of ultrasound renal denervation for hypertension resistant to combination therapy in RADIANCE-HTN TRIO. Hypertens Res 47(12): 3467-3472, Dec 2024.
Connolly JE, Herrmann HC, Atluri P, Desai N, Fiorilli PN, Giri J, Li RH, Kobayashi T, Nathan AS, Szeto WY, Grimm JC.: Transcatheter aortic valve replacement achieves similar predicted effective orifice area to surgical aortic valve replacement in bicuspid aortic stenosis. Cardiovasc Revasc Med. September 2024.
Brian Fulton 1, Jay Giri 1 2, Florian Rader 3, Debbie L Cohen 4, Taisei Kobayashi 1 2: Renal Denervation for Hypertension: The Current Landscape and Future Directions. Heart Int 66: 21-26, Sep 2024.
Pitoulis F, Tauber K, Atluri P, Szeto W, Anwarruddin S, Kobayashi T, Desai N, Cevasco M, Bermudez C, Acker M, Williams M, Ibrahim M.: The Challenges of Aortic Valve Management After Left Ventricular Assist Device Implantation. Ann Thorac Surg Short Rep. May 2024.
Kobayashi T, Secemsky EA, Klein AJ, Faintuch S, Bulman JC, Weinstein JL, Bitton-Faiwiszewski Y, Bisharat M, Metzger DC, Rosenberg RD, Weinberg I, Vadlamudi V, Matthai WH Jr, Saleh A, Cristea E, Lansky AJ, Giri J.: A Safety and Feasibility Single-Arm Study of a Novel Catheter Thrombectomy Device for the Treatment of Pulmonary Embolism (ENGULF). JSCAI-Journal of the Society for Cardiovascular Angiography & Interventions 3(6): 102049, May 2024.