Taisei J. Kobayashi | Faculty | About Us | Perelman School of Medicine | Perelman School of Medicine at the University of Pennsylvania

About Us
Our Faculty
Taisei J. Kobayashi

Taisei J. Kobayashi, MD

Assistant Professor of Clinical Medicine (Cardiovascular Medicine)

Co-Director of the Coronary Chronic Total Occlusion Team, Hospital of the University of Pennsylvania

Leadership committee of the Pulmonary Embolism Response Team, Hospital of the University of Pennsylvania

Co-Director of the Penn Denervation Center, Hospital of the University of Pennsylvania

Director of Interventional Cardiovascular Services, Michael J Crescenz Veterans Affairs Hospital

Department: Medicine

Contact information

Perelman Center for Advanced Medicine
11th Floor South Pavilion
3400 Civic Center Boulevard
Philadelphia, PA 19104

Office: 215-614-6093
Fax: 215-349-5894

Education:
BA
Johns Hopkins University, 2006.
MD (Medicine)
Case Western Reserve University, 2010.

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Description of Clinical Expertise

Renal Denervation
Complex Coronary Interventions
Chronic Total Occlusions
Endovascular Arterial and Venous interventions
Pulmonary Arterial Sensor implantation
Advanced management and escalation of interventional therapies for Deep Venous thrombosis and pulmonary embolism
Structural heart disease including TAVR
Cardiogenic shock interventions including percutaneous mechanical support

Description of Research Expertise

Radiofrequency Renal Denervation
Ultrasound Renal Denervation
COVID - 19 related cardiovascular disease
Cardiovascular Outcomes research
Pulmonary Embolism
TAVR outcomes research

Selected Publications

Bloch MJ, Kirtane AJ, Azizi M, Mahfoud F, Basile J, Daemen J, Saxena M, Thackeray L, McGuire M, Claude L, Schmeider RE, RADIANCE-HTN Investiators: 36-month durability of ultrasound renal denervation for hypertension resistant to combination therapy in RADIANCE-HTN TRIO. Hypertens Res 47(12): 3467-3472, Dec 2024.

Brian Fulton 1, Jay Giri 1 2, Florian Rader 3, Debbie L Cohen 4, Taisei Kobayashi 1 2: Renal Denervation for Hypertension: The Current Landscape and Future Directions. Heart Int 66: 21-26, Sep 2024.

Kobayashi T, Secemsky EA, Klein AJ, Faintuch S, Bulman JC, Weinstein JL, Bitton-Faiwiszewski Y, Bisharat M, Metzger DC, Rosenberg RD, Weinberg I, Vadlamudi V, Matthai WH Jr, Saleh A, Cristea E, Lansky AJ, Giri J.: A Safety and Feasibility Single-Arm Study of a Novel Catheter Thrombectomy Device for the Treatment of Pulmonary Embolism (ENGULF). JSCAI-Journal of the Society for Cardiovascular Angiography & Interventions 3(6): 102049, May 2024.

Azizi M, Sharp ASP, Fisher NDL, Weber MA, Lobo MD, Daemen J, Lurz P, Mahfoud F, Schmeider RE, Basile J, Bloch MJ, Saxena M, Wang Y, Sanghvi K, Jenkins JS, Devireddy C, Rader F, Gosse P, Claude L, Augustin DA, McClure CK, Kirtane AJ, RADIANCE Inestigators: Patient-Level Pooled Analysis of Endovascular Ultrasound Renal Denervation or a Sham Procedure 6 Months After Medication Escalation: The RADIANCE Clinical Trial Program. Circulation AHA 149(10): 747-759, Mar 2024.

John E Connolly 1, Howard C Herrmann 2, Pavan Atluri 3, Nimesh Desai 3, Paul N Fiorilli 2, Jay Giri 2, Robert H Li 4, Taisei Kobayashi 2, Ashwin S Nathan 2, Wilson Y Szeto 5, Joshua C Grimm 6: Transcatheter aortic valve replacement achieves similar predicted effective orifice area to surgical aortic valve replacement in bicuspid aortic stenosis. National Library of Medicine S1553-8389(24), Mar 2024.

Kobayashi T, Pugliese S, Sethi S, Parikh S, Goldberg J, Aljhafan F, Vitarello C, Rosenfield K, Lookstein R, Keeling B, Klein A, Gibson M, Glassmoyer L, Khandhar S, Secemsky E, Giri J.: Contemporary Management and Outcomes of Patients With High-Risk Pulmonary Embolism. Journal of the American College of Cardiology. Journal of the American College of Cardiology, 83(1): 35-43, Jan 2024.

Tran A, Toma C, Jaber W, Heintz J, Matthai WH, Palevsky H, Giri J, Kobayashi TJ, Nathan AS, Baumgartner S, Bashline M, Inci EK, Khandhar SJ.: Cost-Comparison of Mechanical Thrombectomy and Catheter-Directed Thrombolysis in Intermediate-Risk Pulmonary Embolism. JSCAI-Journal of the Society for Cardiovascular Angiography & Intervention 3(2): 101187, Oct 2023.

Julien H, Wang Y, Curtis J, Johnston-Cox H, Eberly L, Wang G, Nathan A, Fanaroff A, Khatana S, Groeneveld P, Secemsky E, Eneanya N, Vora A, Kobayashi T, Barbery C, Chery Godery, Kohi M, Kirksey L, Armstrong E, Jaff M, Giri J.: Racial Differences in Presentation and Outcomes After Peripheral Arterial Interventions: Insights From the NCDR-PVI Registry. Circulation: Cardiovascular Interventions. AHA Journal, 16(6): e011485, June 2023.

Kirtane AJ, Sharp ASP, Mahfoud F, Fisher NDL, Schmieder RE, Daemen J, Lobo MD, Lurz P, Basile J, Bloch MJ, Weber MA, Saxena M, Wang Y, Sanghvi K, Jenkins JS, Devireddy C, Rader F, Gosse P, Sapoval M, Barman NC, Claude L, Augustin D, Thackeray L, Mullin CM, Azizi M, RADIANCE Investigators and Collaberators : Patient-Level Pooled Analysis of Ultrasound Renal Denervation in the Sham-Controlled RADIANCE II, RADIANCE-HTN SOLO, and RADIANCE-HTN TRIO Trials. JAMA Cardiol 8(5): 464-473, May 2023.

Reddy KP, Eberly LA, Halaby R, Julien H, Khatana SAM, Dayoub EJ, Coylewright M, Alkhouli M, Fiorilli PN, Kobayashi TJ, Goldberg DM, Herrmann HC, Giri J, Groeneveld PW, Fanaroff AC, Nathan AS.: Racial, Ethnic and Socioeconomic Inequities in Access to Left Atrial Appendage Occlusion. J Am Heart Association 12(5): e028032, Feb 2023.