Taisei J. Kobayashi, MD
Associate Professor of Clinical Medicine (Cardiovascular Medicine)
Co-Director of the Coronary Chronic Total Occlusion Team, Hospital of the University of Pennsylvania
Co-Director of the Penn Denervation Center, Hospital of the University of Pennsylvania
Director of Interventional Cardiovascular Services, Michael J Crescenz Veterans Affairs Hospital
Department: Medicine
Contact information
Perelman Center for Advanced Medicine
11th Floor South Pavilion
3400 Civic Center Boulevard
Philadelphia, PA 19104
11th Floor South Pavilion
3400 Civic Center Boulevard
Philadelphia, PA 19104
Office: 215-614-6093
Fax: 215-349-5894
Fax: 215-349-5894
Education
BA
Johns Hopkins University, 2006.
MD (Medicine)
Case Western Reserve University, 2010.
Permanent linkBA
Johns Hopkins University, 2006.
MD (Medicine)
Case Western Reserve University, 2010.
Description of Clinical Expertise
Renal DenervationComplex Coronary Interventions
Chronic Total Occlusions
Endovascular Arterial and Venous interventions
Pulmonary Arterial Sensor implantation
Advanced management and escalation of interventional therapies for Deep Venous thrombosis and pulmonary embolism
Structural heart disease including TAVR
Cardiogenic shock interventions including percutaneous mechanical support
Description of Research Expertise
Radiofrequency Renal DenervationUltrasound Renal Denervation
COVID - 19 related cardiovascular disease
Cardiovascular Outcomes research
Pulmonary Embolism
TAVR outcomes research
Selected Publications
Denise M Hynes, Diana J Govier, Alex Hickok, Meike Niederhausen, Mazhgan Rowneki, Howard S Gordon, Taisei Kobayashi: Comparison of 30-Day Mortality After Diagnostic Coronary Angiography at VA and Community Hospitals. J Gen Intern Med January 2026.William Whang, Devi Nair, Rahul Bhardwaj, Marc Lahiri, Dinesh Sharma, Taisei Kobayashi, Shephal K Doshi, Andrea Natale, Craig Moskowitz, Moussa Mansour, Vijay Swarup, Mohit K Turagam, Srinivas Dukkipati, Matthew C Hyman, Sanghamitra Mohanty, Jeff Lam, Ugur Gurol, Carla Perdomo Silva, Vivek Y Reddy: Ultrasound-Based Renal Sympathetic Denervation as Adjunctive Upstream Therapy During Atrial Fibrillation Ablation: The ULTRA-HFIB Pilot. JACC Clin Electrophysiol January 2026.
Taisei Kobayashi and Herbert D Aronow.: Lower Extremity Angiography and Interventions. CATHSAP, American College of Cardiology 2026.
Sana Rehman, Tayyab Shah, Yousuf Shah, Andrew Schwartz, Kriyana P Reddy, Lauren Glassmoyer, Taisei Kobayashi, Allison Tsao, Ashwin Nathan, Jay S Giri, Alexander C Fanaroff: Enrollment of Older Patients, Women, and Historically Underrepresented Racial and Ethnic Groups in Pulmonary Embolism Trials: A Systematic Review. J Soc Cardiovasc Angiogr Interv October 2025.
Tung M, Kobayashi T, Swaminathan RV, Cohen DL, Feldman DN, Fulton B.: Renal Denervation: A Review of Current Devices, Techniques, and Evidence. Interv Cardiol Clin. 14(2): 225-234, April 2025 Notes: https://doi.org/10.1016/j.iccl.2024.11.008.
Shah T, Zhang Z, Shah H, Fanaroff AC, Nathan AS, Parise H, Lutz J, Sugeng L, Bellumkonda L, Redfors B, Omerovic E, Petrie MC, Vora AN, Fiorilli PN, Kobayashi T, Ahmad Y, Forrest JK, Giri JS, Herrmann HC, Lansky AJ.: Effect of Sodium-Glucose Cotransporter-2 Inhibitors on the Progression of Aortic Stenosis. JACC Cardiovasc Interv. 18(6): 738-748, March 2025 Notes: doi: 10.1016/j.jcin.2024.11.036. PMID: 39985508.
Nathan AS, Kennedy KF, Reddy KP, Fanaroff AC, Kolansky DM, Kobayashi TJ, Khatana SAM, Dayoub EJ, Eberly L, Rao SV, Mehran R, Bhatt D, Yeh RW, Spertus JA, Giri J.: Variation in Likelihood of Undergoing Percutaneous Coronary Intervention for ST-Segment-Elevation Myocardial Infarction Among US Hospitals. J Am Heart Assoc 16(2): 109-14, March 2025 Notes: https://doi.org/10.1016/0306-3623(85)90045-x.
Pliakos E, Glassmoyer L, Kobayashi T, Pugliese S, Shankar H, Matthai W, Khandhar S, Giri J, Nathan A.: Economic Analysis of Catheter-Directed Thrombolysis for Intermediate-Risk Pulmonary Embolism. Catheter Cardiovasc Interv 105(2): 326-334, February 2025 Notes: https://doi.org/10.1002/ccd.31280.
Faggioni M, Giri J, Glassmoyer L, Kobayashi T.: A Rational Approach to the Treatment of Acute Pulmonary Embolism. Annu Rev Med 76(1), January 2025 Notes: doi: 10.1146/annurev-med-050423-085457. PMID: 39745937.
Ramadan OI, Yang L, Shultz K, Genovese E, Damrauer SM, Wang GJ, Secemsky EA, Treat-Jacobson DJ, Womeodu RJ, Fakorede FA, Nathan AS, Eberly LA, Julien HM, Kobayashi TJ, Groeneveld PW, Giri J, Fanaroff AC.: Racial, Socioeconomic, and Geographic Disparities in Preamputation Vascular Care for Patients With Chronic Limb-Threatening Ischemia. Circ Cardiovasc Qual Outcomes 18(1): e010931, January 2025 Notes: https://doi.org/10.1161/circoutcomes.124.010931.