Edward Cantu III, MD, MSCE

faculty photo
Professor of Surgery at the Hospital of the University of Pennsylvania
Active Surgeon, Penn Presbyterian Medical Center, Philadelphia, PA
Active Surgeon, Pennsylvania Hospital, Philadelphia, PA
Attending Surgeon, Hospital of the University of Pennsylvania, Philadelphia, PA
Director of Ex Vivo Lung Perfusion , Hospital of the University of Pennsylvania, Philadelphia, PA
Director of Lung Transplant Research, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA
Director ILD Service Line, Hospital of the University of Pennsylvania, Philadelphia, PA
Department: Surgery

Contact information
Hospital of the University of Pennsylvania
Department of Surgery
Division of Cardiovascular Surgery
3400 Spruce Street
6 Silverstein
Philadelphia, PA 19104-4283
Office: 215-615-6582
Fax: 215-349-5798
Education:
BA
Harvard University, Cambridge, MA, 1994.
MD
Columbia University College of Physicians and Surgeons, New York, NY, 2000.
MS (Clinical Epidemiology )
Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 2015.
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Description of Clinical Expertise

Lung Transplantation

Description of Research Expertise

Lung donor risk predicion
Donor optimization
Ex Vivo Lung Perfusion
Prediction of lung PGD
Mechanisms of PGD
Therapeutics for PGD

Selected Publications

Hunt ML, Cantu E.: Primary graft dysfunction after lung transplantation. Curr Opin Organ Transplant 28: 180-186, Jun 2023.

Anderson MR, Cantu E, Shashaty M, Benvenuto L, Kalman L, Palmer S, Singer JP, Gallop R, Diamond JM, Hsu J, Localio AR, Christie JD.: Body Mass Index and Cause-specific Mortality after Lung Transplantation in the United States. Ann Am Thorac Soc Mar 2023.

Shiraishi K, Shah PP, Morley MP, Loebel C, Santini GT, Katzen J, Basil MC, Lin SM, Planer JD, Cantu E, Jones DL, Nottingham AN, Li S, Cardenas-Diaz FL, Zhou S, Burdick JA, Jain R, Morrisey EE.: Biophysical forces mediated by respiration maintain lung alveolar epithelial cell fate. Cell 186: 1478-1492, Mar 2023.

Schnellinger EM, Cantu E, Kimmel SE, Szymczak JE.: A Conceptual Model for Sources of Differential Selection in Lung Transplant Allocation. Ann Am Thorac Soc 2023.

McGinniss JE, Whiteside SA, Deek RA, Simon-Soro A, Graham-Wooten J, Oyster M, Brown MD, Cantu E, Diamond JM, Li H, Christie JD, Bushman FD, Collman RG: The lung allograft microbiome associates with pepsin, inflammation, and primary graft dysfunction. American Journal of Respiratory & Critical Care Medicine 206(12): 1508-1521, Dec. 15 2022 Notes: Epub Sept. 14, 2022.

McGinniss JE, Whiteside SA, Deek RA, Simon-Soro A, Graham-Wooten J, Oyster M, Brown MD, Cantu E, Diamond JM, Li H, Christie JD, Bushman FD, Collman RG.: The Lung Allograft Microbiome Associates with Pepsin, Inflammation, and Primary Graft Dysfunction. Am J Respir Crit Care Med 206: 1508-1521, Dec 2022.

Cantu E, Diamond JM, Cevasco M, Suzuki Y, Crespo M, Clausen E, Dallara L, Ramon CV, Harmon MT, Bermudez C, Benvenuto L, Anderson M, Wille KM, Weinacker A, Dhillon GS, Orens J, Shah P, Merlo C, Lama V, McDyer J, Snyder L, Palmer S, Hartwig M, Hage CA, Singer J, Calfee C, Kukreja J, Greenland JR, Ware LB, Localio R, Hsu J, Gallop R, Christie JD: Contemporary trends in PGD incidence, outcomes, and therapies. Journal of Heart & Lung Transplantation 41(12): 1839-1849, Dec. 2022 Notes: Epub Aug. 31, 2022.

Koons B, Suzuki Y, Cevasco M, Bermudez CA, Harmon MT, Dallara L, Ramon CV, Nottingham A, Ganjoo N, Diamond JM, Christie JD, Localio AR, Cantu E.: Cryoablation in lung transplantation: Its impact on pain, opioid use, and outcomes. JTCVS Open 13: 444-456, Nov 2022.

Schnellinger EM, Cantu E, Schaubel DE, Kimmel SE, Stephens-Shields AJ: Clinical impact of a modified lung allocation score that mitigates selection bias. Journal of Heart & Lung Transplantation 41(11): 1590-1600, Nov. 2022 Notes: Epub Aug. 7, 2022.

Crnkovic S, Valzano F, Flie├čer E, Gindlhuber J, Thekkekara Puthenparampil H, Basil M, Morley MP, Katzen J, Gschwandtner E, Klepetko W, Cantu E, Wolinski H, Olschewski H, Lindenmann J, Zhao YY, Morrisey EE, Marsh LM, Kwapiszewska G: Single-cell transcriptomics reveals skewed cellular communication and phenotypic shift in pulmonary artery remodeling. JCI Insight 7(20): e153471, Oct. 24 2022.

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Last updated: 05/17/2023
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