Benjamin J Wilkins, MD, PhD

faculty photo
Assistant Professor of Pathology and Laboratory Medicine at the Children's Hospital of Philadelphia
Department: Pathology and Laboratory Medicine

Contact information
Children's Hospital of Philadelphia
Main Hospital 5NW08
3401 Civic Center Blvd
Philadelphia, PA 19104
Office: 267-426-0174
Fax: 215-590-1736
Education:
B.S. (Biology)
John Carroll University, Cleveland, Ohio, 1998.
Ph.D. (Molecular and Developmental Biology)
University of Cincinnati College of Medicine, Cincinnati, Ohio, 2004.
M.D.
University of Cincinnati College of Medicine, Cincinnati, Ohio, 2006.
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Description of Clinical Expertise

I am a board-certified pediatric anatomic pathologist. My clinical interest and expertise is in the diagnosis of pediatric gastrointestinal and liver disease.

Description of Research Expertise

My research focus is on collaborative studies that characterize phenotypes related to gastrointestinal and liver diseases in animal models (mouse and zebrafish) and human tissues. Current studies include multiple projects related to eosinophilic esophagitis; analysis of a potential role for Thrombospondin-2 as a modifier of Alagille syndrome liver disease; and clinicopathologic study of bile duct paucity in neonatal cholestasis. My prior laboratory research focused primarily on the role of CIRH1A in liver development using zebrafish as a model system, and mechanisms whereby the recessive CIRH1A R565W mutation found in patients with North American Indian Childhood Cirrhosis lead to congenital biliary disease.

Selected Publications

Klein J, Wilkins BJ, Verma R, Muir AB.: Collagenous Gastritis Masquerading as Eosinophilic Gastritis. ACG Case Rep J 8: e00527, Feb 2021.

Kotch C, Friedman DF, Wilkins BJ, Samelson-Jones BJ.: Conservative Management of Alloimmune Hemolysis and Cholestasis With Extreme Laboratory Abnormalities. Pediatrics 147: e20193367, Feb 2021.

Wilkins BJ, Russo P: Biliary Atresia. Liver Biopsy in Children. Ranganathan S (eds.). 2021 Notes: Invited book chapter, submitted.

Shenoy A, Wilkins BJ, Russo P: Childhood Liver Diseases and Metabolic Disorders. Practical Interpretation of Liver Biopsy 2021 Notes: Invited book chapter, in press.

Graham KD, López SH, Sengupta R, Shenoy A, Schneider S, Wright CM, Feldman M, Furth E, Valdivieso F, Lemke A, Wilkins BJ, Naji A, Doolin EJ, Howard MJ, Heuckeroth RO.: Robust, 3-Dimensional Visualization of Human Colon Enteric Nervous System Without Tissue Sectioning. Gastroenterology 158: 2221-2235, Jun 2020.

Gilbert Melissa A, Schultz-Rogers Laura, Rajagopalan Ramakrishnan, Grochowski Christopher M, Wilkins Benjamin J, Biswas Sawona, Conlin Laura K, Fiorino Kristin N, Dhamija Radhika, Pack Michael A, Klee Eric W, Piccoli David A, Spinner Nancy B: Protein-elongating mutations in MYH11 are implicated in a dominantly inherited smooth muscle dysmotility syndrome with severe esophageal, gastric, and intestinal disease. Human mutation 41: 973-982, Jan 2020.

MacFarland Suzanne P, Zelley Kristin, Katona Bryson W, Wilkins Benjamin J, Brodeur Garrett M, Mamula Petar: Gastrointestinal Polyposis in Pediatric Patients. Journal of pediatric gastroenterology and nutrition 69(3): 273-280, Sep 2019.

Kennedy Katie, Muir Amanda B, Grossman Andrew, Brown-Whitehorn Terri, Cianferoni Antonella, Spergel Jonathan M, Furuta Glenn T, Wilkins Benjamin J, Shuker Michele, Ruffner Melanie A: Modified oral enteric-coated budesonide regimens to treat pediatric eosinophilic gastroenteritis, a single center experience. The journal of allergy and clinical immunology. In practice 7(6): 2059-2061, Jul - Aug 2019.

Chatterji Priya, Williams Patrick A, Whelan Kelly A, Samper Fernando C, Andres Sarah F, Simon Lauren A, Parham Louis R, Mizuno Rei, Lundsmith Emma T, Lee David Sm, Liang Shun, Wijeratne Hr Sagara, Marti Stefanie, Chau Lillian, Giroux Veronique, Wilkins Benjamin J, Wu Gary D, Shah Premal, Tartaglia Gian G, Hamilton Kathryn E: Posttranscriptional regulation of colonic epithelial repair by RNA binding protein IMP1/IGF2BP1. EMBO reports 20(6): e47074, Jun 2019.

Spergel Jonathan M, Elci Okan U, Muir Amanda B, Liacouras Chris A, Wilkins Benjamin J, Burke Deirdre, Lewis Megan O, Brown-Whitehorn Terri, Cianferoni Antonella: Efficacy of Epicutaneous Immunotherapy in Children With Milk-Induced Eosinophilic Esophagitis. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 18(2): S1542-3565(19)30524-5, May 2019.

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Last updated: 03/26/2021
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