Francis Edward Marchlinski, MD
Richard T. and Angela Clark President's Distinguished Professor
Director of Electrophysiology, University of Pennsylvania Health System
Consulting Staff in Department of MedicineDivision of Cardiology, Penn Medicine Princeton Health
Department: Medicine
Contact information
The Pavilion
One Convention Avenue
2 Pavilion - City Side
Electrophysiology Suite
Philadelphia, PA 19104-4283
One Convention Avenue
2 Pavilion - City Side
Electrophysiology Suite
Philadelphia, PA 19104-4283
Office: (215) 662-6005
Fax: (215) 662-2879
Fax: (215) 662-2879
Publications
Links
Search PubMed for articles
Penn Health Profile
2021 peer reviewed original research publications
Cardiovascular Division Faculty
2020 Peer Reviewed Original research publications
Search PubMed for articles
Penn Health Profile
2021 peer reviewed original research publications
Cardiovascular Division Faculty
2020 Peer Reviewed Original research publications
Education:
B.S. (Premedicine, Magna Cum Laude )
Pennsylvania State University, State College, 1973.
M.D.
University of Pennsylvania School of Medicine, 1976.
Permanent linkB.S. (Premedicine, Magna Cum Laude )
Pennsylvania State University, State College, 1973.
M.D.
University of Pennsylvania School of Medicine, 1976.
Description of Research Expertise
Electrophysiology of the human atria and ventriclesMechanism of supraventricular and ventricular arrhythmias
Anatomic and electrophysiologic substrate of atrial and ventricular arrhythmias.
Catheter ablative therapy in atrial and ventricular arrhythmias
Device therapy in management of ventricular arrhythmias
Arrhythmogenic cardiomyopathy and cardiac arrhythmias
Description of Clinical Expertise
Diagnosis and management of supraventricular and ventricular arrhythmiasSubstrate mapping and catheter ablation of atrial and ventricular arrhythmias.
Pacemaker therapy in management of bradycardias
Implantable defibrillator therapy in treating ventricular arrhythmias
Management of atrial and ventricular arrhythmias in arrhythmogenic cardiomyopathy (ARVC)
Evaluation and treatment of genetically determined arrhythmia syndromes
Evaluation of patients with unexplained syncope
Selected Publications
Shirai Y, Liang JJ, Santangeli P, Supple GE, Riley MP, Garcia FC, Lin D, Dixit S, Callans DJ, Marchlinski FE, Frankel DS, Schaller RD: Catheter Ablation of Premature Ventricular Complexes with Low Intraprocedural Burden Guided Exclusively by Pace-mapping. J Cardiovasc Electrophysio 30(11): 2326, November 2019.Kodali S, Shirai Y, Muser D, Callans DJ, Marchlinski FE, Santangeli P: Ventricular Tachycardia in Nonischemic Cardiomyopathy:Anteroseptal Versus Inferolateral Origin Based On ICD Ventricular Electrogram Timing. J Cardiovasc Electrophysiol 30(11): 2334-2343, November 2019.
Maheshwari A, Shirai Y, Hyman MC, Arkles JS, Santangeli P, Schaller RD, Supple GE, Nazarian S, Lin D, Dixit S, Callans DJ, Marchlinski FE, Frankel DS: Septal Versus Mitral Isthmus Ablation for Treatment of Mitral Annular Flutter. JACC Clin Electrophysiol October 2019.
Ustunkaya T, Desjardins B, Wedan R, Chahal CAA, Zimmerman SL, Saju N, Zahid S, Sharma A, Han Y, Trayanova N, Marchlinski FE, Calkins H, Tandri H, Nazarian S. : Epicardial Conduction Speed, Electrogram Abnormality, and Computed Tomography Attenuation Associations in Arrhythmogenic Right Ventricular Cardiomyopathy JACC Clin Electrophysio 5(10): 1158, Oct 2019.
Briceño DF, Liang JJ, Shirai Y Markman TM, Enriquez A, Lin A, Santangeli P, Riley MP, Schaller RD, Nazarian S, Lin D, Kumareswaran R, Arkles JS, Hyman MC, Supple GE, Frankel DS, Garcia FC, Callans DJ, Marchlinski FE, Dixit S.: Clinical and Electrophysiological Characteristics of Idiopathic Ventricular Arrhythmias Originating from the Slow Pathway Region Heart Rhythm 16(9): 142, September 2019.
Kuo L, Shirai Y, Muser D, Liang JJ, Castro SA, Santangeli P, Schaller RD, Supple GE, Lin D, Nazarian S, Dixit S, Callans DJ, Marchlinski FE, Frankel DS. : Comparison of the Arrhythmogenic Substrate Between Men and Women with Nonischemic Cardiomyopathy Heart Rhythm 16(9): 141, September 2019.
Kodali S, Shirai Y, Callans DJ, Zado ES, Marchlinski FE, Santangeli P: Usefulness of ICD Electrograms Analysis to Distinguish Endocardial Versus Epicardial Ventricular Tachycardia in Arrhythmogenic Right Ventricular Cardiomyopathy. J Cardiovasc Electrophysiol 30(9): 1526, September 2019.
Yang J, Brunnquell M, Liang JJ, Callans DJ, Garcia FC, Lin D, Frankel DS, Kay J, Marchlinski FE, Tzou W, Sauer WH, Liu B, Ruckdeschel ES, Collins K, Santangeli P, Nguyen DT. : Long term Follow-up after Ventricular Tachycardia Ablation in Patients with Congenital Heart Disease. J Cardiovasc Electrophysiol 30(9): 1560, September 2019.
Zielonka B, Kim YY, Supple GE, Partington SL, Ruckdeschel ES, Marchlinski FE, Frankel DS: Improvement in Ventricular Function with Rhythm Control of Atrial Arrhythmias May Delay the Need for Atrioventricular Valve Surgery in Adults with Congenital Heart Disease. Congenit Heart Dis August 2019.
Shirai Y, Liang JJ, Santangeli P, Supple GE, Riley MP, Garcia FC, Lin D, Dixit S, Callans DJ, Marchlinski FE, Frankel DS, Schaller RD : Catheter Ablation of Premature Ventricular Complexes with Low Intraprocedural Burden Guided Exclusively by Pace-mapping J Cardiovasc Electrophysiol August 2019.
Marrouche NF, Wazni O, McGann C, Greene T, Dean JM, Dagher L, Kholmovski KE, Mansour M, Marchlinski FE, Wilber D, Hendricks G, Mahnkopf C, Wells D, Jais P, Sanders P, Brachmann J, Bax JJ, Morrison-de Boer L, Deneke T, Calkins H, Sohns C, Akoum N: DECAAF-II investigators: Effect of MRI-guided fibrosis ablation vs conventional catheter ablation on atrial arrhythmia recurrence in patients with persistent A-fib: The DECAAF II Randomized Clinical Trial. JAMA 21;327(23): 2296-2305, June 2022.
Arceluz MR, Liuba I, Tschabrunn CM, Frankel DS, Santangeli P, Supple GS, Schaller RD, Garcia FC, Callans DJ, Guandalini Gustavos S. Walsh K, Nazarian S, Zado ES, Marchlinski FE. : "Sinus Rhythm QRS Amplitude and Fractionation in Patients with Non-Ischemic Cardiomyopathy to Identify Ventricular Tachycardia Substrate and Location" Heart Rhythm 19(2): 187-194, Feb 2022.
Thind M, Arceluz MR, Lucena-Padros I, Kubala M, Mirwais M, Bode W, Cerantola M, Sugrue A, Van Niekerk C, Vigdor A, Patel NA, AlSalem AB, Zado ES, Kumareswaran R, Lin D, Arkles JS, Garcia FC, Guandalini GS, Markman TM, Riley MP, Deo R, Schaller RD, Nazarian S, Dixit S, Epstein AE, Supple GE, Frankel DS, Tschabrunn CM, Santangeli P, Callans DJ, Hyman MC, Marchlinski FE: Identifying Origin of Nonpulmonary Vein Triggers Using 2 Stationary Linear Decapolar Catheters: A Novel Algorithm. JACC Clin Electrophysiol Nov 2023.
marrouche NF, Wazni O, McGann C, Greene T, Dean JM, Dagher L, Kholmovski E, Mansour M, Marchlinski F, Wilber D, Hindricks G, Mahnkopf C, Wells D, Jais P, Sanders P, Brachmann J, Bax JJ, Morrison-de Boer L, Deneke T, Calkins H, Sohns C, Akoum N;: Effect of MRI-Guided Fibrosis Ablation vs Conventional Catheter Ablation on Atrial Arrhythmia Recurrence in Patients With Persistent A-Fib: The DECAAF II. Randomized Clinical Trial. J JAMA june 2022.
Thind M, Oraii A, Chaumont C, Arceluz MR, Sekigawa M, Yogasundaram H, Sugrue A, Mirwais M, AlSalem AB, Zado ES, Guandalini GS, Markman TM, Deo R, Schaller RD, Dixit S, Epstein AE, Supple GE, Tschabrunn CM, Santangeli P, Callans DJ, Hyman MC, Nazarian S, Frankel DS, Marchlinski FE: Predictors of Non-Pulmonary vein triggers for atrial fibrillation: A clinical risk score. Heart Rhythm(24), Jan 2024.
Marchlinski FE, Oraii A, Muser D. : "Anticoagulation for atrial fibrillation in patients with intermediate stroke risk: is the grey zone becoming less grey?" Eur Heart J 45(1): 67-69, Jan 2024.
Chaumont C, Tschabrunn CM, Oraii A, Zado ES, Yogasundaram H, Sekigawa M, Markman T, Deo R, Dixit S, Epstein AE, Garcia FC, Lin D, Riley MP, Supple GE, Hyman MC, Nazarian S, Callans DJ, Anselme F, Frankel DS, Marchlinski FE. : Long-term freedom from ventricular arrhythmias in ARVC with endocardial only ablation: origin, and ablation outcomes of ventricular premature depolarizations initiating ventricular fibrillation. Heart Rhythm Jun 2024.
566. Boersma LV, Natale A, Haines D, DeLurgio D, Sood N, Marchlinski F, Calkins H, Hoyt RH, Sanders P, Irwin J, Packer D, Mittal S, Durrani S, DiBiase L, Sangrigoli R, Tada H, Sasano T, Tomita H, Yamane T, Kuck KH, Wazni O, Tarakji K, Cerkvenik J, van Bragt KA, Abeln BGS, Verma A.: Prevalence, timing, and impact of early recurrence of atrial tachyarrhythmias after pulsed field ablation: A secondary analysis of the PULSED AF trial. Heart Rhythm Jun 2024.