Francis Edward Marchlinski, MD

faculty photo
Richard T. and Angela Clark President's Distinguished Professor
Department: Medicine

Contact information
HUP
3400 Spruce Street
9 Founders Pavilion
Philadelphia, PA 19104-4283
Office: (215) 662-6005
Fax: (215) 662-2879
Education:
B.S. (Premedicine, Magna Cum Laude )
Pennsylvania State University, State College, 1973.
M.D.
University of Pennsylvania School of Medicine, 1976.
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Description of Research Expertise

Electrophysiology of the human atria and ventricles
Mechanism of supraventricular and ventricular arrhythmias
Anatomic and electrophysiologic substrate of atrial and ventricular arrhythmias.
Catheter ablative therapy in atrial and ventricular arrhythmias
Device therapy in management of ventricular arrhythmias
Arrhythmogenic cardiomyopathy and cardiac arrhythmias

Description of Clinical Expertise

Diagnosis and management of supraventricular and ventricular arrhythmias
Substrate mapping and catheter ablation of atrial and ventricular arrhythmias.
Pacemaker therapy in management of bradycardias
Implantable defibrillator therapy in treating ventricular arrhythmias
Management of atrial and ventricular arrhythmias in arrhythmogenic cardiomyopathy (ARVC)
Evaluation and treatment of genetically determined arrhythmia syndromes
Evaluation of patients with unexplained syncope

Selected Publications

Shirai Y, Liang JJ, Santangeli P, Supple GE, Riley MP, Garcia FC, Lin D, Dixit S, Callans DJ, Marchlinski FE, Frankel DS, Schaller RD: Catheter Ablation of Premature Ventricular Complexes with Low Intraprocedural Burden Guided Exclusively by Pace-mapping. J Cardiovasc Electrophysio 30(11): 2326, November 2019.

Kodali S, Shirai Y, Muser D, Callans DJ, Marchlinski FE, Santangeli P: Ventricular Tachycardia in Nonischemic Cardiomyopathy:Anteroseptal Versus Inferolateral Origin Based On ICD Ventricular Electrogram Timing. J Cardiovasc Electrophysiol 30(11): 2334-2343, November 2019.

Maheshwari A, Shirai Y, Hyman MC, Arkles JS, Santangeli P, Schaller RD, Supple GE, Nazarian S, Lin D, Dixit S, Callans DJ, Marchlinski FE, Frankel DS: Septal Versus Mitral Isthmus Ablation for Treatment of Mitral Annular Flutter. JACC Clin Electrophysiol October 2019.

Ustunkaya T, Desjardins B, Wedan R, Chahal CAA, Zimmerman SL, Saju N, Zahid S, Sharma A, Han Y, Trayanova N, Marchlinski FE, Calkins H, Tandri H, Nazarian S. : Epicardial Conduction Speed, Electrogram Abnormality, and Computed Tomography Attenuation Associations in Arrhythmogenic Right Ventricular Cardiomyopathy JACC Clin Electrophysio 5(10): 1158, Oct 2019.

BriceƱo DF, Liang JJ, Shirai Y Markman TM, Enriquez A, Lin A, Santangeli P, Riley MP, Schaller RD, Nazarian S, Lin D, Kumareswaran R, Arkles JS, Hyman MC, Supple GE, Frankel DS, Garcia FC, Callans DJ, Marchlinski FE, Dixit S.: Clinical and Electrophysiological Characteristics of Idiopathic Ventricular Arrhythmias Originating from the Slow Pathway Region Heart Rhythm 16(9): 142, September 2019.

Kuo L, Shirai Y, Muser D, Liang JJ, Castro SA, Santangeli P, Schaller RD, Supple GE, Lin D, Nazarian S, Dixit S, Callans DJ, Marchlinski FE, Frankel DS. : Comparison of the Arrhythmogenic Substrate Between Men and Women with Nonischemic Cardiomyopathy Heart Rhythm 16(9): 141, September 2019.

Kodali S, Shirai Y, Callans DJ, Zado ES, Marchlinski FE, Santangeli P: Usefulness of ICD Electrograms Analysis to Distinguish Endocardial Versus Epicardial Ventricular Tachycardia in Arrhythmogenic Right Ventricular Cardiomyopathy. J Cardiovasc Electrophysiol 30(9): 1526, September 2019.

Yang J, Brunnquell M, Liang JJ, Callans DJ, Garcia FC, Lin D, Frankel DS, Kay J, Marchlinski FE, Tzou W, Sauer WH, Liu B, Ruckdeschel ES, Collins K, Santangeli P, Nguyen DT. : Long term Follow-up after Ventricular Tachycardia Ablation in Patients with Congenital Heart Disease. J Cardiovasc Electrophysiol 30(9): 1560, September 2019.

Zielonka B, Kim YY, Supple GE, Partington SL, Ruckdeschel ES, Marchlinski FE, Frankel DS: Improvement in Ventricular Function with Rhythm Control of Atrial Arrhythmias May Delay the Need for Atrioventricular Valve Surgery in Adults with Congenital Heart Disease. Congenit Heart Dis August 2019.

Shirai Y, Liang JJ, Santangeli P, Supple GE, Riley MP, Garcia FC, Lin D, Dixit S, Callans DJ, Marchlinski FE, Frankel DS, Schaller RD : Catheter Ablation of Premature Ventricular Complexes with Low Intraprocedural Burden Guided Exclusively by Pace-mapping J Cardiovasc Electrophysiol August 2019.

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Last updated: 11/11/2019
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