Jonathan A. Mitchell, Ph.D.

faculty photo
Research Assistant Professor of Pediatrics
Department: Pediatrics

Contact information
Roberts Center for Pediatric Research
2716 South Street, Room 14363
Philadelphia, PA 19146
Office: 267-426-1473
Education:
BSc (Hons) (Physiology)
University of Glasgow, 2004.
MSc (Human Nutrition)
University of Glasgow, 2006.
PhD (Exercise Science)
University of South Carolina, 2011.
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Description of Research Expertise

The overarching goal of my research is to optimize physical growth and body composition in early life to help prevent the leading chronic diseases in adulthood (cardiovascular diseases, cancers and osteoporosis). I specifically investigate obesity and bone accrual, focusing on energetic behaviors and genes that contribute to fat mass and bone mass in childhood.

Selected Publications

Qian F, Wang S, Mitchell J, McGuffog L, Barrowdale D, Leslie G, Oosterwijk JC, Chung WK, Evans DG, Engel C, Kast K, Aalfs CM, Adank MA, Adlard J, Agnarsson BA, Aittomäki K, Alducci E, Andrulis IL, Arun BK, Ausems MGEM, Azzollini J, Barouk-Simonet E, Barwell J, Belotti M, Benitez J, Berger A, Borg A, Bradbury AR, Brunet J, Buys SS, Caldes T, Caligo MA, Campbell I, Caputo SM, Chiquette J, Claes KBM, Margriet Collée J, Couch FJ, Coupier I, Daly MB, Davidson R, Diez O, Domchek SM, Donaldson A, Dorfling CM, Eeles R, Feliubadaló L, Foretova L, Fowler J, Friedman E, Frost D, Ganz PA, Garber J, Garcia-Barberan V, Glendon G, Godwin AK, Gómez Garcia EB, Gronwald J, Hahnen E, Hamann U, Henderson A, Hendricks CB, Hopper JL, Hulick PJ, Imyanitov EN, Isaacs C, Izatt L, Izquierdo Á, Jakubowska A, Kaczmarek K, Kang E, Karlan BY, Kets CM, Kim SW, Kim Z, Kwong A, Laitman Y, Lasset C, Hyuk Lee M, Won Lee J, Lee J, Lester J, Lesueur F, Loud JT, Lubinski J, Mebirouk N, Meijers-Heijboer HEJ, Meindl A, Miller A, Montagna M, Mooij TM, Morrison PJ, Mouret-Fourme E, Nathanson KL, Neuhausen SL, Nevanlinna H, Niederacher D, Nielsen FC, Nussbaum RL, Offit K, Olah E, Ong KR, Ottini L, Park SK, Peterlongo P, Pfeiler G, Phelan CM, Poppe B, Pradhan N, Radice P, Ramus SJ, Rantala J, Robson M, Rodriguez GC, Schmutzler RK, Hutten Selkirk CG, Shah PD, Simard J, Singer CF, Sokolowska J, Stoppa-Lyonnet D, Sutter C, Yen Tan Y, Teixeira RM, Teo SH, Terry MB, Mads T, Marc T, Amanda ET, Katherine MT, Nadine T, van Asperen CJ, van Engelen K, van Rensburg EJ, Wang-Gohrke S, Wappenschmidt B, Weitzel JN, Yannoukakos D; GEMO Study Collaborators; HEBON; EMBRACE, Greene MH, Rookus MA, Easton DF, Chenevix-Trench G, Antoniou AC, Goldgar DE, Olopade OI, Rebbeck TR, Huo D: Height and Body Mass Index as Modifiers of Breast Cancer Risk in BRCA1/2 Mutation Carriers: A Mendelian Randomization Study. Journal of the National Cancer Institute Oct 2018 Notes: Accepted, in press.

Quante M, Mariani S, Weng J, Marinac CR, Kaplan ER, Rueschman M, Mitchell JA, James P, Hipp JA, Cespedes Feliciano EM, Wang R, Redline S: Zeitgebers and their association with rest-activity patterns. Chronobiology International Sept 2018 Notes: (in press, accepted Sept 20th).

Marinac CR, Quante M, Mariani S, Weng J, Redline S, Cespedes Feliciano EM, Hipp JA, Wang D, Kaplan ER, James P, Mitchell JA: Associations Between Timing of Meals, Physical Activity, Light Exposure, and Sleep with Body Mass Index in Free-Living Adults. Journal of Physical Activity and Health Sept 2018 Notes: (in press, accepted Sept 18th).

Roy SM, Fields DA, Mitchell JA, Hawkes CP, Kelly A, Wu GD, DeRusso PA, Elovitz MA, Ford E, Drigo D, Zemel BS, McCormack SE: Body Mass Index is a Better Indicator of Body Composition than Weight-for-Length at Age 1 Month. The Journal of Pediatrics Aug 2018 Notes: In press (accepted Aug 8th 2018).

Mitchell JA, Chesi A, McCormack SE, Cousminer DL, Kalkwarf HJ, Lappe J, Gilsanz V, Oberfield SE, Shepherd JA, Kelly A, Zemel BS, Grant SFA: Multi-dimensional bone density phenotyping reveals new insights in to genetic regulation of the pediatric skeleton. Journal of Bone and Mineral Research 33(5): 812-821, May 2018.

Mitchell JA, Chesi A, McCormack SE, Cousminer DL, Kalkwarf HJ, Lappe J, Gilsanz V, Oberfield SE, Shepherd JA, Kelly A, Grant SFA, Zemel BS: Physical Activity and Bone Accretion: Isotemporal Modeling and Genetic Interactions. Medicine and Science in Sports and Exercise 50(5): 977-986, May 2018.

Mostoufi-Moab S, Kelly A, Mitchell JA, Baker J, Zemel BS, Brodsky J, Long J, Leonard MB: Changes in Pediatric DXA Measures of Musculoskeletal Outcomes and Correlation with Quantitative CT Following Treatment of Acute Lymphoblastic Leukemia Bone. Bone Apr 2018 Notes: Accepted, in press.

Cousminer DL, Mitchell JA, Chesi A, Roy SM, Kalkwarf HJ, Lappe JM, Gilsanz V, Voight BF, Oberfield SE, Shepherd JA, Kelly A, McCormack SE, Zemel BS, Grant SFA: Genetically determined later puberty impacts lowered bone mineral density in childhood and adulthood. Journal of Bone and Mineral Research 33(3), Mar 2018.

Cespedes Feliciano EM, Quante M, Weng J, Mitchell JA, James P, Marinac CR, Mariani S, Redline S, Kerr J, Godbole S, Mantiega A, Wang D, Hipp JA: Actigraphy-Derived Daily Rest-Activity Patterns and Body Mass Index in Community-Dwelling Adults. SLEEP 40(12), Dec 2017.

Murray K, Godbole S, Natarajan L, Full K, Hipp JA, Glanz K, Mitchell JA, Laden F, James P, Quante M, Kerr J: The Relations between Sleep, Time of Physical Activity, and Time Outdoors Among Adult Women. PLoS One 12(9): e0182013, Sep 2017.

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Last updated: 10/17/2018
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