Jonathan A. Mitchell, Ph.D.

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Research Assistant Professor of Pediatrics
Department: Pediatrics

Contact information
Roberts Center for Pediatric Research
2716 South Street, Room 14363
Philadelphia, PA 19146
Office: 267-426-1473
BSc (Hons) (Physiology)
University of Glasgow, 2004.
MSc (Human Nutrition)
University of Glasgow, 2006.
PhD (Exercise Science)
University of South Carolina, 2011.
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Description of Research Expertise

The overarching goal of my research is to optimize physical growth and body composition in early life to help prevent the leading chronic diseases in adulthood (cardiovascular diseases, cancers and osteoporosis). I specifically investigate obesity and bone accrual, focusing on energetic behaviors and genes that contribute to fat mass and bone mass in childhood.

Selected Publications

Mostoufi-Moab S, Kelly A, Mitchell JA, Baker J, Zemel BS, Brodsky J, Long J, Leonard MB: Changes in Pediatric DXA Measures of Musculoskeletal Outcomes and Correlation with Quantitative CT Following Treatment of Acute Lymphoblastic Leukemia Bone. Bone Apr 2018 Notes: Accepted, in press.

Cespedes Feliciano EM, Quante M, Weng J, Mitchell JA, James P, Marinac CR, Mariani S, Redline S, Kerr J, Godbole S, Mantiega A, Wang D, Hipp JA: Actigraphy-Derived Daily Rest-Activity Patterns and Body Mass Index in Community-Dwelling Adults. SLEEP 40(12), Dec 2017.

Mitchell JA, Chesi A, McCormack SE, Cousminer DL, Kalkwarf HJ, Lappe J, Gilsanz V, Oberfield SE, Shepherd JA, Kelly A, Zemel BS, Grant SFA: Multi-dimensional bone density phenotyping reveals new insights in to genetic regulation of the pediatric skeleton. Journal of Bone and Mineral Research Dec 2017 Notes: In press.

Mitchell JA, Chesi A, McCormack SE, Cousminer DL, Kalkwarf HJ, Lappe J, Gilsanz V, Oberfield SE, Shepherd JA, Kelly A, Grant SFA, Zemel BS: Physical Activity and Bone Accretion: Isotemporal Modeling and Genetic Interactions. Medicine and Science in Sports and Exercise Nov 2017 Notes: In press.

Cousminer DL, Mitchell JA, Chesi A, Roy SM, Kalkwarf HJ, Lappe JM, Gilsanz V, Voight BF, Oberfield SE, Shepherd JA, Kelly A, McCormack SE, Zemel BS, Grant SFA: Genetically determined later puberty impacts lowered bone mineral density in childhood and adulthood. Journal of Bone and Mineral Research Oct 2017 Notes: In Press.

Murray K, Godbole S, Natarajan L, Full K, Hipp JA, Glanz K, Mitchell JA, Laden F, James P, Quante M, Kerr J: The Relations between Sleep, Time of Physical Activity, and Time Outdoors Among Adult Women. PLoS One 12(9): e0182013, Sep 2017.

McCormack SE, Cousminer DL, Chesi A, Mitchell JA, Roy SM, Kalkwarf HJ, Lappe JM, Gilsanz V, Oberfield SE, Shepherd JA, Kelly A, Grant SFA, Zemel BS: Association between linear growth and bone accrual: a longitudinal assessment of a diverse cohort of children and adolescents. JAMA Pediatrics 171(9): e171769, Sep 2017.

Mitchell JA, Quante M, Godbole S, James P, Hipp JA, Marinac CR, Mariani S, Cespedes Feliciano EM, Glanz K, Laden F, Wang R, Weng J, Redline S, Kerr J: Variation in actigraphy-estimated rest-activity patterns by demographic factors. Chronobiology International 34(8): 1042-1056, Aug 2017.

Manousaki D, Dudding T, Haworth S, Hsu Y, Liu C, Medina-Gómez C, Voortman T, van der Velde N, Melhus H, Robinson-Cohen C, Cousminer DL, Nethander M, Vandenput L, Noordam R, Forgetta V, Greenwood CMT, Biggs ML, Psaty BM, Rotter JI, Zemel BS, Mitchell JA, Taylor B, Lorentzon M, Karlsson M, Jaddoe VVW, Tiemeier H, Campos-Obando N, Franco OH, Utterlinden AG, Broer L, van Schoor NM, Ham AC, Arfan Ikram M, Karasik D, de Mutsert R, Rosendaal FR, den Heijer M, Wang TJ, Lind L, Orwoll ES, Mook-Kanamori DO, Michaëlsson K, Kestenbaum B, Ohlsson C, Mellström D, CPGM de Groot L, Grant SFA, Kiel DP, Zillikens MC, Rivadeneira F, Sawcer S, Timpson NJ, Richards BJ: Low Frequency Synonymous Coding Variation in CYP2R1 has Large Effects on Vitamin D Level and Risk of Multiple Sclerosis. American Journal of Human Genetics 101(2): 227-238, Aug 2017.

Chesi A, Mitchell JA, Kalkwarf HJ, Bradfield JP, Lappe J, Cousminer DL, Roy SM, McCormack SE, Gilsanz V, Oberfield SE, Hakonarson H, Shepherd JA, Kelly A, Zemel B, Grant SFA: A Genome-Wide Association Study Identifies Two Sex-specific Loci, at SPTB and IZUMO3, Influencing Pediatric Bone Mineral Density at Multiple Skeletal Sites. Journal of Bone and Mineral Research 32(6): 1274-1281, Jun 2017.

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Last updated: 04/25/2018
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