Jonathan A. Mitchell, Ph.D.

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Assistant Professor of Pediatrics (Gastroenterology, Hepatology and Nutrition)
Member, Metabolism, Nutrition and Physical Development Research Affinity Group, Children's Hospital of Philadelphia
Member, Mobile Health Research Affinity Group, Children's Hospital of Philadelphia
Faculty Member, Chronobiology and Sleep Institute, University of Pennsylvania
Co-Director, Digital Health Innovation Core, Center for Human Phenomic Science, Children's Hospital of Philadelphia
Member, Institute for Translational Medicine and Therapeutics, University of Pennsylvania School of Medicine
Core Faculty Member, Center for Pediatric and Clinical Effectiveness, Children's Hospital of Philadelphia
Co-Director, Pediatric Sleep and Circadian Research Affinity Group, Children’s Hospital of Philadelphia
Department: Pediatrics

Contact information
Children's Hospital of Philadelphia
Division of Gastroenterology, Hepatology and Nutrition
Roberts Center for Pediatric Research
2716 South Street, Room 14363
Philadelphia, PA 19146
Office: 267-426-1473
BSc (Hons) (Physiology)
University of Glasgow, Glasgow, UK, 2004.
MSc (Human Nutrition)
University of Glasgow, Glasgow, UK, 2006.
PhD (Exercise Science)
University of South Carolina, Columbia, SC, 2011.
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Description of Research Expertise

The overarching goal of my research is to help prevent chronic diseases in later life, by focusing on energetic behaviors (sleep, diet, and physical activity) and their impact on body composition during growth and development. My lab includes the Unit for Energetic Behavior Research that conducts multidisciplinary epidemiological studies, using sensors to measure locomotor activity, advanced imaging to measure body composition, detailed nutritional assessment to measure energy intake and dietary behavior, geospatial methods to measure the neighborhood environment, and DNA collection for gene-behavior interaction analyses. In addition, my lab’s Unit for Optimizing Behavioral Interventions uses the Multiphase Optimization Strategy framework to design digital interventions to improve energetic behavior profiles in childhood.

Selected Publications

Fair M, Decker J, Fiks AG, Mayne S, Morales KH, Williamson AA, Mitchell JA: Optimizing Intervention Components for Sleep Promotion in Children in the Context of Obesity Prevention: The SLEEPY 2.0 Study Protocol. Frontiers in Sleep Sept 2023 Notes: In press, accepted Sept 13th 2023.

Zemel BS, Shepherd JA, Grant SFA, Lappe JM, Oberfield SE, Mitchell JA, Winer KK, Kelly A, Kalkwarf HJ: Reference Ranges for Body Composition Indices by Dual Energy X-ray Absorptiometry from the Bone Mineral Density in Childhood Study Cohort. The American Journal of Clinical Nutrition Aug 2023 Notes: In press, accepted Aug 15th 2023.

Mayne S, DiFiore G, Hannan C, Nwokeji U, Tam V, Filograna C, Martin T, South E, Mitchell JA, Glanz K, Fiks A: Using Mobile Methods to Assess Time-Varying Home and Neighborhood Environmental Exposures Related to Adolescent Sleep. Sleep Health 9(3): 331-338, Jun 2023.

Husain S, Morales KH, Williamson AA, Mayne SL, Fiks AG, Basner M, Dinges DF, Zemel BS, Mitchell JA: The Neighborhood Environment and Sleep Health in Adolescents. Sleep Health Page: doi: 10.1016, Jun 2023 Notes: epub ahead of print.

Hitt TA, Hershey J, Olivos-Stewart D, Forth E, Stuart F, Garren P, Mitchell JA, Hawkes CP, Willi SM, Gettings JM: The Impact of Fear of Hypoglycaemia on Sleep in Adolescents with Type I Diabetes. Diabetic Medicine 14(1): e15066, Feb 2023.

Basner M, Smith MG, Jones CC, Ecker AJ, Howard K, Schneller V, Cordoza M, Kaizi-Lutu M, Park-Chavar S, Stahn AC, Dinges DF, Shou H, Mitchell JA, Bhatnagar A, Smith T, Smith AE, Stopforth CK, Yeager R, Keith R: Associations of Bedroom PM2.5, CO2, Temperature, Humidity and Noise with Sleep: an Observational Actigraphy Study. Sleep Health 9(7): 253-263, Feb 2023.

Marquet O, Hirsch, JA, Kerr J, Jankowska MM, Mitchell J, Hart JE, Laden F, Hipp JA, James P: GPS-Based Activity Space Exposure to Greenness and Walkability is Associated With Increased Accelerometer-Based Physical Activity. Environment International 165: 107317, Jun 2022.

Elkhatib Smidt SD, Ghorai A, Taylor SC, Gehringer B, Dow HC, Langer A, Rawot E, Zhang J, Mitchell JA, Rader DJ, Almasy L, Brodkin ES, Bucan M: The Relationship Between Autism Spectrum and Sleep-Wake Traits. Autism Research 15(4): 641-652, Apr 2022.

Elkhatib Smidt SD, Gooneratne N, Brodkin ES, Bucan M, Mitchell JA: Sufficient Sleep Duration in Autistic Children and the Role of Physical Activity. Autism 26(4): 814-826, Apr 2022.

Vajravelu MA, Hitt TA, Mak N, MS, Edwards A, Mitchell JA, Schwartz L, Kelly A, Amaral S: Text Messages and Financial Incentives for Physical Activity: Insights from Virtual Group Interviews of Adolescents with Prediabetes and Type 2 Diabetes. Journal of Medical Internet Research Diabetes 7(2): e33082, Feb 2022.

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Last updated: 09/15/2023
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