Jonathan A. Mitchell, Ph.D.

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Assistant Professor of Pediatrics
Member, Metabolism, Nutrition and Physical Development Research Affinity Group, Children's Hospital of Philadelphia
Member, Mobile Health Research Affinity Group, Children's Hospital of Philadelphia
Faculty Member, Chronobiology and Sleep Institute, University of Pennsylvania
Co-Director, Digital Health Innovation Core, Center for Human Phenomic Science, Children's Hospital of Philadelphia
Member, Resource Review Committee, Center for Human Phenomic Science, Children's Hospital of Philadelphia
Member, Institute for Translational Medicine and Therapeutics, University of Pennsylvania School of Medicine
Core Faculty Member, Center for Pediatric and Clinical Effectiveness, Children's Hospital of Philadelphia
Department: Pediatrics

Contact information
Children's Hospital of Philadelphia
Division of Gastroenterology, Hepatology and Nutrition
Roberts Center for Pediatric Research
2716 South Street, Room 14363
Philadelphia, PA 19146
Office: 267-426-1473
BSc (Hons) (Physiology)
University of Glasgow, Glasgow, UK, 2004.
MSc (Human Nutrition)
University of Glasgow, Glasgow, UK, 2006.
PhD (Exercise Science)
University of South Carolina, Columbia, SC, 2011.
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Description of Research Expertise

The overarching goal of my research is to help prevent chronic diseases in later life, by focusing on energetic behaviors (sleep, diet, and physical activity) and their impact on body composition during growth and development. My lab includes the Unit for Energetic Behavior Research that conducts multidisciplinary epidemiological studies, using sensors to measure locomotor activity, advanced imaging to measure body composition, detailed nutritional assessment to measure energy intake and dietary behavior, geospatial methods to measure the neighborhood environment, and DNA collection for gene-behavior interaction analyses. In addition, my lab’s Unit for Optimizing Behavioral Interventions uses the Multiphase Optimization Strategy framework to design digital interventions to improve energetic behavior profiles in childhood.

Selected Publications

Hitt TA, Hershey J, Olivos-Stewart D, Forth E, Stuart F, Garren P, Mitchell JA, Hawkes CP, Willi SM, Gettings JM: The Impact of Fear of Hypoglycaemia on Sleep in Adolescents with Type I Diabetes. Diabetic Medicine 14(1): e15066, Feb 2023.

Basner M, Smith MG, Jones CC, Ecker AJ, Howard K, Schneller V, Cordoza M, Kaizi-Lutu M, Park-Chavar S, Stahn AC, Dinges DF, Shou H, Mitchell JA, Bhatnagar A, Smith T, Smith AE, Stopforth CK, Yeager R, Keith R: Associations of Bedroom PM2.5, CO2, Temperature, Humidity and Noise with Sleep: an Observational Actigraphy Study. Sleep Health Feb 2023 Notes: Accepted.

Mayne S, DiFiore G, Hannan C, Nwokeji U, Tam V, Filograna C, Martin T, South E, Mitchell JA, Glanz K, Fiks A: Using Mobile Methods to Assess Time-Varying Home and Neighborhood Environmental Exposures Related to Adolescent Sleep. Sleep Health Page: doi: 10.1016, Jan 2023 Notes: epub ahead of print.

Marquet O, Hirsch, JA, Kerr J, Jankowska MM, Mitchell J, Hart JE, Laden F, Hipp JA, James P: GPS-Based Activity Space Exposure to Greenness and Walkability is Associated With Increased Accelerometer-Based Physical Activity. Environment International 165: 107317, Jun 2022.

Elkhatib Smidt SD, Ghorai A, Taylor SC, Gehringer B, Dow HC, Langer A, Rawot E, Zhang J, Mitchell JA, Rader DJ, Almasy L, Brodkin ES, Bucan M: The Relationship Between Autism Spectrum and Sleep-Wake Traits. Autism Research 15(4): 641-652, Apr 2022.

Elkhatib Smidt SD, Gooneratne N, Brodkin ES, Bucan M, Mitchell JA: Sufficient Sleep Duration in Autistic Children and the Role of Physical Activity. Autism 26(4): 814-826, Apr 2022.

Vajravelu MA, Hitt TA, Mak N, MS, Edwards A, Mitchell JA, Schwartz L, Kelly A, Amaral S: Text Messages and Financial Incentives for Physical Activity: Insights from Virtual Group Interviews of Adolescents with Prediabetes and Type 2 Diabetes. Journal of Medical Internet Research Diabetes 7(2): e33082, Feb 2022.

Patel M, McCormick A, Mitchell JA, Lin KY, Farmer J, Rummey C, Perlman S, Delatycki M, Wilmot G, Mathews K, Yoon G, Hoyle C, Subramony SH, Zesiewicz T, Lynch DR, McCormack SE: Body Mass Index and Height in the Friedreich Ataxia Clinical Outcome Measures Study. Neurology Genetics 7(6): e638, Dec 2021.

Grgic O, Gazzara MR, Chesi A, Medina-Gomez C, Cousminer DL, Mitchell JA, Prijatelj V, Shevroja E, McCormack SE, Kalkwarf HJ, Lappe JM, Gilsanz V, Oberfield SE, Shepherd JA, Kelly A, Faucz FR, Feelders RA, de Jong FH, Uitterlinden AG, Visser JA, Ghanem LR, Wolvius EB, Hofland LJ, Stratakis CA, Zemel BS, Barash Y, Grant SFA, Rivadeneira F: Splicing of CYP11B1 is Involved in Adrenal Steroidogenesis and Skeletal Maturation of Children. Communications Biology 4(1): 1274, Nov 2021.

Mayne S, Morales K, Williamson AA, Grant SFA, Fiks AG, Dinges DF, Zemel BS, Mitchell JA: Associations of the Residential Built Environment with Adolescent Sleep Outcomes. SLEEP 44(6): zsaa276, Jun 2021.

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Last updated: 03/31/2023
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