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Tara C Gangadhar, MD

Tara C Gangadhar, MD

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Assistant Professor of Medicine at the Hospital of the University of Pennsylvania
Department: Medicine

Contact information
3400 Civic Center Blvd.
South Pavilion, 7th Floor
Philadelphia, PA 19104
Office: 215-662-7907
Fax: 215-662-4646
Education:
BA (Anthropology)
Columbia University, 2000.
MD (Internal Medicine)
New York University School of Medicine, 2004.
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Description of Clinical Expertise

Melanoma
Cutaneous malignancies
Gastroinitestinal malignancies

Description of Research Expertise

Melanoma
Immune therpay
Targeted therapy
Phase I trials
Combination therapy
Experimental therapeutics
Pharmacology

Selected Publications

Twyman-Saint Victor Christina, Rech Andrew J, Maity Amit, Rengan Ramesh, Pauken Kristen E, Stelekati Erietta, Benci Joseph L, Xu Bihui, Dada Hannah, Odorizzi Pamela M, Herati Ramin S, Mansfield Kathleen D, Patsch Dana, Amaravadi Ravi K, Schuchter Lynn M, Ishwaran Hemant, Mick Rosemarie, Pryma Daniel A, Xu Xiaowei, Feldman Michael D, Gangadhar Tara C, Hahn Stephen M, Wherry E John, Vonderheide Robert H, Minn Andy J: Radiation and dual checkpoint blockade activate non-redundant immune mechanisms in cancer. Nature 520(7547): 373-7, Apr 2015.

Wang Tao, Xiao Min, Ge Yingbin, Krepler Clemens, Belser Eric, Lopez-Coral Alfonso, Xu Xiaowei, Zhang Gao, Azuma Rikka, Liu Qin, Liu Rui, Li Ling, Amaravadi Ravi K, Xu Wei, Karakousis Giorgos, Gangadhar Tara C, Schuchter Lynn M, Lieu Melissa, Khare Sanika, Halloran Molly B, Herlyn Meenhard, Kaufman Russel E: BRAF Inhibition Stimulates Melanoma-Associated Macrophages to Drive Tumor Growth. Clinical cancer research : an official journal of the American Association for Cancer Research 21(7): 1652-64, Apr 2015.

Robert Caroline, Ribas Antoni, Wolchok Jedd D, Hodi F Stephen, Hamid Omid, Kefford Richard, Weber Jeffrey S, Joshua Anthony M, Hwu Wen-Jen, Gangadhar Tara C, Patnaik Amita, Dronca Roxana, Zarour Hassane, Joseph Richard W, Boasberg Peter, Chmielowski Bartosz, Mateus Christine, Postow Michael A, Gergich Kevin, Elassaiss-Schaap Jeroen, Li Xiaoyun Nicole, Iannone Robert, Ebbinghaus Scot W, Kang S Peter, Daud Adil: Anti-programmed-death-receptor-1 treatment with pembrolizumab in ipilimumab-refractory advanced melanoma: a randomised dose-comparison cohort of a phase 1 trial. Lancet 384(9948): 1109-17, Sep 2014.

Braunstein Inbal, Gangadhar Tara C, Elenitsas Rosalie, Chu Emily Y: Vemurafenib-induced interface dermatitis manifesting as radiation-recall and a keratosis pilaris-like eruption. Journal of Cutaneous Pathology Jun 2014.

Gangadhar Tara C, Vonderheide Robert H: Mitigating the toxic effects of anticancer immunotherapy. Nature Reviews Clinical Oncology 11(2): 91-9, Feb 2014.

Tara C Gangadhar, Fecher LA, Miller C, Karakousis G, Vonderheide R, Xu G, and Schuchter LM: Melanoma. Abeloff’s Clinical Oncology. Elsevier, 5th Edition, 2014.

Hamid Omid, Robert Caroline, Daud Adil, Hodi F Stephen, Hwu Wen-Jen, Kefford Richard, Wolchok Jedd D, Hersey Peter, Joseph Richard W, Weber Jeffrey S, Dronca Roxana, Gangadhar Tara C, Patnaik Amita, Zarour Hassane, Joshua Anthony M, Gergich Kevin, Elassaiss-Schaap Jeroen, Algazi Alain, Mateus Christine, Boasberg Peter, Tumeh Paul C, Chmielowski Bartosz, Ebbinghaus Scot W, Li Xiaoyun Nicole, Kang S Peter, Ribas Antoni: Safety and tumor responses with lambrolizumab (anti-PD-1) in melanoma. The New England Journal of Medicine 369(2): 134-44, Jul 2013.

Gangadhar Tara C, Clark Joseph I, Karrison Theodore, Gajewski Thomas F: Phase II study of the Src kinase inhibitor saracatinib (AZD0530) in metastatic melanoma. Investigational New Drugs 31(3): 769-73, Jun 2013.

Tara C Gangadhar and Lynn M Schuchter: Adjuvant Therapy for Melanoma. Melanoma. William H. Sharfman (eds.). Demos Medical Publishing, 3(3): 471-484, 2012.

Sattler Martin, Reddy Mamatha M, Hasina Rifat, Gangadhar Tara, Salgia Ravi: The role of the c-Met pathway in lung cancer and the potential for targeted therapy. Therapeutic advances in medical oncology 3(4): 171-84, Jul 2011.

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Last updated: 08/12/2015
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