Paul T. Hernandez, MD

faculty photo
Assistant Professor of Clinical Surgery
Active Surgeon, Pennsylvania Hospital, Philadelphia, PA
Active Surgeon, Penn Presbyterian Medical Center, Philadelphia, PA
Attending Surgeon, Hospital of the University of Pennsylvania, Philadelphia, PA
Department: Surgery

Contact information
Division of Colon & Rectal Surgery
Penn Presbyterian Medical Center
51 North 39th Street
Ste. 266, Wright-Saunders Pavilion
Philadelphia, PA 19104
Office: 215-662-8664
Education:
BS (Chemistry (graduated with highest honors))
University of California Berkeley, Berkeley, CA, 2007.
MD
Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 2015.
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Selected Publications

Joshua I.S. Bleier, Paul Tarver Hernadnez, Lea Lowenfeld: Benign Anorectal Disorders. Sabison Textbook of Surgery: The Biologic Basis of Modern Surgical Practice. Douglas S. Tyler (eds.). Elsevier, 22: 1515-1543, August 2025.

Concors SJ, Hernandez PT, O'Brien C, DePaolo J, Murken DR, Aufhauser DD, Wang Z, Xiong Y, Krumeich L, Ge G, Beier UH, Bhatti TR, Kozikowski AP, Avelar LAA, Kurz T, Hancock WW, Levine MH.: Differential Effects of HDAC6 Inhibition Versus Knockout During Hepatic Ischemia-Reperfusion Injury Highlight Importance of HDAC6 C-terminal Zinc-finger Ubiquitin-binding Domain. Transplantation 108: 2084-2092, Oct 2024.

Neylan CJ, Kim A, Amy M, Hernandez PT.: The Epidemiology of Diverticulitis. Clin Colon Rectal Surg 38: 241-248, Oct 2024.

Hernandez P, O’Brien C, Concors SJ, Wang Z, Ge G, Hancock WW, Levine MH: The selective estrogen receptor modulator, raloxifene, is protective against renal ischemia reperfusion injury. Transplantation 106(11): 2166-2171, Nov. 1 2022 Notes: Epub Oct. 21, 2022.

Arenas DJ, Hernandez PT, Hwang J, Agarwal D, Warshauer AK, Holena DN: Appendiceal mucinous neoplasm lesion in an inflamed appendix within an inguinal hernia. Journal of Surgical Case Reports 2022(6): rjab489, June 3 2022 Notes: Case Report.

Hernandez PT, Paspulati RM, Shanmugan S: Diagnosis of anastomotic leak. Clinics in Colon & Rectal Surgery 34(6): 391-399, Nov. 23 2021.

Aufhauser D, Hernandez P, Concors S, O’Brien C, Wang Z, Murken D, Samantal A, Beier UH, Krumreich L, Bhatti TR, Wang Y, Ge G, Wang L, Cheraghlou S, Wagner FF, Holson EB, Kalin JH, Cole PA, Hancock WW, Levine MH: HDAC2 targeting stabilizes the CoREST complex in renal tubular cells and protects against renal ischemia/reperfusion injury. Scientific Reports 11(1): 9018, Apr. 27 2021.

Hernandez PT, Saur NM: Mesenteric cysts. The Mesenteric Organ in Health and Disease. Ehrenpreis ED, Alverdy JC, Wexner SD (eds.). Berlin: Springer International Publishing, Page: 445–460, 2021.

Concors SJ, Murken DR, Hernandez PT, Mahmoud NN, Paulson EC: The volume–outcome relationship in robotic proctectomy: Does center volume matter? Results of a national cohort study. Surgical Endoscopy 34(10): 4472-4480, Oct. 2020 Notes: Epub Oct. 21, 2019.

Murken DR, Straker R, Hernandez PT, Paulson EC, Bleier JI: Sacral nerve stimulation for fecal incontinence: Can demographics and diagnosis predict success? Results of a retrospective chart review Diseases of the Colon & Rectum 63(6): e340, June 2020 Notes: Presented at the American Society of Colon and Rectal Surgery 2021 Annual Meeting, San Diego, CA, Apr. 2021; abstract also published in DCR 64:5, May 2021.

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Last updated: 10/21/2025
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