Hui Li, MD, MS
Research Associate Professor of Medicine (Hematology-Oncology)
Single Genome Sequencing and SHIV Design Core Service Center, Penn Center for AIDS Research, Perelman School of Medicine, University of Pennsylvania
Department: Medicine
Contact information
422 Johnson Pavilion
3610 Hamilton Walk
Philadelphia, PA 19104-6076
3610 Hamilton Walk
Philadelphia, PA 19104-6076
Office: 205-253-7007
Fax: 215-573-8976
Lab: 215-573-6461
Fax: 215-573-8976
Lab: 215-573-6461
Education:
M.D. (Stomatology)
Capital University of Medical Sciences, Beijing, China, 1992.
M.S. (Computer Science)
University of Alabama at Birmingham, AL, 2003.
Permanent linkM.D. (Stomatology)
Capital University of Medical Sciences, Beijing, China, 1992.
M.S. (Computer Science)
University of Alabama at Birmingham, AL, 2003.
Selected Publications
Amarendra Pegu, Ling Xu, Megan E. DeMouth, Giulia Fabozzi, Kylie March, Cassandra G. Almasri, Michelle D. Cully, Keyun Wang, Eun Sung Yang, Joana Dias, Christine M. Fennessey, Jason Hataye, Ronnie R. Wei, Ercole Rao, Joseph P. Casazza, Wanwisa Promsote, Mangaiarkarasi Asokan, Krisha McKee, Stephen D. Schmidt, Xuejun Chen, Cuiping Liu, Wei Shi, Hui Geng, Kathryn E. Foulds, Shing-Fen Kao, Amy Noe, Hui Li, George M. Shaw, Tongqing Zhou, Constantinos Petrovas, John-Paul Todd, Brandon F. Keele, Jeffrey D. Lifson, Nicole Doria-Rose, Richard A. Koup, Zhi-yong Yang, Gary J. Nabel, John R. Mascola: Potent anti-viral activity of a trispecific HIV antibody in SHIV-infected monkeys. Cell Rep. 38(1), Jan 2022.H Li, C Zhao, RS Roark, F-H Lee, S Wang, A Murphy, W Ding, C Dionisos, A Singh, D Morris, R Habib, J Connell, W Liu, J Rando, J Lora1, N Chohan, Y Ding1, E Lindemuth, KO Saunders, WB Williams, BF Haynes, BH Hahn and GM Shaw: V3-glycan dependent bNAb induction in rhesus macaques infected with BG505 or CH848 SHIVs Keystone Symposia Jan 2022.
Hui Li, Chengyan Zhao, Ryan S. Roark, Fang-hua Lee, Shuyi Wang, Ajay Singh, Juliette Rando, Neha Chohan, Wenge Ding, Kevin O. Saunders, Wilton B. Williams, Barton F. Haynes, Beatrice H. Hahn and George M. Shaw: bNAb induction in rhesus macaques infected with CH848 SHIVs carrying naturally occurring deletions in V1 and E169K mutation in C-strand CHAVD Annual Retreat Oct 2021.
Jelle van Schooten, Marlies M. van Haaren, Hui Li, Laura E. McCoy, Colin Havenar-Daughton, Christopher A. Cottrell, Judith A. Burger, Patricia van der Woude, Leanne C. Helgers, Ilhan Tomris, Celia C. Labranche, David C. Montefiori, Andrew B. Ward, Dennis R. Burton, John P. Moore, Rogier W. Sanders, Shane Crotty, George M. Shaw, Marit J. van Gils: Antibody responses induced by SHIV infection are more focused than those induced by soluble native HIV-1 envelope trimers in non-human primates. PLoS Pathog. 17(8), Aug 2021.
Wilton B. Williams, R. Ryan Meyerhoff, R.J. Edwards, Hui Li, Kartik Manne, Nathan I. Nicely, Rory Henderson, Ye Zhou, Katarzyna Janowska, Katayoun Mansouri, Sophie Gobeil, Tyler Evangelous, Bhavna Hora, Madison Berry, A. Yousef Abuahmad, Jordan Sprenz, Margaret Deyton, Victoria Stalls, Megan Kopp, Allen L. Hsu, Mario J. Borgnia, Guillaume B.E. Stewart-Jones, Matthew S. Lee, Naomi Bronkema, M. Anthony Moody, Kevin Wiehe, Todd Bradley, S. Munir Alam, Robert J. Parks, Andrew Foulger, Thomas Oguin, Gregory D. Sempowski, Mattia Bonsignori, Celia C. LaBranche, David C. Montefiori, Michael Seaman, Sampa Santra, John Perfect, Joseph R. Francica, Geoffrey M. Lynn, Baptiste Aussedat, William E. Walkowicz, Richard Laga, Garnett Kelsoe, Kevin O. Saunders, Daniela Fera, Peter D. Kwong, Robert A. Seder, Alberto Bartesaghi, George M. Shaw, Priyamvada Acharya and Barton F. Haynes: Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies. Cell 184(11): 2955–2972, May 2021.
Hui Li, Shuyi Wang, Fang-Hua Lee, Ryan S Roark, Alex I Murphy, Jessica Smith, Chengyan Zhao, Juliette Rando, Neha Chohan, Yu Ding, Eunlim Kim, Emily Lindemuth, Katharine J Bar, Ivona Pandrea, Cristian Apetrei, Brandon F Keele, Jeffrey D Lifson, Mark G Lewis, Thomas N Denny, Barton F Haynes, Beatrice H Hahn, George M Shaw: New SHIVs and Improved Design Strategy for Modeling HIV-1 Transmission, Immunopathogenesis, Prevention and Cure. J Virol 95(11): e00071-21, Mar 2021.
Ryan S. Roark*, Hui Li*, Wilton B. Williams*, Hema Chug*, Rosemarie D. Mason*, Jason Gorman*, Shuyi Wang, Fang-Hua Lee, Juliette Rando, Mattia Bonsignori, Kwan-Ki Hwang, Kevin O. Saunders, Kevin Wiehe, M. Anthony Moody, Peter T. Hraber, Kshitij Wagh, Elena E. Giorgi, Ronnie M. Russell, Frederic Bibollet-Ruche, Weimin Liu, Jesse Connell, Andrew G. Smith, Julia DeVoto, Alexander I. Murphy, Jessica Smith, Wenge Ding, Chengyan Zhao, Neha Chohan, Maho Okumura, Christina Rosario, Yu Ding, Emily Lindemuth, Anya M. Bauer, Katharine J. Bar, David Ambrozak, Cara W. Chao, Gwo-Yu Chuang, Hui Geng, Bob C. Lin, Mark K. Louder, Richard Nguyen, Baoshan Zhang, Mark G. Lewis, Donald Raymond, Nicole A. Doria-Rose, Chaim A. Schramm, Daniel C. Douek, Mario Roederer, Thomas B. Kepler, Garnett Kelsoe, John R. Mascola, Peter D. Kwong, Bette T. Korber, Stephen C. Harrison, Barton F. Haynes, Beatrice H. Hahn, George M. Shaw: Recapitulation of HIV-1 Env-Antibody Coevolution in Macaques Leading to Neutralization Breadth. Science January 2021.
Hui Li, Chengyan Zhao, Ryan S. Roark, Fang-hua Lee, Shuyi Wang, Juliette Rando, Neha Chohan, Wenge Ding, Kevin O. Saunders, Wilton B. Williams, Barton F. Haynes, Beatrice H. Hahn and George M. Shaw: Characterization of V3 glycan dependent bNAb induction in SHIV CH848 10.17 and 10.17.DT infected rhesus macaques. CHAVD Annual Retreat Oct. 2020.
Hui Li,Kristen M. Marks,Andrew H. Talal,Wouter O. van Seggelen,Bisher Akil,Asa Radix,Shirish Huprikar,Andrea D. Branch,Shuyi Wang,George M. Shaw, Daniel S. Fierer: Assessing routes of hepatitis C transmission in HIV-infected men who have sex with men using single genome sequencing. PLOS ONE 15(7), July 2020.
Lawrence J. Tartaglia, Siddhant Gupte, Kevin C. Pastores, Sebastien Trott, Peter Abbink, Noe B. Mercado, Zhenfeng Li, Po-Ting Liu, Erica N. Borducchi, Abishek Chandrashekar, Esther Apraku Bondzie, Venous Hamza, Nicole Kordana, Shant Mahrokhian, Christy L. Lavine, Michael S. Seaman, Hui Li, George M. Shaw, Dan H. Barouch: Differential Outcomes following Optimization of Simian-Human Immunodeficiency Viruses from Clades AE, B, and C. J Virol. 94(10): e01860-19, May 2020.