Richard C. Crist III, PhD

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Research Assistant Professor of Genetics in Psychiatry
Department: Psychiatry

Contact information
125 South 31st St
Room 2207
Philadelphia, PA 19104
Office: 215-746-3665
BS (Biology)
Muhlenberg College, 2005.
PhD (Genetics)
Thomas Jefferson University, 2011.
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Selected Publications

Crist RC, Doyle GA, Nelson EC, Degenhardt L, Martin NG, Montgomery GW, Saxon AJ, Ling W, Berrettini WH: A polymorphism in the OPRM1 3'-untranslated region is associated with methadone efficacy in treating opioid dependence. The Pharmacogenomics Journal Dec 2016 Notes: Epub ahead of print.

Crist R C, Clarke T K: OPRD1 Genetic Variation and Human Disease. Handbook of Experimental Pharmacology: Delta Opioid Receptor Pharmacology. Emily Jutkiewicz (eds.). Springer, Dec 2016.

Crist R C, Doyle G A, Kampman K M, Berrettini W H: A delta-opioid receptor genetic variant is associated with abstinence prior to and during cocaine dependence treatment. Drug and alcohol dependence 166: 268-71, Sep 2016.

Clarke T-K, Crist R C, Ang A, Ambrose-Lanci L M, Lohoff F W, Saxon A J, Ling W, Hillhouse M P, Bruce R D, Woody G, Berrettini W H: Genetic variation in OPRD1 and the response to treatment for opioid dependence with buprenorphine in European-American females. The pharmacogenomics journal 14(3): 303-8, Jun 2014.

Crist Richard C, Berrettini Wade H: Pharmacogenetics of OPRM1. Pharmacology, biochemistry, and behavior 123: 25-33, Aug 2014.

Crist Richard C, Clarke Toni-Kim, Ang Alfonso, Ambrose-Lanci Lisa M, Lohoff Falk W, Saxon Andrew J, Ling Walter, Hillhouse Maureen P, Bruce R Douglas, Woody George, Berrettini Wade H: An intronic variant in OPRD1 predicts treatment outcome for opioid dependence in African-Americans. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 38(10): 2003-10, Sep 2013.

Crist Richard C, Ambrose-Lanci Lisa M, Zeng Angela, Yuan Cindy, Kampman Kyle M, Pettinati Helen M, Oslin David W, O'Brien Charles P, Ferraro Thomas N, Doyle Glenn A, Lohoff Falk W, Berrettini Wade H: Case-control association study of WLS variants in opioid and cocaine addicted populations. Psychiatry research 208(1): 62-6, Jun 2013.

Clarke Toni-Kim, Crist Richard C, Kampman Kyle M, Dackis Charles A, Pettinati Helen M, O'Brien Charles P, Oslin David W, Ferraro Thomas N, Lohoff Falk W, Berrettini Wade H: Low frequency genetic variants in the μ-opioid receptor (OPRM1) affect risk for addiction to heroin and cocaine. Neuroscience letters 542: 71-5, May 2013.

Crist R C, Ambrose-Lanci L M, Vaswani M, Clarke T K, Zeng A, Yuan C, Ferraro T N, Hakonarson H, Kampman K M, Dackis C A, Pettinati H M, O'Brien C P, Oslin D W, Doyle G A, Lohoff F W, Berrettini W H: Case-control association analysis of polymorphisms in the δ-opioid receptor, OPRD1, with cocaine and opioid addicted populations. Drug and alcohol dependence 127(1-3): 122-8, Jan 2013.

Crist Richard C, Roth Jacquelyn J, Waldman Scott A, Buchberg Arthur M: A conserved tissue-specific homeodomain-less isoform of MEIS1 is downregulated in colorectal cancer. PloS one 6(8): e23665, 2011.

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Last updated: 11/12/2018
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