Allan F. Simpao, MD, MBI

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Associate Professor of Anesthesiology and Critical Care at the Hospital of the University of Pennsylvania and the Children's Hospital of Philadelphia
Attending Anesthesiologist, Children's Hospital of Philadelphia
Faculty Member, Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia
Biomedical Informatics Program Co-Director, Department of Anesthesiology and Critical Care Medicine, Children's Hospital of Philadelphia
Senior Scholar, Penn Center for Perioperative Outcomes Research and Transformation, Department of Anesthesiology and Critical Care, University of Pennsylvania Perelman School of Medicine
Associate Division Chief for Research, Department of Anesthesiology and Critical Care Medicine, Division of General Anesthesiology, Children's Hospital of Philadelphia
Associate Director of Anesthesia Services, King of Prussia Hospital, Department of Anesthesiology and Critical Care Medicine, Division of General Anesthesiology, Children's Hospital of Philadelphia
Department: Anesthesiology and Critical Care

Contact information
Department of Anesthesiology and Critical Care Medicine
Children's Hospital of Philadelphia
3401 Civic Center Boulevard
Philadelphia, PA 19104
Office: 215-590-1858
Education:
BA (Biology, Psychology)
Johns Hopkins University, 1998.
BS (Computer and Information Sciences)
University of Delaware, 2003.
MD (Medicine)
Jefferson Medical College of Thomas Jefferson University, 2007.
MBI (Biomedical Informatics)
Oregon Health & Science University School of Medicine, 2015.
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Description of Clinical Expertise

Pediatric and maternal-fetal anesthesia
Ultrasound-guided regional anesthesia and vascular access
Pediatric difficult airway management

Description of Research Expertise

Pediatric and maternal-fetal anesthesiology
Anesthesia informatics and analytics
Clinical decision support systems

Selected Publications

Siddiqui A, O'Reilly-Shah V, Simpao AF, Lonsdale H: Harnessing generative artificial intelligence in pediatric anesthesia: enhancing learning, patient care, and family communication. Pediatr Anesth 2025 Notes: doi: 10.1111/pan.70005.

Kumar R, Skowno J, von Ungern-Sternberg BS, Davidson A, Xu T, Zhang J, Song X, Zhang M, Zhao P, Liu H, Jiang Y, Zuo Y, de Graaff JC, Vutskits L, Olbrecht VA, Szmuk P, Simpao AF, Tsui FR, Pratap JN, Kurth CD, Yuan I: Quantitative electroencephalogram and machine learning to predict expired sevoflurane concentration in infants. J Clin Monit Comput 2025 Notes: doi: 10.1007/s10877-025-01301-2.

Tan JM, Cannesson M, Feldman JM, Simpao AF, McGrath SP, Khanna AK, Beard JW, McGaffigan P, Cole DJ: Emerging technology and the future of perioperative care: Perspectives and recommendations from the 2023 Stoelting Conference of the Anesthesia Patient Safety Foundation. Anesth Analg 141(1): 139-51, Jul 2025 Notes: doi: 10.1213/ANE.0000000000007540.

Simpao AF, Berger JA, Matava CT: The right team for the job: dynamic, data-driven acuity scoring in pediatric perioperative care. Pediatr Anesth 35(7): 492-3, Jul 2025 Notes: doi: 10.1111/pan.15116.

Tewfik G, Minzter B, Chiao F, Zivot J, Wecksell M, Simpao AF; ASA CIIT Collaborators: Narrative review of electronic health record systems in anesthesia: benefits, risks, and medico-legal considerations in the United States of America. J Med Syst 49(1): 87, Jun 2025 Notes: doi: 10.1007/s10916-025-02221-z.

Matava CT, Yu J, Li C, Wu Y, Dear GL, Liversedge T, Thomas JJ, Winterberg AV, Simpao AF, Weintraub AY: Population-based incidence of anxiety-related behaviours during induction of general anaesthesia in children and efficacy of anxiolytic interventions: an international multicentre retrospective observational study BJA Open 14: 100411, Jun 2025 Notes: https://doi.org/10.1016/j.bjao.2025.100411.

Xie J, Gessner D, Ramaswamy P, Tan JM, Guffey P, Galvez Delgado J, Lonsdale H, Kato M, Taicher BM, Zhang D, Wecksell M, Asher D, Simpao AF, Wang E, Mudumbai S, O'Reilly-Shah V: Sharing anesthetic records with patients: an opportunity to embrace transparency. Anesthesiology 142(5): 950-1, May 2025.

Nelson O, Jones R, Moldenhauer JS, Rintoul NE, Hedrick HL, Kumar S, Helton R, Zhang B, Linder G, Simpao AF, Stricker PA, Chou ST: Cord blood for autologous transfusion in infants with congenital anomalies: volumes, sterility, and stability during storage. Transfusion 65(3), Mar 2025.

Simpao AF, Ehrenfeld JM: A joint message from the outgoing and incoming Editors-in-Chief. J Med Syst 48(1): 103, Nov 2024 Notes: https://doi.org/10.1007/s10916-024-02124-5.

Padiyath A, Pratap JN, Simpao AF: Why clinicians should care about YouCare and other wearable health devices. J Med Syst 48(1): 104, Nov 2024.

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Last updated: 06/24/2025
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