Daniel Ackerman, Ph.D.

faculty photo
Research Assistant Professor of Radiology
Department: Radiology

Contact information
Penn Image-Guided Interventions Lab
University of Pennsylvania
421 Curie Blvd
646 BRB 5
Philadelphia, PA 19104
Office: 215-573-9756
Education:
B.Sc. (Human Genetics)
University College London, 2006.
Ph.D. (Genetics)
University College London, 2012.
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Selected Publications

Nicholas R Perkons, Omar Johnson, Gabrielle Pilla, Enri Profka, Michael Mercadante, Daniel Ackerman, Terence P Gade: Functional genetic screening enables theranostic molecular imaging in cancer. Clinical Cancer Research. American Association for Cancer Research, 26(17): 4581, September 2020.

Nicholas R Perkons, Ryan M Kiefer, Michael C Noji, Mehrdad Pourfathi, Daniel Ackerman, Sarmad Siddiqui, David Tischfield, Enri Profka, Omar Johnson, Stephen Pickup, Anthony Mancuso, Austin Pantel, Michelle R Denburg, Gregory J Nadolski, Stephen J Hunt, Emma E Furth, Stephen Kadlecek, Terence PF Gade: Hyperpolarized metabolic imaging detects latent hepatocellular carcinoma domains surviving locoregional therapy. Hepatology 72(1): 140, July 2020.

Tischfield DJ, Ackerman D1, Noji M, Chen JX, Johnson O, Perkons NR, Nadolski GJ, Hunt SJ, Soulen MC, Furth EE, Gade TP: Establishment of hepatocellular carcinoma patient-derived xenografts from minimally invasive image-guided percutaneous biopsies. Scientific Reports 9(1): 166-167, July 2019.

Pantel AR, Ackerman D, Lee SC, Mankoff DA, Gade TP: Imaging Cancer Metabolism: Underlying Biology and Emerging Strategies. J Nucl Med 59(9): 1340-1349, September 2018.

Ackerman D, Tumanov A, Qiu B, Michalopoulou E, Spata M, Azzam A, Xie H, Simon MCS,Kamphorst JJ: Triglycerides Promote Lipid Homeostasis during Hypoxic Stress by Balancing Fatty Acid Saturation. Cell Reports 24(10): 2596-2605, September 2018.

Ochocki JD, Khare S, Hess M, Ackerman D, Qiu B, Daisak JI, Worth AJ, Lin N, Lee P, Xie H, Li B, Wubbenhorst B, Maguire TG, Nathanson KL, Alwine JC, Blair IA, Nissim I, Keith B, Simon MC: Arginase 2 Suppresses Renal Carcinoma Progression via Biosynthetic Cofactor Pyridoxal Phosphate Depletion and Increased Polyamine Toxicity. Cell Metabolism 27(6): 1263-1280, June 2018.

Perkons NR, Stein EJ, Nwaezeapu C, Wildenberg JC, Saleh K, Itkin-Ofer R, Ackerman D, Soulen MC, Hunt SJ, Nadolski GJ, Gade TP: Electrolytic ablation enables cancer cell targeting through pH modulation. Communications Biology 17(1), May 2018 Notes: online journal doi:10.1038/s42003-018-0047-1

Ackerman D, Noji M, Kiefer R, Perkons N, Soulden MC, Hunt SJ, Nadolski GJ, Gade TP: In Vivo Imaging of Cancer Dormancy. Tumor Metabolism Keystone Conference January 2018 Notes: Poster Presentation

Ackerman D, Tumanov A, Qiu B, Michalopoulou E, Spata M, Azzam A, Xie H, Simon MCS, Kamphorst JJ: Triglycerides Promote Lipid Homeostasis during Hypoxic Stress by Balancing Fatty Acid Saturation. Keystone Conferences New Frontiers in Understanding Tumor Metabolism January 2016 Notes: Poster Presentation

Qiu B, Ackerman D, Sanchez DJ, Li B, Ochocki JD, Grazioli A, Bobrovnikova-Marjon E, Diehl JA, Keith B, Simon MC: HIF2α-Dependent Lipid Storage Promotes Endoplasmic Reticulum Homeostasis in Clear-Cell Renal Cell Carcinoma. Cancer Discovery 5(6): 652-67, June 2015.

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Last updated: 09/02/2020
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