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Kathleen Elise O'Neill, MD, MTR
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Assistant Professor of Obstetrics and Gynecology at the Hospital of the University of Pennsylvania
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Program Director, Uterine Transplant Program, University of Pennsylvania
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Attending, Gynecology, Penn Presbyterian Medical Center, Philadelphia, PA
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Attending, Reproductive Endocrinology & Infertility, Department of Ob/Gyn, Hospital of the University of Pennsylvania, Philadelphia, PA, University of Pennsylvania
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Attending, Reproductive Endocrinology & Infertility , Department of Ob/Gyn, Pennsylvania Hospital, Philadelphia, PA
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Medical Director, Uterine Transplant Program, University of Pennsylvania
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Department: Obstetrics and Gynecology
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Contact information
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University of Pennsylvania
30 Department of Obstetrics and Gynecology
3e Division of Reproductive Endocrinology and Infertility
42 421 Curie Blvd, 1353 BRB II/III
Philadelphia, PA 19104
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30 Department of Obstetrics and Gynecology
3e Division of Reproductive Endocrinology and Infertility
42 421 Curie Blvd, 1353 BRB II/III
Philadelphia, PA 19104
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Office: (215) 898-0825
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Email:
OneilKa@uphs.upenn.edu
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OneilKa@uphs.upenn.edu
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Education:
21 7 BA 22 (Public Policy Studies) c
34 Duke University, Durham, NC, 2003.
21 7 MD 15 (Medicine) c
3e University of Michigan, Ann Arbor, MI, 2008.
21 8 MTR 23 (Translational Research) c
45 University of Pennsylvania, Philadelphia, PA, 2015.
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Permanent link21 7 BA 22 (Public Policy Studies) c
34 Duke University, Durham, NC, 2003.
21 7 MD 15 (Medicine) c
3e University of Michigan, Ann Arbor, MI, 2008.
21 8 MTR 23 (Translational Research) c
45 University of Pennsylvania, Philadelphia, PA, 2015.
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Description of Clinical Expertise
39 Mullerian anomalies and Uterus transplant71
Description of Research Expertise
61 Early embryo development, unexplained infertility, endometrium, uterus transplante 29
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e9 Jeremy Applebaum, Dan Zhao, Nawar Latif, Kathleen O'Neill : Feasibility of Near-Infrared Spectroscopy for Monitoring Tissue Oxygenation During Uterus Transplantation and Hysterectomy 40 J. Clin. Med. 14(14): 4832, July 2025.
1ca Yano Maher JC, Zelinski MB, Oktay KH, Duncan FE, Segars JH, Lujan ME, Lou H, Yun BH, Hanfling SN, Schwartz LE, Laronda MM, Halvorson LM, O'Neill KE, Gomez-Lobo V: Classification system of human ovarian follicle morphology: recommendations of the National Institute of Child Health and Human Development - sponsored ovarian nomenclature workshop. Fertil Steril 123(5):761-778, May 2025.
170 Walter JR, Richards EG, Johannesson L, Falcone T, Jungheim E, Testa G, O'Neill KE, Harvie HS: Cost-effectiveness analysis of uterus transplantation vs. gestational carrier for treatment of absolute uterine factor infertility in the United States. Fertil Steril S0015-0282(25): 00035-4, Jan 2025.
155 Johannesson L, Humphries LA, Porrett PM, Testa G, Anderson S, Walter JR, Rush M, Ferrando CA, O'Neill K, Richards EG: Classification and treatment of vaginal strictures at the donor-recipient anastomosis after uterus transplant. Fertil Steril 122(3):525-534, Sep 2024.
13e Walter JR, Johannesson L, Falcone T, Putnam JM, Testa G, Richards EG, O'Neill KE: In Vitro Fertilization Practice in Patients with Absolute Uterine Factor Undergoing Uterus Transplant in the United States. Fertil Steril 122(3):397-405, Sep 2024.
15f Herz C, Vergnet N, Tian S, Aly AH, Jolley MA, Tran N, Arenas G, Lasso A, Schwartz N, O'Neill KE, Yushkevich PA, Pouch AM: Open-source graphical user interface for the creation of synthetic skeletons for medical image analysis. J Med Imaging (Bellingham) 11(3): 036001, May 2024.
146 Johannesson L, Sawinski D, Vock DM, Kristek J, Fronek J, Richards EG, O'Neill KE, Perni U, Porrett PM, Testa G: A Multi-Institutional Report of Intermediate-Term Kidney Outcomes in Uterus Transplant Recipients. Kidney Int Rep 8(10): 2156-2159, Aug 2023.
13d Fisher SA, Grijalva M, Guo R, Johnston SA, Laurent LC, Nguyen H, Renz J, Rosario JG, Rudich S, Gregory BD, Kim J, O'Neill K: Systematic Sampling of the Female Reproductive System for Molecular Characterization. Curr Protoc 3(8): e848, Aug 2023.
174 Johannesson L, Testa G, Beshara MM, da Graca B, Walter JR, Quintini C, Latif N, Hashimoto K, Richards EG, O'Neill K: Awareness and Interest in Uterus Transplantation over Time: Analysis of Those Seeking Surgical Correction for Uterine-Factor Infertility in the US. J Clin Med 12(13): 4201, Jun 2023.
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Selected Publications
6c John R. Thorup,Sarah A. Johnston, Moe Haines, Margaret A. Rush, f8 Edwin Sedodo, Kathleen O'Neill, Ronald Drapkin, Namrata D. Udeshi, Michael A. Gillette, Steven A. Carr, Shankha Satpathy: "Microscaled Cell Surface Proteomics for Cryo-preserved Cells and Tissue Samples" Molecular & Cellular Proteomics 57 In Press, Journal Pre-proof Available online (101437), Oct 30 2025.e9 Jeremy Applebaum, Dan Zhao, Nawar Latif, Kathleen O'Neill : Feasibility of Near-Infrared Spectroscopy for Monitoring Tissue Oxygenation During Uterus Transplantation and Hysterectomy 40 J. Clin. Med. 14(14): 4832, July 2025.
1ca Yano Maher JC, Zelinski MB, Oktay KH, Duncan FE, Segars JH, Lujan ME, Lou H, Yun BH, Hanfling SN, Schwartz LE, Laronda MM, Halvorson LM, O'Neill KE, Gomez-Lobo V: Classification system of human ovarian follicle morphology: recommendations of the National Institute of Child Health and Human Development - sponsored ovarian nomenclature workshop. Fertil Steril 123(5):761-778, May 2025.
170 Walter JR, Richards EG, Johannesson L, Falcone T, Jungheim E, Testa G, O'Neill KE, Harvie HS: Cost-effectiveness analysis of uterus transplantation vs. gestational carrier for treatment of absolute uterine factor infertility in the United States. Fertil Steril S0015-0282(25): 00035-4, Jan 2025.
155 Johannesson L, Humphries LA, Porrett PM, Testa G, Anderson S, Walter JR, Rush M, Ferrando CA, O'Neill K, Richards EG: Classification and treatment of vaginal strictures at the donor-recipient anastomosis after uterus transplant. Fertil Steril 122(3):525-534, Sep 2024.
13e Walter JR, Johannesson L, Falcone T, Putnam JM, Testa G, Richards EG, O'Neill KE: In Vitro Fertilization Practice in Patients with Absolute Uterine Factor Undergoing Uterus Transplant in the United States. Fertil Steril 122(3):397-405, Sep 2024.
15f Herz C, Vergnet N, Tian S, Aly AH, Jolley MA, Tran N, Arenas G, Lasso A, Schwartz N, O'Neill KE, Yushkevich PA, Pouch AM: Open-source graphical user interface for the creation of synthetic skeletons for medical image analysis. J Med Imaging (Bellingham) 11(3): 036001, May 2024.
146 Johannesson L, Sawinski D, Vock DM, Kristek J, Fronek J, Richards EG, O'Neill KE, Perni U, Porrett PM, Testa G: A Multi-Institutional Report of Intermediate-Term Kidney Outcomes in Uterus Transplant Recipients. Kidney Int Rep 8(10): 2156-2159, Aug 2023.
13d Fisher SA, Grijalva M, Guo R, Johnston SA, Laurent LC, Nguyen H, Renz J, Rosario JG, Rudich S, Gregory BD, Kim J, O'Neill K: Systematic Sampling of the Female Reproductive System for Molecular Characterization. Curr Protoc 3(8): e848, Aug 2023.
174 Johannesson L, Testa G, Beshara MM, da Graca B, Walter JR, Quintini C, Latif N, Hashimoto K, Richards EG, O'Neill K: Awareness and Interest in Uterus Transplantation over Time: Analysis of Those Seeking Surgical Correction for Uterine-Factor Infertility in the US. J Clin Med 12(13): 4201, Jun 2023.
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