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Scott M. Damrauer, MD

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William Maul Measey Associate Professor of Surgery II
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Active Surgeon, Veterans Affairs Medical Center, Philadelphia, PA
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Active Surgeon, Penn Presbyterian Medical Center, Philadelphia, PA
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Attending Surgeon, Hospital of the University of Pennsylvania, Philadelphia, PA
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Member, Penn Cardiovascular Institute, University of Pennsylvania, Philadelphia, PA
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Member , Institute for Translational Medicine and Therapeutics, University of Pennsylvania, Philadelphia, PA
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Faculty , Center for Surgery and Health Economics, University of Pennsylvania, Philadelphia, PA
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Founding Member , Cardiovascular Outcomes, Quality and Evaluative Research Center, University of Pennsylvania, Philadelphia PA
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Associate Director, Biobank, Penn Medicine, Philadelphia, PA
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Associate Scholar , Center for Clinical Epidemiology and Biostatics, University of Pennsylvania, Philadelphia, PA
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Active Surgeon, Children’s Hospital of Philadelphia, Philadelphia, PA
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Active Surgeon, Pennsylvania Hospital, Philadelphia, PA
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Senior Fellow, Institute for Biomedical Informatics, University of Pennsylvania, Philadelphia, PA
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Core Faculty, Penn Cardiovascular Institute, University of Pennsylvania, Philadelphia, PA
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Research Associate, Population Aging Research Center (PARC), University of Pennsylvania, Philadelphia, PA
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Member, Center for Global Genomics & Health Equity, University of Pennsylvania, Philadelphia, PA
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Vice Chair for Clinical Research, Department Surgery, Perelman School of Medicine, University of Pennsylvania
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Department: Surgery
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1f Graduate Group Affiliations 8 a
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46 Contact information
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Division of Vascular Surgery
32 Hospital of the University of Pennsylvania
57 3400 Spruce Street, 14th Floor South Perelman Center
Philadelphia, PA 19104
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2e Office: 215-615-1698
32 Fax: 215-614-0463
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13 Education:
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37 Harvard College, Cambridge, MA, 1999.
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3e Harvard Medical School, Cambridge, MA, 2004.
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Selected Publications

5a5 Small AM, Yang TY, Itoh S, Thériault S, Dufresne L, Kurosawa R, Komuro I, Matsuda K, Vy HMT, Farber-Eger EH, Shaffer LL, Boulier KM, Corey KM, Ramaker ME, Laporte F, Schott JJ, Le Scouarnec S, Singh SA, Sonawane AR, Smith HA, Rafaels N; Colorado Center for Personalized Medicine; Ghouse J, Raja AA, Ostrowski SR, Sørensen E, Mikkelsen C, Pedersen OB, Erikstrup C, Ullum H; DBDS Genomic Consortium; Sveinbjornsson G, Gudbjartsson DF, Abner E; Estonian Biobank Research Team; Lee J, Ganna A, Nowak-Göttl U, Finer S; Genes & Health Research Team; Schumacher J, Maj C, Al-Kassou B, Nickenig G, Trenkwalder T, Dreβen M, Krane M, Nöthen MM, Moksnes MR, Brumpton BM, Knight S, Knowlton KU, Nadauld L, Debiec R, Musameh MD, Braund PS, Nelson CP, Czuba T, Melander O, Selvaraj MS, Koyama S, Bhukar R, Ruan Y, Ljungberg J, Damrauer SM, Levin MG, Franke A, Berger K, Ruff CT, Melloni GEM, Kamanu FK, Ito K, Do R, Loos RJF, Schunkert H, Wells QS, Shah SH, Le Tourneau T, Messika-Zeitoun D, Gignoux C, Bundgaard H, Larsson SC, Michaëlsson K, Holm H, Helgadottir A, Esko T, van Heel DA, Mathieu P, Samani NJ, Smith JG, Söderberg S, Rader DJ, Marston NA, Sabatine MS, Pasaniuc B, Cho K, Wilson PWF, O'Donnell CJ, Stefansson K, Bossé Y, et al.: Genomic and transcriptomic analyses of aortic stenosis enhance therapeutic target discovery and disease prediction. Nat Genet Dec 2025.

 15b Bowles AE, Lynch JA, Bermudez F, Shakt GE, DiNatale T, Pridgen KM, Judy RL, Levin MG, Hartmann K, Damrauer SM, Alba PR.: Detecting Bicuspid Aortic Valve From Echocardiographic Reports Using Natural Language Processing: A Veterans Affairs Study. JACC Adv 5: 102463, Dec 2025.

 16f Kim SY, Kim J, Ramos M, Haley J, Smelser D, Rao HS, Mirshahi UL, Nathanson KL, Graubard BI, Katki HA, Carey D, Stewart DR; Geisinger-Regeneron DiscovEHR Collaboration and Penn Medicine Biobank.: Genomic Ascertainment of CHEK2-Related Cancer Predisposition. JAMA Netw Open 8: e2549730, Dec 2025.

 2af Ferolito BR, Dashti H, Giambartolomei C, Peloso GM, Golden DJ, Gravel-Pucillo K, Rasooly D, Horimoto ARVR, Matty R, Gaziano L, Liu Y, Smit IA, Zdrazil B, Tsepilov Y, Costa L, Kosik N, Huffman JE, Tartaglia GG, Bini G, Proietti G, Ioannidis H, Karim MA, Hunter F, Hemani G, Butterworth AS, Di Angelantonio E, Langenberg C, Ghoussaini M, Leach AR, Liao KP, Damrauer S, Selva LE, Whitbourne S, Tsao PS, Moser J, Gaunt T, Cai T, Whittaker JC; Million Veteran Program; Casas JP, Muralidhar S, Gaziano JM, Cho K, Pereira AC.: Leveraging large-scale biobanks for therapeutic target discovery. HGG Adv 7: 100556, Dec 2025.

 19a Fanaroff AC, Coratti S, Farraday D, Norton L, Rareshide C, Zhu J, Levin MG, Damrauer SM, Giri JS, Chokshi NP, Jackson BM, Patel MS.: Effect of Gamification Plus Automated Coaching to Increase Physical Activity Among Patients With Peripheral Artery Disease: The GAMEPAD Randomized Controlled Trial. J Am Heart Assoc 14: e038921, Dec 2025.

 1d1 Sideris K, Nelson TJ, Brinker L, Gao A, Tcheandjieu C, Kyriakopoulos CP, Berlowitz D, Hull L, Ferraro JP, Agiri FY, Pridgen KM, Roblin S, Joseph J, Levin MG, Damrauer SM, Chang KM, Teerlink CC, Stehlik J, Carter S, Lynch JA.: Risk of Systemic Manifestations in Homozygous Carriers of the Transthyretin V142I Variant: A Million Veteran Program Analysis. J Am Heart Assoc 14: e044923, Dec 2025.

 113 Clark MG, Yuan S, Larsson SC, Levin MG, Woerner J, Kim D, Damrauer SM.: A sparse proteomic risk score incorporating plasma MMP12 level improves prediction of abdominal aortic aneurysm. medRxiv Dec 2025.

 150 Abramowitz SA, Hoffman-Andrews L, Zhang D, Judy R, Cappola TP, Day SM, Reza N, Owens AT, Damrauer SM, Levin MG; Penn Medicine BioBank.: Polygenic Background and Penetrance of Pathogenic Variants in Hypertrophic and Dilated Cardiomyopathies. JAMA Cardiol Dec 2025.

 ed Sokolow R, Bhattacharya A, Kissas G, Thompson EW, Beeche C, Swago S, Zhang D, Viswanadha M, Morse C, Chirinos J, Damrauer S, Verma A, Perdikaris P, Rader DJ, Witschey WR; Penn Medicine Biobank. c9 : Reduced order computational fluid dynamic simulations in the thoracic aorta are associated with disease recorded in a medical biobank. Sci. Rep. 15(1): 39203, Nov 2025.

 24f Enzan N, Miyazawa K, Koyama S, Kurosawa R, Ieki H, Yoshida H, Takechi F, Fukuyama M, Osako R, Tomizuka K, Liu X, Ozaki K, Onouchi Y; BioBank Japan Project; Matsuda K, Momozawa Y, Aburatani H, Kamatani Y, Yamaguchi T, Akazawa H, Node K, Ellinor PT, Levin MG, Damrauer SM, Voight BF, Joseph J, Sun YV, Terao C, Ninomiya T, Komuro I, Ito K.: Genome-wide analysis of heart failure yields insights into disease heterogeneity and enables prognostic prediction in the Japanese population. Nat. Commun. 16(1): 9680, Nov 2025.

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