Farzana Sayani, MD MSc

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Assistant Professor of Medicine at the Hospital of the University of Pennsylvania
Director, Penn Comprehensive Adult Thalassemia Program
Director, Penn Comprehensive Sickle Cell Program
Department: Medicine

Contact information
3rd Floor Dulles Building
3400 Spruce Street,
Philadelphia, PA 19104
Office: 215-615-6555
Fax: 215-615-6599
BSc (Cellular, Molecular and Microbial Biology)
University of Calgary, 1998.
MD (Medicine)
University of Calgary, 2001.
MSc (Haemoglobinopathies)
University College London, 2012.
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Description of Clinical Expertise

- Care of adult patients with sickle cell disease and thalassemia.
- Care of adult individuals with red cell disorders, including rare inherited red cell disorders.
- Transfusional iron overload.
- Transition of care for adult thalassemia and sickle cell patients from a pediatric to adult healthcare setting.

Description of Research Expertise

- Complications of in adults with thalassemia and sickle cell disease.
- iron overload in thalassemia.
- Improvement in care of patients with sickle cell disease and thalassemia.

Selected Publications

Peslak S and Sayani F: Hemoglobinopathies and Thalassemias. Emery and Rimoin's Principles and Practice of Medical Genetics and Genomics: Hematologic, Renal and Immunologic Disorders, 7th edition. Reed E. Pyeritz, Bruce R. Korf, Wayne W. Grody (eds.). Elsevier, 2023.

Peslak AS, Brimm-Akins A, Foxwell, AM, Iannelli M, Grande C, Breen D, Russell JE, Uritsy TJ, Sayani F. : A novel, effective, and efficient strategy for treating sickle cell vaso-occlusive events in the infusion center setting. Blood Adv Page: bloodadvances.2022007307, Aug 2022 Notes: Published online: 08/08/2022.

Matthews A, Yui J, Chiang EY, Pishko AM, Cuker A, Cucchiara BL, George D, Sayani F, Mullen MT: Cerebral infarction due to severe ADAMTS-13 deficiency with normal hematological parameters: A cause of cryptogenic stroke. J Stroke Cerebrosvasc Dis. 31(6): 106431, Jun 2022.

Roe AH, McAllister A, Kete C, Pishko A, Whitworth H, Schreiber CA, Sayani FA: Sex as an independent risk factor for venous thromboembolism in sickle cell disease: A cross-sectional study. J Womens Health Page: doi: 10.1089/jwh.2022.0046, Jun 2022 Notes: Online ahead of print.

Sayani F, Lal A, Tasian G, Al Mukaddam M, Killilea DW, Fung EB : Kidney stones in transfusion-dependent thalassemia: Prevalence and risk factors. Open Journal of Urology 125(4), April 2022.

Jean-Fellix SA, Dolin C, Triebwasser J, Sayani F, Feldman R. : Contemporary obstetric and neonatal outcomes in sickle cell disease: a retrospective cohort study. American Journal of Obstetrics and Gynecology 226(13): S215-S216, Jan 2022.

Roe AH, Lang B, McAllister A, Gaitors MC, Smith-Whitley K, Schreiber CA, Sayani F: Contraceptive use and preferences among females with sickle cell disease. Contraception 105: 42-45, Jan 2022.

Yui JC, Geara A, Sayani F. : Deferasirox-associated Fanconi syndrome in adult patients with transfusional iron overload. Vox Sang 116 (7): 793-797, Aug 2021.

Arnold T, By S, Dyvorne H, O'Halloran R, Sayani F, Desiderio L, Litt B, Stein J. : In-vivo ferumoxytol imaging and T1/T2 characterization at 64mT. International Society for Magnetic Resonance in Medicine (ISMRM), Concord, CA May 2021 Notes: "Poster Presentation" Abstract #: 1251.

Farzana Sayani: Transitioning to adult healthcare in thalassemia: Q & A with Dr. Farzana Sayani. Cooleys Anemia Foundation. Cooleys Anemia Foundation, Jan 2021 Notes: https://www.thalassemia.org/boduw/wp-content/uploads/2021/01/QA-with-Dr.-Sayani-Transitioning-to-Adult-Healthcare-in-Thalassemia.pdf.

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Last updated: 12/06/2022
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