Russell Takeshi Shinohara, Ph.D.

faculty photo
Professor of Biostatistics and Epidemiology
Senior Scholar, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania Perelman School of Medicine
Affiliated Faculty, Center for Neuromodulation in Depression and Stress (CNDS), Department of Psychiatry, University of Pennsylvania Perelman School of Medicine
Affiliated Faculty , Center for Biomedical Imaging Computing and Analytics (CBICA), University of Pennsylvania Perelman School of Medicine
Full Member , Institute for Translational Medicine and Therapeutics (ITMAT), University of Pennsylvania Perelman School of Medicine
Senior Fellow, Institute for Biomedical Informatics (IBI), University of Pennsylvania Perelman School of Medicine
Director, Penn Statistics in Imaging and Visualization Center, University of Pennsylvania Perelman School of Medicine
Department: Biostatistics and Epidemiology

Contact information
Center for Clinical Epidemiology and Biostatistics
Department of Biostatistics, Epidemiology and Informatics
Perelman School of Medicine
University of Pennsylvania
217 Blockley Hall
423 Guardian Drive
Philadelphia, PA 19104-6021
Office: 215-746-1090
Fax: 215-573-1050
Education:
Honors BSc (Probability and Statistics)
McGill University, 2006.
MSc (Mathematics and Statistics)
McGill University, 2007.
PhD (Biostatistics)
The Johns Hopkins University, 2012.
Permanent link
 
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Selected Publications

White BR, Adepoju TE, Fisher HB, Shinohara RT, Vandekar S: Spatial Nonstationarity of Image Noise in Widefield Optical Imaging and Its Effects on Cluster-Based Inference for Resting-State Functional Connectivity. Journal of Neuroscience Methods 404: 110076, Apr 2024 Notes: doi: 10.1016/j.jneumeth.2024.110076. Epub 2024 Feb 7.

Taghvaei M, Mechanic-Hamilton DJ, Sadaghiani S, Shakibajahromi B, Dolui S, Das S, Brown C, Tackett W, Khandelwal P, Cook P, Shinohara RT, Yushkevich P, Bassett DS, Wolk DA, Detre JA; Alzheimer’s Disease Neuroimaging Initiative: Impact of white matter hyperintensities on structural connectivity and cognition in cognitively intact ADNI participants. Neurobiology of Aging 135: 79-90, Mar 2024 Notes: doi: 10.1016/j.neurobiolaging.2023.10.012. Epub 2023 Dec 12.

Skampardoni I, Nasrallah IM, Abdulkadir A, Wen J, Melhem R, Mamourian E, Erus G, Doshi J, Singh A, Yang Z, Cui Y, Hwang G, Ren Z, Pomponio R, Srinivasan D, Govindarajan ST, Parmpi P, Wittfeld K, Grabe HJ, Bülow R, Frenzel S, Tosun D, Bilgel M, An Y, Marcus DS, LaMontagne P, Heckbert SR, Austin TR, Launer LJ, Sotiras A, Espeland MA, Masters CL, Maruff P, Fripp J, Johnson SC, Morris JC, Albert MS, Bryan RN, Yaffe K, Völzke H, Ferrucci L, Benzinger TLS, Ezzati A, Shinohara RT, Fan Y, Resnick SM, Habes M, Wolk D, Shou H, Nikita K, Davatzikos C: Genetic and Clinical Correlates of AI-Based Brain Aging Patterns in Cognitively Unimpaired Individuals. JAMA Psychiatry Page: e235599, Feb 2024 Notes: doi: 10.1001/jamapsychiatry.2023.5599. Epub ahead of print.

Lemley BA, Okunowo O, Ampah SB, Wu L, Shinohara RT, Goldberg DJ, Rychik J, Glatz AC, Amaral S, O'Byrne ML: Effect of Patient Factors, Center, and Era on Fontan Timing: An observational study using the Pediatric Health Information Systems Database. American Heart Journal S0002-8703(24): 00046-2, Feb 2024 Notes: doi: 10.1016/j.ahj.2024.02.019. Epub ahead of print.

Guo J, Fathi Kazerooni A, Toorens E, Akbari H, Yu F, Sako C, Mamourian E, Shinohara RT, Koumenis C, Bagley SJ, Morrissette JJD, Binder ZA, Brem S, Mohan S, Lustig RA, O'Rourke DM, Ganguly T, Bakas S, Nasrallah MP, Davatzikos C: Integrating imaging and genomic data for the discovery of distinct glioblastoma subtypes: a joint learning approach. Scientific Reports 14(1): 4922, Feb 2024 Notes: doi: 10.1038/s41598-024-55072-y.

Wagstyl K, Adler S, Seidlitz J, Vandekar S, Mallard TT, Dear R, DeCasien AR, Satterthwaite TD, Liu S, Vértes PE, Shinohara RT, Alexander-Bloch A, Geschwind DH, Raznahan A: Transcriptional cartography integrates multiscale biology of the human cortex. Elife 12: RP86933, Feb 2024 Notes: doi: 10.7554/eLife.86933.

Bagnato F, Sati P, Hemond CC, Elliott C, Gauthier SA, Harrison DM, Mainero C, Oh J, Pitt D, Shinohara RT, Smith SA, Trapp B, Azevedo CJ, Calabresi PA, Henry RG, Laule C, Ontaneda D, Rooney WD, Sicotte NL, Reich DS, Absinta M, NAIMS Cooperative: Imaging chronic active lesions in multiple sclerosis: a consensus statement Brain Jan 2024 Notes: doi: 10.1093/brain/awae013. Epub ahead of print.

Daboul L, O'Donnell CM, Amin M, Rodrigues P, Derbyshire J, Azevedo C, Bar-Or A, Caverzasi E, Calabresi PA, Cree BA, Freeman L, Henry RG, Longbrake EE, Oh J, Papinutto N, Pelletier D, Prchkovska V, Raza P, Ramos M, Samudralwar RD, Schindler MK, Sotirchos ES, Sicotte NL, Solomon AJ, Shinohara RT, Reich DS, Sati P, Ontaneda D: A multicenter pilot study evaluating simplified central vein assessment for the diagnosis of multiple sclerosis. Multiple Sclerosis Journal 30(1): 25-34, Jan 2024 Notes: doi: 10.1177/13524585231214360. Epub 2023 Dec 13.

Emmert BE, Xie K, Conrad EC, Ghosn NJ, Bauman K, Korzun J, Kulick-Soper CV, Naveed O, Hartmann N, LaRocque JJ, Mindy Ganguly T, Gugger JJ, Raghupathi R, Gelfand MA, Davis KA, Sinha SR, Litt B, Shinohara RT, Ellis CA: Alcohol for seizure induction in the epilepsy monitoring unit Epilepsy and Behavior 150: 109572, Jan 2024 Notes: doi: 10.1016/j.yebeh.2023.109572. Epub 2023 Dec 8.

Yang, Z; Wen, J; Erus, G; Govindarajan, S; Melhem, R; Mamourian, E; Cui, Y; Srinivasan, D; Abdulkadir, A; Parmpi, P; Wittfeld, K; Grabe, H; Bulow, R; Frenzel, S; Tosun, D; Bilgel, M; An, Y; Yi, D; Marcus, D; LaMontagne, P; Benzinger, T; Heckbert, S; Austin, T; Waldstein, S; Zonderman, A; Launer, L; Sotiras, A; Espeland, M; Masters, C; Maruff, P; Fripp, J; Toga, A; O'Bryant, S; Chakravarty, M; Villeneuve, S; Johnson, S; Morris, J; Albert, M; Yaffe, K; Volzke, H; Ferrucci, L; Bryan, N; Shinohara, R; Fan, Y; Habes, M; Wolk, D; Resnick, S; Shou, H; Nasrallah, I; Davatzikos, C: Five Dominant Dimensions of Brain Aging are Identified via Deep Learning: associations with genetic, clinical and lifestyle measures. Nature Medicine In Press 2024.

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Last updated: 06/10/2024
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