Harvey E. Smith, MD

faculty photo
Associate Professor of Orthopaedic Surgery at the Hospital of the University of Pennsylvania and the Veteran's Administration Medical Center
Attending Orthopaedic Surgeon, Veteran Affairs Medical Center
Attending Orthopaedic Surgeon, Penn Presbyterian Medical Center
Attending Orthopaedic Surgeon, Hospital of the University of Pennsylvania
Attending Orthopaedic Surgeon, Pennsylvania Hospital
Department: Orthopaedic Surgery

Contact information
University of Pennsylvania School of Medicine
Department of Orthopaedic Surgery
3737 Market Street, 6th Floor
Philadelphia, PA 19104
Philadelphia, PA 19104
Office: 215-662-3340
Education:
A.B. (Chemistry & Physics)
Harvard University, 1997.
MD (Medicine)
Pennsylvania State University College of Medicine, 2002.
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Selected Publications

Matthew Fainor; Alexandra J. Baranyai; Robert Mauck; Harvey Smith; Sarah Gullbrand: Il-1beta Does Not Exacerbate Cell Death In A Large-scale Tissue-engineered Intervertebral Disc. Orthopaedic Research Society Annual Meeting 2026.

Janai A. Augustin; Kevin G. Burt; Caitlin Barrett; Harvey Smith; Robert Mauck; Thomas P. Schaer; Sarah Gullbrand: Intervertebral Disc Degeneration Correlates With Neuroinflammation In A Translational Large Animal Model. Orthopaedic Research Society Annual Meeting 2026.

Augustin JA, Burt KG, Barrett C, Fainor M, Orozco BS, Schaer TP, Smith HE, Mauck RL, Gullbrand SE: Neuroimmune Activation in a Goat Model of Intervertebral Disc Degeneration. Cells 2026.

Frehner SS, Fainor M, Dulatov G, Ringgwood R, Loftus H, Warner C, Bazaz A, Smith HE, Mauck RL, Erickson I, Gullbrand SE: A Human Progenitor Cell-Based Tissue Engineered Intervertebral Disc. Tissue Engineering Part A 2025.

Gullbrand SE, Kiapour A, Barrett C, Fainor M, Orozco BS, Hilliard R, Mauck RL, Hast MW, Schaer TP, Smith HE: Restoration of physiologic loading after engineered disc implantation mitigates immobilization-induced facet joint and paraspinal muscle degeneration. Acta Biomaterialia 192: 128-139, 2025.

Ongini, ED, Abdullah M, Engiles JB, Orozco BS, Moehl A, Peredo A, Mahindroo S, Hilliard R, Schaer TP, Mauck RL, Smith HE, Farshad M, Snedeker JG, Gullbrand SE: Annulus Repair Via Interpenetrated Non-woven Scaffold Supports Tissue Integration And Prevents Herniation. Proceedings of the Annual Meeting of the Orthopaedic Research Society 2025.

Fainor M, Bazaz A, Mauck RL, Smith HE, Gullbrand SE: Controlled Delivery of Deferoxamine in a Subcutaneous Model of Semi-Orthotopic Bone Formation. Proceedings of the Annual Meeting of the Orthopaedeic Research Society 2025.

Ongini ED, Abdullah M, Engiles JB, Orozco BS, Moehl A, Peredo A, Mahindroo S, Hilliard R, Schaer TP, Mauck RL, Smith HE, Farshad M, Snedeker JG, Gullbrand Se: Annulus Fibrosus Repair via Interpenetration of a Non-Woven Scaffold Supports Tissue Integration and Prevents Re-Herniation. JOR Spine 2025.

Fainor M, Bazaz A, Smith HE, Gullbrand SE: Assessing Cell Therapy Retention And Survival Across A Spectrum Of Intervertebral Disc Degeneration In Rabbits. Proceedings of the Annual Meeting of the Orthopaedic Research Society 2025.

Peredo AP, Tsinman TK, Bonnevie ED, Jiang X, Smith HE, Gullbrand SE, Dyment NA, Mauck RL: Developmental Morphogens Direct Human Induced Pluripotent Stem Cells Toward an Annulus Fibrosus-like Cell Phenotype. JOR Spine 7(1), 2024.

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Last updated: 05/05/2026
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