Steven Joffe, MD, MPH

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Art and Ilene Penn Professor of Medical Ethics & Health Policy
Director, Penn Fellowship in Advanced Medical Ethics, Perelman School of Medicine
Member, Abramson Cancer Center
Chief, Division of Medical Ethics, Department of Medical Ethics and Health Policy, University of Pennsylvania Perelman School of Medicine
Senior Fellow, Leonard Davis Institute
Director, Postdoctoral T32 Training Program in the Ethical, Legal and Social Implications (ELSI) of Genetics and Genomics, University of Pennsylvania Perelman School of Medicine
Senior Fellow, Penn Center for Precision Medicine
Co-Director, Cancer Control Program, Abramson Cancer Center
Interim Chair, Department of Medical Ethics and Health Policy, Perelman School of Medicine
Department: Medical Ethics and Health Policy

Contact information
423 Guardian Dr.
Blockley Hall 1413
Philadelphia, PA 19104-4884
Office: 215-898-3055
Fax: 215-573-3036
A.B. (Fine Art)
Harvard College, 1988.
M.D. (Medicine)
University of California, San Francisco School of Medicine, 1992.
M.P.H. (Epidemiology)
University of California, Berkeley, 1996.
Permanent link
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Selected Publications

Joffe S, Allen AJ, Davis JM, Koppelman E, Kornetsky SZ, Ku GMV, Miller VA, Preston J, Shah LD, Bierer BE: Establishing a global regulatory floor for children's decisions about participation in clinical research Pediatr Res January 2023 Notes: doi: 10.1038/s41390-023-02483-8. Epub ahead of print.

Glanz K, Chen J, Joffe S.: Understanding risk factors for cancer: What's new and how can it help reduce the cancer burden? Cancer Oct 2022 Notes: doi: 10.1002/cncr.34395. Epub 2022 Aug 3.

Kilbride M, Joffe S, Fernandez Lynch H. : FDA-approved drugs should be over-the-counter by default. Philadelphia Inquirer Sept 2022 Notes:

Fernandez Lynch H, Joffe S, Largent EA: ‘Is an abortion medically necessary?’ is not a question for ethicists to answer. STAT News Aug 2022 Notes:

Bezler NS, Ilowite M, London WB, Pei-Chi K, Joffe S, Mack JW: Health Literacy and Clinical Outcomes Following Hematopoietic Stem Cell Transplantation. JCO Oncol Pract Jun 2022 Notes: Drs. Joffe and Mack are co-senior authors. doi: 10.1200/OP.21.00049. Epub 2022 Jan 21.

Callahan KP, Flibotte J, Skraban C, Wild KT, Joffe S, Munson D, Feudtner C: Influence of genetic information on neonatologists’ decisions: a psychological experiment Pediatrics Mar 2022 Notes: doi: 10.1542/peds.2021-052130.

Dunkle LM, Kotloff KL, Gay CL, Áñez G, Adelglass JM, Barrat Hernández AQ, Harper WL, Duncanson DM, McArthur MA, Florescu DF, McClelland RS, Garcia-Fragoso V, Riesenberg RA, Musante DB, Fried DL, Safirstein BE, McKenzie M, Jeanfreau RJ, Kingsley JK, Henderson JA, Lane DC, Ruíz-Palacios GM, Corey L, Neuzil KM, Coombs RW, Greninger AL, Hutter J, Ake JA, Smith K, Woo W, Cho I, Glenn GM, Dubovsky F; 2019nCoV-301 Study Group: Efficacy and Safety of NVX-CoV2373 in Adults in the United States and Mexico. N Engl J Med 386(6), Feb 2022 Notes: doi: 10.1056/NEJMoa2116185. Epub 2021 Dec 15. participation cited but not by authorship.

Zacharias RL, Feldman EA, Joffe S, Lynch HF: Curbside consults in clinical medicine: empirical and liability challenges. J Law Med Ethics Jan 2022 Notes: doi: 10.1017/jme.2021.83.

Joffe S, Babiker A, Ellenberg SS, Fix A, Griffin MR, Hunsberger S, Kalil J, Levine MM, Makgoba MW, Moore RH, Tsiatis AA, Whitley R: Data and safety monitoring of COVID-19 vaccine clinical trials. J Infect Dis Page: 1995-2000, Dec 2021 Notes: Accompanied by invited editorial: Corey L. Behind the scenes heroes: the COVID-19 Vaccine Data and Safety Monitoring Board. J Infect Dis (online ahead of print, May 19, 2021; available at

El Sahly HM, Baden LR, Essink B, Doblecki-Lewis S, Martin JM, Anderson EJ, Campbell TB, Clark J, Jackson LA, Fichtenbaum CJ, Zervos M, Rankin B, Eder F, Feldman G, Kennelly C, Han-Conrad L, Levin M, Neuzil KM, Corey L, Gilbert P, Janes H, Follmann D, Marovich M, Polakowski L, Mascola JR, Ledgerwood JE, Graham BS, August A, Clouting H, Deng W, Han S, Leav B, Manzo D, Pajon R, Schödel F, Tomassini JE, Zhou H, Miller J; COVE Study Group.: Efficacy of the mRNA-1273 SARS-CoV-2 Vaccine at Completion of Blinded Phase. N Engl J Med 385: 1774-1785, Nov 2021 Notes: participation cited but not by authorship.

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Last updated: 08/31/2023
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