Steven Joffe, MD, MPH

Art and Ilene Penn Professor of Medical Ethics & Health Policy
Director, Penn Fellowship in Advanced Medical Ethics, Perelman School of Medicine
Member, Abramson Cancer Center
Chief, Division of Medical Ethics, Department of Medical Ethics and Health Policy, University of Pennsylvania Perelman School of Medicine
Senior Fellow, Leonard Davis Institute
Director, Postdoctoral T32 Training Program in the Ethical, Legal and Social Implications (ELSI) of Genetics and Genomics, University of Pennsylvania Perelman School of Medicine
Senior Fellow, Penn Center for Precision Medicine
Co-Director, Cancer Control Program, Abramson Cancer Center
Interim Chair, Department of Medical Ethics and Health Policy, Perelman School of Medicine
Department: Medical Ethics and Health Policy
Contact information
423 Guardian Dr.
Blockley Hall 1413
Philadelphia, PA 19104-4884
Blockley Hall 1413
Philadelphia, PA 19104-4884
Office: 215-898-3055
Fax: 215-573-3036
Fax: 215-573-3036
Email:
joffes@upenn.edu
joffes@upenn.edu
Publications
Education:
A.B. (Fine Art)
Harvard College, 1988.
M.D. (Medicine)
University of California, San Francisco School of Medicine, 1992.
M.P.H. (Epidemiology)
University of California, Berkeley, 1996.
Permanent linkA.B. (Fine Art)
Harvard College, 1988.
M.D. (Medicine)
University of California, San Francisco School of Medicine, 1992.
M.P.H. (Epidemiology)
University of California, Berkeley, 1996.
Selected Publications
Dember LM, Hsu JY, Mehrotra R, Cavanaugh KL, Kalim S, Charytan DM, Fischer MJ, Jhamb M, Johansen KL, Becker WC, Pellegrino B, Eneanya ND, Schrauben SJ, Pun PH, Unruh ML, Morasco BJ, Mehta M, Miyawaki N, Penfield J, Bernardo L, Brintz CE, Cheatle MD, Doorenbos AZ, Heapy AA, Keefe FJ, Krebs EE, Kuzla N, Nigwekar SU, Schmidt RJ, Steel JL, Wetmore JB, White DM, Kimmel PL, Cukor D; HOPE Consortium.: Pain Coping Skills Training for Patients Receiving Hemodialysis: The HOPE Consortium Randomized Clinical Trial. JAMA Intern Med May 2025 Notes: doi: 10.1001/jamainternmed.2025.0002.Zettler PJ, Sachs RE, Joffe S, Lynch HF: The Dangers of Decoupling Safety and Effectiveness in Drug Approval. JAMA Mar 2025 Notes: doi: 10.1001/jama.2025.2807. Epub ahead of print.
Callahan KP, Mueller R, Joffe S, Skraban C, Spinner NB, Crew K, Clapp J, Munson D, Feudtner C.: Parents' perceptions of the utility of genetic testing in the NICU. Genet Med Feb 2025 Notes: doi: 10.1016/j.gim.2025.101393. Epub ahead of print.
Dickert NW, Spiegelman D, Blumenthal-Barby JS, Graham G, Joffe S, Kahn JM, Kass NE, Kim SYH, Kerlin MP, Langford AT, Lavery JV, Matlock DD, Fenton KN, Mensah GA.: Ethical issues in implementation science: perspectives from a National Heart, Lung, and Blood Institute workshop. Implement Sci. 19(1): 77, Nov 2024.
Bierer BE, Koppelman E, Croker AK, Hosseinzadeh S, Hovinga C, Joffe S, McMillan G, Nelson R, Bucci-Rechtweg C.: Engaging children and adolescents in the design and conduct of paediatric research. Front Pediatr 12, Nov 2024.
Callahan KP, Mueller R, Crew K, Brothers K, Munson D, Joffe S, Feudtner C.: Frequency and reasons that parents decline genetic testing for critically ill neonates. Genet Med Open 2, Oct 2024.
McCoy MS, Ward M, Neergaard R, Joffe S, Szymczak JE.: Managing institutional conflicts: Stakeholder accounts of communication between conflict of interest and technology transfer offices. PLoS One 19(8): e0304519, Aug 2024 Notes: doi: 10.1371/journal.pone.0304519.
Largent EA, Joffe S, Dickert NW, Morain SR.: The ethical value of consulting community members in non-emergency trials conducted with waivers of informed consent for research. Clin Trials Jun 2024 Notes: doi: 10.1177/17407745241259360. Epub ahead of print.
Hoffman RM, Brummel S, Ziemba L, Chinula L, McCarthy K, Fairlie L, Jean-Philippe P, Chakhtoura N, Johnston B, Krotje C, Nematadzira TG, Nakayiwa F, Ndyanabangi V, Hanley S, Theron G, Violari A, João E, Correa MD Jr, Hofer CB, Navanukroh O, Aurpibul L, Nevrekar N, Zash R, Shapiro R, Stringer JSA, Currier JS, Sax P, Lockman S; IMPAACT 2010/VESTED Study Team: Weight Changes and Adverse Pregnancy Outcomes With Dolutegravir- and Tenofovir Alafenamide Fumarate-Containing Antiretroviral Treatment Regimens During Pregnancy and Postpartum. Clin Infect Dis 78(6): 1617-1628, Jun 2024 Notes: doi: 10.1093/cid/ciae001.
Dember LM, Hsu JY, Bernardo L, Cavanaugh KL, Charytan DM, Crowley ST, Cukor D, Doorenbos AZ, Edwards DA, Esserman D, Fischer MJ, Jhamb M, Joffe S, Johansen KL, Kalim S, Keefe FJ, Kimmel PL, Krebs EE, Kuzla N, Mehrotra R, Mishra P, Pellegrino B, Steel JL, Unruh ML, White DM, Yabes JG, Becker WC; HOPE Consortium.: The design and baseline characteristics for the HOPE Consortium Trial to reduce pain and opioid use in hemodialysis. Contemp Clin Trials 136(107409), Jan 2024 Notes: doi: 10.1016/j.cct.2023.107409. Epub 2023 Dec 10.