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Robert H Mach, Ph.D.

Robert H Mach, Ph.D.

faculty photo
Britton Chance Professor of Radiology
Department: Radiology
Graduate Group Affiliations

Contact information
Department of Radiology
Chemistry Building
231 S. 34th Street
Philadelphia, PA 19104
Office: 215-746-8233
B.A. (Chemistry)
State University of New York, College at Potsdam, 1978.
Ph.D. (Medical Chemistry)
State University of New York at Buffalo, Buffalo, NY, 1985.
Permanent link
Perelman School of Medicine > Faculty > Search

Selected Publications

Chen DL, Zhou D, Chu W, Herrbirch P, Engle JT, Griffin E, Jones LA, Rothfuss JM, Geraci M, Hotchkiss RS, Mach RH: Radiolabeled isatin binding to caspase-3 activation induced by anti-Fas antibody. Nuclear Medicine and Biology 39: 137-144, 2012.

Lee H, Chen, DL, Rothfuss JM, Welch MJ, Gropler RJ, Mach RH: Synthesis and evaluation of 18F-labeled PPARγ antagonists. Nuclear Medicine and Biology 39: 77-87, 2012.

Wang Y, Xu J, Xia X, Yang M, Vangveravong S, Chen J, Mach RH, Xia Y: SV119-gold nanocage conjugates: a new platform for targeting cancer cells via sigma-2 receptors Nanoscale 4: 421-424, 2012.

Luedtke RR, Mishra Y, Wang Q, Griffin SA, Bell-Horner C, Taylor M, Vangveravong S, Dillon GH, Huang R-Q, Reichert DE, Mach RH: Comparison of the binding and functional properties of two structurally different D2 dopamine receptor subtype selective compounds. ACS Chemical Neuroscience 2012 Notes: in press.

Solingapuram Sai KK, Kil KE, Tu Z, Finck BN, Rothfuss JM, Shoghi KI, Welch MJ, Gropler RJ, Mach RH: Synthesis, radiolabeling and initial in vivo evaluation of [11C]KSM-01 for imaging PPAR-α receptors. Bioorganic & Medicinal Chemistry Letters 22: 6233-6236, 2012.

Zhou Dong, Chu Wenhua, Dence Carmen S, Mach Robert H, Welch Michael J: Highly efficient click labeling using 2-[¹⁸F]fluoroethyl azide and synthesis of an ¹⁸FN-hydroxysuccinimide ester as conjugation agent. Nuclear medicine and biology 39(8): 1175-81, Nov 2012.

Mach RH and Wheeler KT: Development of Radiotracers and Fluorescent Probes for Imaging Sigma-2 Receptors In Vitro and In Vivo. Targeted Molecular Imaging. Taylor & Francis,(13), 2012.

Dehdashti F, Laforest R, Gao F, Shoghi SI, Aft RL, Nussenbaum B, Kreisel FH, Bartlett NL, Cashen A, Wagner-Johnson N, Mach RH: Assessment of cellular proliferation in tumors by positron emission tomography using [18F]ISO-1. Journal of Nuclear Medicine 2012 Notes: in press.

Luedtke RR, Perez E, Yang S-H, Liu R, Vangveravong S, Tu Z, Mach RH, Simpkins JW: Neuroprotective effects of high affinity sigma-2 receptor selective compounds. Brain Research 1441: 17-26, 2012.

Zeng C, Rothfuss J, Zhang J, Chu W, Vangveravong S, Tu Z, Pan F, Chang KC, Hotchkiss R, Mach RH: Sigma-2 ligands induce tumor cell death by multiple signaling pathways British Journal of Cancer 106: 693-701, 2012.

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Last updated: 08/25/2016
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