Christopher L. Smith, MD, PhD

Assistant Professor of Pediatrics (Cardiology) at the Children's Hospital of Philadelphia
Department: Pediatrics
Contact information
Children's Hospital of Philadelphia
3401 Civic Center Boulevard
Philadelphia, PA 19104
3401 Civic Center Boulevard
Philadelphia, PA 19104
Email:
smithc12@email.chop.edu
smithc12@email.chop.edu
Education:
BS (Biochemistry, Molecular Biology and Chemistry)
Oklahoma State University, 2004.
MD, PhD (Medical Scientist Training Program, combined MD/PhD Program)
University of Texas Southwestern Medical School, 2013.
Permanent linkBS (Biochemistry, Molecular Biology and Chemistry)
Oklahoma State University, 2004.
MD, PhD (Medical Scientist Training Program, combined MD/PhD Program)
University of Texas Southwestern Medical School, 2013.
Selected Publications
Gupta M, Krishnamurthy G, Smith CL: Central conducting lymphatic anomaly with pulmonary lymphatic dysplasia causes restrictive lung disease and chronic pleural effusion. The Lancet 16(404), November 2025 Notes: 404(10466):1989-1990. doi: 10.1016/S0140-6736(24)02355-9O'Byrne ML, Sharma P, Huang J, Smith CL, Tang J, Callahan R, Edelson JB, Dori Y, Gillespie MJ, Rome JJ, Glatz AC : Response of health-related quality of life following pediatric/congenital cardiac catheterization procedures. American Heart Journal 281(71-83), March 2025 Notes: 2025 Mar;281:71-83. doi: 10.1016/j.ahj.2024.11.017. Epub 2024 Dec 4.
Srinivasan A, Smith CL, Krishnamurthy G, Escobar F, Da Costa N, Ford B, Dori Y.: Selective Lymphatic Duct Embolization for Treatment of Thoracic Lymphatic Flow Disorders in Children: Technical Aspects and Comparison with Thoracic Duct Embolization Journal of Vascular and Interventional Radiology 36(1), January 2025 Notes: 36(1):88-98.e1. doi: 10.1016/j.jvir.2024.09.004. Epub 2024 Sep 16. PMID: 39293562.
Alkhulaifat D, Ramirez-Suarez KI, Otero HJ, Rapp JB, Srinivasan AS, Smith CL, Biko DM : Complex lymphatic anomalies Pediatric Radiology Journal January 2025 Notes: 2025 Jan 24. doi: 10.1007/s00247-025-06167-9. Online ahead of print.
Smith CL, Krishnamurthy G, Srinivasan A, Dori Y: Lymphatic interventions in congenital heart disease. Seminars in Pediatric Surgery 33(3), June 2024 Notes: Epub 2024 May 23.
Kelly B, Mohanakumar S, Ford B, Smith CL, Pinto E, Biko DM, Hjortdal VE, Dori Y: Sequential MRI Evaluation of Lymphatic Abnormalities over the Course of Fontan Completion. Radiology Cardiothoracic Imaging 6(3), June 2024.
Ramirez-Suarez KI, Schoeman S, Otero HJ, Smith CL, Biko DM: State-of-the-art imaging for children with central lymphatic disorders. Seminars in Pediatric Surgery 33(3), June 2024 Notes: Epub 2024 May 22.
Srinivasan A, Smith CL, Dori Y, Krishnamurthy G: Percutaneous procedures for central lymphatic conduction disorders. Seminars in Pediatric Surgery 33(3), June 2024 Notes: pub 2024 May 22.
Garlisi Torales LD, Sempowski BA, Krikorian GL, Woodis KM, Paulissen SM, Smith CL, Sheppard SE: Central conducting lymphatic anomaly: from bench to bedside. Journal of Clinical Investigation 134(8), April 2024.
Barak-Corren Y, Herz C, Lasso A, Dori Y, Tang J, Smith CL, Callahan R, Rome JJ, Gillespie MJ, Jolley MA, O'Byrne ML: Calculating Relative Lung Perfusion Using Fluoroscopic Sequences and Image Analysis: The Fluoroscopic Flow Calculator. Circulation Cardiovascular Interventions January 2024 Notes: Epub 2023 Dec 28.