Christopher L. Smith, MD, PhD

Assistant Professor of Pediatrics (Cardiology) at the Children's Hospital of Philadelphia
Department: Pediatrics
Contact information
Children's Hospital of Philadelphia
3401 Civic Center Boulevard
Philadelphia, PA 19104
3401 Civic Center Boulevard
Philadelphia, PA 19104
Email:
smithc12@chop.edu
smithc12@chop.edu
Education:
BS (Biochemistry, Molecular Biology and Chemistry)
Oklahoma State University, 2004.
MD, PhD (Medical Scientist Training Program, combined MD/PhD Program)
University of Texas Southwestern Medical School, 2013.
Permanent linkBS (Biochemistry, Molecular Biology and Chemistry)
Oklahoma State University, 2004.
MD, PhD (Medical Scientist Training Program, combined MD/PhD Program)
University of Texas Southwestern Medical School, 2013.
Selected Publications
Dori Y, Pinto E, Biroc L, Gillespie MJ, Callahan R, Tang J, O'Byrne ML, Ford B, Vaiyani D, DeWitt AG, Merrill D, Shinde D, Favilla E, Shustak R, Escobar FA, Krishnamurthy G, Srinivasan A, Rome JJ, Smith CL. : Percutaneous Thoracic Duct Externalization and Autotransfusion in Patients With Lymphatic Failure Due to Elevated Central Venous Pressure circulation: cardiovascular interventions September 2025 Notes: 2025 Sep 4:e015336. doi: 10.1161/CIRCINTERVENTIONS.125.015336. Online ahead of print. PMID: 40905128.El Omeiri S, Ramirez-Suarez KI, Stern J, Otero HJ, Dori Y, Biko DM, Rapp JB, Escobar F, Dewitt A, Krishnamurthy G, Srinivasan A, Smith CL. : Imaging of central lymphatics in children with Both Trisomy 21 and congenital heart disease Clinical Imaging 127(110627), September 2025 Notes: 2025 Sep 26;127:110627. doi: 10.1016/j.clinimag.2025.110627. Online ahead of print. PMID: 41027150.
O'Byrne ML, Kennedy KF, Callahan R, Dori Y, Rome JJ, Smith CL, Tang J, Gillespie MJ, Janson CM. : Evaluating Racial Disparities in Access to Common Pediatric/Congenital Transcatheter Interventions. The Journal of the American College of Cardiology Advances September 2025 Notes: 2025 Sep 23;4(11 Pt 1):102158. doi: 10.1016/j.jacadv.2025.102158. Online ahead of print. PMID: 40992238
Yuval Barak-Corren, Mudit Gupta, Yoav Dori, Jessica Tang, Christopher L. Smith, Jonathan J. Rome, Matthew J. Gillespie, Matthew A. Jolley, Michael L. O’Byrne, Ryan Callahan : Real-Time Assessment of Pulmonary Blood Flow in Pulmonary Vein Stenosis Using the Fluoroscopic Flow Calculator The official journal of the Society for Cardiovascular Angiography & Interventions 4(4), April 2025 Notes: 2025 Apr; 4(4): 102639. Published online 2025 Mar 25. doi: 10.1016/j.jscai.2025.102639 PMCID: PMC12038276.
O'Byrne ML, Sharma P, Huang J, Smith CL, Tang J, Callahan R, Edelson JB, Dori Y, Gillespie MJ, Rome JJ, Glatz AC : Response of health-related quality of life following pediatric/congenital cardiac catheterization procedures. American Heart Journal 281(71-83), March 2025 Notes: 2025 Mar;281:71-83. doi: 10.1016/j.ahj.2024.11.017. Epub 2024 Dec 4.
Yuval Barak-Corren, Mudit Gupta, Jessica Tang, Christopher L. Smith, Ryan Callahan, Yoav Dori, Jonathan J. Rome, Matthew J. Gillespie, Michael L. O’Byrne : From Text to Data: Automatically Extracting Data From Catheterization Reports Using Generative Artificial Intelligence The official journal of the Society for Cardiovascular Angiography & Interventions 4(3 Part B), March 2025 Notes: 2025 Mar; 4(3Part B): 102242. Published online 2024 Sep 3. doi: 10.1016/j.jscai.2024.102242 PMCID: PMC11993886.
Srinivasan A, Smith CL, Krishnamurthy G, Escobar F, Da Costa N, Ford B, Dori Y.: Selective Lymphatic Duct Embolization for Treatment of Thoracic Lymphatic Flow Disorders in Children: Technical Aspects and Comparison with Thoracic Duct Embolization Journal of Vascular and Interventional Radiology 36(1), January 2025 Notes: 36(1):88-98.e1. doi: 10.1016/j.jvir.2024.09.004. Epub 2024 Sep 16. PMID: 39293562.
Alkhulaifat D, Ramirez-Suarez KI, Otero HJ, Rapp JB, Srinivasan AS, Smith CL, Biko DM : Complex lymphatic anomalies Pediatric Radiology Journal January 2025 Notes: 2025 Jan 24. doi: 10.1007/s00247-025-06167-9. Online ahead of print.
Gupta M, Krishnamurthy G, Smith CL: Central conducting lymphatic anomaly with pulmonary lymphatic dysplasia causes restrictive lung disease and chronic pleural effusion. The Lancet 16(404), November 2024 Notes: 404(10466):1989-1990. doi: 10.1016/S0140-6736(24)02355-9
Smith CL, Krishnamurthy G, Srinivasan A, Dori Y: Lymphatic interventions in congenital heart disease. Seminars in Pediatric Surgery 33(3), June 2024 Notes: Epub 2024 May 23.