Amanda DiNofia, MD, MSCE

faculty photo
Assistant Professor of Clinical Pediatrics
Department: Pediatrics

Contact information
Children's Hospital of Philadelphia
Colket Translational Research Building
3501 Civic Center Boulevard, Room 3016
Philadelphia, PA 19104
Education:
B.S. (Biology)
Ursinus College, 2004.
M.D. (Medicine)
Drexel University, 2009.
M.S.C.E. (Epidemiology)
University of Pennsylvania, 2016.
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Selected Publications

H. Newman, A. Barz Leahy, Y. Li, H. Liu, R. Myers, A. DiNofia, J.G. Dolan, C. Callahan, K. Devine, L. Wray, C.H. June, S.A. Grupp, S.R. Rheingold, S.L. Maude.: CD19-targeted chimeric antigen receptor T cells in CNS relapsed acute lymphoblastic leukemia. Oral Presentation at American Society of Clinical Oncology. Virtual meeting. May 2020.

Arnold DE, Maude SL, Callahan CA, DiNofia AM, Grupp SA, Heimall JR : Subcutaneous immunoglobulin replacement following CD19-specific chimeric antigen receptor T-cell therapy for B-cell acute lymphoblastic leukemia in pediatric patients. Pediatr Blood Cancer. 7(3): e28092, Mar 2020.

R.M. Myers. S. Kadauke, Y. Li, C. Callahan, W. Gladney, J.C. Fitzgerald, L. Wray, A. Barz Leahy, D. Baniewicz, L. Motley, V. Shenoy, D.M. Barrett, D.T. Teachey, S.L. Maude, A.M. DiNofia, S. Grupp.: Risk-adapted preemptive tocilizumab decreases severe cytokine release syndrome after CTL019 CD19-targeted chimeric antigen receptor T-cell therapy for pediatric B-cell acute lymphoblastic leukemia. Oral Presentation at Transplantation and Cellular Therapy Meeting. Orlando, FL. Feb 2020.

R.M. Myers, J.C. Fitzgerald, A.M. DiNofia, L. Wray, A. Barz Leahy, Y. Li, L. Smith, E. Burrows, M. Ramos, L.S. Motley, R.N. Khan, K.D. Getz, R. Aplenc, S. Grupp, S.L. Maude.: Trends in inpatient and intensive care resource utilization after chimeric antigen receptor T cell therapy for pediatric acute lymphoblastic leukemia from 2012-2019. Oral Presentation at the 61st Annual American Society of Hematology Meeting and Exposition, Orlando, FL. Dec 2019.

A. Barz Leahy, K.J. Stanley, R. Myers, A.M. DiNofia, L. Wray, S.R. Rheingold, C. Callahan, D. Baniewicz, A.E. Barry, M.M. Patino, S.P. Hunger, S. Grupp, D.M. Barrett, S.L. Maude.: Cytogenetic characteristics and outcomes of patients receiving CTL019 CAR T cell therapy. Poster Presentation at the 61st Annual American Society of Hematology Meeting and Exposition, Orlando, FL. Dec 2019.

Pillai V, Muralidharan K, Meng W, Bagashev A, Oldridge DA, Rosenthal J, Van Arnam J, Melenhorst JJ, Mohan D, DiNofia AM, Luo M, Cherian S, Fromm JR, Wertheim G, Thomas-Tikhonenko A, Paessler M, June CH, Luning Prak ET, Bhoj VG, Grupp SA, Maude SL, Rheingold SR.: CAR T-cell therapy is effective for CD19-dim B-lymphoblastic leukemia but is impacted by prior blinatumomab therapy. Blood Adv. 3(22): 3539-3549, Nov 2019.

DiNofia AM, Maude SL: Chimeric antigen receptor T-cell clinical results in pediatric and young adult B-ALL. Hemasphere 3(4): e279, Aug 2019.

S. Kadauke, S. Maude, W. Gladney, L. Motley, V. Shenoy, C. Callahan, D. Baniewicz, D.T. Teachey, S. Grupp, A. DiNofia.: Early administration of tocilizumab for the prevention. Of grade 4 cytokine release syndrome after CD19-directed CAR T-cell therapy. Oral Presentation at the International Society of Cell & Gene Therapy, Melbourne, Australia. May 2019.

V.C. Cahen, Y. Li, C.W. Elgarten, A.M. DiNofia, J.J. Wilkes, L.E. Winestone, Y- S.V. Huang, M.M. Gramatges, K.R. Rabin, B.T. Fisher, K.D. Getz, R. Aplenc. A.E. Seif: Using administrative data to identify relapse and hematopoietic stem cell transplantation in children with acute lymphoblastic leukemia: a validation at two centers and incidence estimation in a national cohort. Oral Presentation at the 60th Annual American Society of Hematology Meeting and Exposition, San Diego, CA December 2018.

A.M. Li, G.E. Hucks, A.M. DiNofia, A.E. Seif, D.T. Teachey, D. Baniewicz, C. Callahan, C. Fasano, B. McBride, V. Gonzalez, F. Nazimuddin, D.L. Porter, S.F. Lacey, C.H. June, S.A. Grupp, S. Maude: Checkpoint inhibitors augment CD19-directed chimeric antigen receptor (CAR) T cell therapy in relapsed B-cell acute lymphoblastic leukemia. Oral Presentation at the 60th Annual American Society of Hematology Meeting and Exposition, San Diego, CA December 2018.

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Last updated: 10/23/2020
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