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John Frederick Brandsema, M.D.
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Associate Professor of Clinical Neurology
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Department: Neurology
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Contact information
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Division of Neurology
2b Children's Hospital of Philadelphia
2b 3501 Civic Center Blvd., 1st Floor
3a Philadelphia, PA 19104
Philadelphia, PA 19104
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2b Children's Hospital of Philadelphia
2b 3501 Civic Center Blvd., 1st Floor
3a Philadelphia, PA 19104
Philadelphia, PA 19104
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Office: 215-590-1719
32 Fax: 215-590-1771
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32 Fax: 215-590-1771
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Education:
21 7 IB c
50 Armand Hammer United World College of the American West, 1998.
21 7 BA 42 (Biochemistry and Molecular Biology/Music Double Major) c
2a Dartmouth College, 2002.
21 9 M.D. c
2d Dalhousie University, 2007.
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Permanent link21 7 IB c
50 Armand Hammer United World College of the American West, 1998.
21 7 BA 42 (Biochemistry and Molecular Biology/Music Double Major) c
2a Dartmouth College, 2002.
21 9 M.D. c
2d Dalhousie University, 2007.
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14d Anil R Wadhwani, Ashna Aggarwal, Steven Loscalzao, Megan L McSherry, Justin L Lockman, John Frederick Brandsema, Jennifer McGuire, Susan Matesanz: Pearls & Oy-sters: Severe Myotonic Crisis Resembling Malignant Hyperthermia. Neurology 104(8): e213497, Apr 2025.
205 Katlyn Elizabeth McGrattan, Robert J Graham, Alicia Hofelich Mohr, Anna Miles, Jacqui Allen, Juliet Ochura, Kayla Hernandez, Katie Walsh, Vamshi Rao, Melanie Stevens, Lindsay Alfano, Mackenzi Coker, Carmen Leon-Astudillo, Leann Schow Smith, John Brandsema, Hiba Farah, Julia Welc, Deborah Salle Levy, Miranda Clements, Whitney J Tang, Tina Duong, Carolina Tesi Rocha, Graham Schenck, Heather McGhee, Keeley Nichols, Ashley Brown, Allison Brown, Diana Castro, Basil T Darras e1 : Characterization of swallowing biomechanics and function in untreated infants with spinal muscular atrophy: A natural history dataset J Neuromuscul Dis 12(1): 22143602241308762, Jan-Feb 2025.
183 Natalie L Goedeker, Amanda Rogers, Mark Fisher, Kapil Arya, John F Brandsema, Hiba Farah, Michelle A Farrar, Marcia V Felker, Melissa Gibbons, Omer Abdul Hamid, Matthew Harmelink, Karen Herbert, Elizabeth Kichula, Kiana King, Arpita Lakhotia, Bo Hoon Lee, Nancy L Kuntz, Julie Parsons, Rebecca Rehborg, Aravindhan Veerapaniyan, Craig M Zaidman b4 : Outcomes of early-treated infants with spinal muscular atrophy: A multicenter, retrospective cohort study Muscle Nerve 70(6): 1247-1256, Dec 2024.
d8 Susan E Matesanz, Jonathan B Edelson, Katherine A Iacobellis, Erika Mejia, John F Brandsema, Carol A Wittlieb-Weber, Oluwatimilehin Okunowo, Heather Griffis, Kimberly Y Lin 89 : Subspecialty Health Care Utilization in Pediatric Patients With Muscular Dystrophy in the United States Neurol Clin Pract 2 2e 14(4): e200312, Aug 2024.
123 John F Brandsema, Matthew Ginsberg, Hideki Hoshino, Masakazu Mimaki, Satoru Nagata, Vamshi K Rao, Katherine Ruzhansky, Niraja Suresh, Emmanuelle Tiongson, Hideo Yamanouchi, Glen Frick, Eden Hicks, Serena Liao, James F Howard Jr; MG 303 Study Group 98 : Eculizumab in Adolescent Patients With Refractory Generalized Myasthenia Gravis: A Phase 3, Open-Label, Multicenter Study Pediatr Neurol 2 2f 156(1): 198-207, Jul 2024.
12d Rebecca J Willcocks, Alison M Barnard, Michael J Daniels, Sean C Forbes, William T Triplett, John F Brandsema, Erika L Finanger, William D Rooney, Sarah Kim, Dah-Jyuu Wang, Donovan J Lott, Claudia R Senesac, Glenn A Walter, H Lee Sweeney, Krista Vandenborne b0 : Clinical importance of changes in magnetic resonance biomarkers for Duchenne muscular dystrophy Ann Clin Transl Neurol 11(1): 67-78, Jan 2024.
139 Licht DJ, Brandsema JF, Jacobwitz M, von Rhein M, Ehrler M and Latal B.: Neurologic Disorders in Children with Heart Disease. Swaiman’s Pediatric Neurology (Seventh Edition). K. Swaiman et al (Eds) (eds.). Elsevier, Page: 1554-1567, 2024.
12e Brandsema JF and Darras BT: Dystrophinopathies. Rosenberg's Molecular and Genetic Basis of Neurological and Psychiatric Disease, Seventh Edition. Rosenberg and JM Pascual (eds.). London: Elsevier Academic Press, 2: 535-574, 2024.
118 Mohassel P, Yun P, Syeda S….Brandsema J...Bonnemann, CG: A comprehensive study of skeletal muscle imaging in FHL1-related reducing body myopathy. Ann Clin Transl Neurol Jul 2023 Notes: epub ahead of print.
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Selected Publications
da Jiachen Zhou, Sigrid Nilius, Olga Pilipczuk, Anna Scowcroft, Thaïs Tarancón, Frank Tennigkeit, Piotr Zaremba, Nishtha Chandra, Nancy Kuntz, Jonathan Strober, John Brandsema d2 : Treatment Patterns and Disease Burden of Juvenile Myasthenia Gravis in the United States: A Cohort Study Using Health Care Claims Databases Neurology 105(1): e213736, Jul 2025.14d Anil R Wadhwani, Ashna Aggarwal, Steven Loscalzao, Megan L McSherry, Justin L Lockman, John Frederick Brandsema, Jennifer McGuire, Susan Matesanz: Pearls & Oy-sters: Severe Myotonic Crisis Resembling Malignant Hyperthermia. Neurology 104(8): e213497, Apr 2025.
205 Katlyn Elizabeth McGrattan, Robert J Graham, Alicia Hofelich Mohr, Anna Miles, Jacqui Allen, Juliet Ochura, Kayla Hernandez, Katie Walsh, Vamshi Rao, Melanie Stevens, Lindsay Alfano, Mackenzi Coker, Carmen Leon-Astudillo, Leann Schow Smith, John Brandsema, Hiba Farah, Julia Welc, Deborah Salle Levy, Miranda Clements, Whitney J Tang, Tina Duong, Carolina Tesi Rocha, Graham Schenck, Heather McGhee, Keeley Nichols, Ashley Brown, Allison Brown, Diana Castro, Basil T Darras e1 : Characterization of swallowing biomechanics and function in untreated infants with spinal muscular atrophy: A natural history dataset J Neuromuscul Dis 12(1): 22143602241308762, Jan-Feb 2025.
183 Natalie L Goedeker, Amanda Rogers, Mark Fisher, Kapil Arya, John F Brandsema, Hiba Farah, Michelle A Farrar, Marcia V Felker, Melissa Gibbons, Omer Abdul Hamid, Matthew Harmelink, Karen Herbert, Elizabeth Kichula, Kiana King, Arpita Lakhotia, Bo Hoon Lee, Nancy L Kuntz, Julie Parsons, Rebecca Rehborg, Aravindhan Veerapaniyan, Craig M Zaidman b4 : Outcomes of early-treated infants with spinal muscular atrophy: A multicenter, retrospective cohort study Muscle Nerve 70(6): 1247-1256, Dec 2024.
d8 Susan E Matesanz, Jonathan B Edelson, Katherine A Iacobellis, Erika Mejia, John F Brandsema, Carol A Wittlieb-Weber, Oluwatimilehin Okunowo, Heather Griffis, Kimberly Y Lin 89 : Subspecialty Health Care Utilization in Pediatric Patients With Muscular Dystrophy in the United States Neurol Clin Pract 2 2e 14(4): e200312, Aug 2024.
123 John F Brandsema, Matthew Ginsberg, Hideki Hoshino, Masakazu Mimaki, Satoru Nagata, Vamshi K Rao, Katherine Ruzhansky, Niraja Suresh, Emmanuelle Tiongson, Hideo Yamanouchi, Glen Frick, Eden Hicks, Serena Liao, James F Howard Jr; MG 303 Study Group 98 : Eculizumab in Adolescent Patients With Refractory Generalized Myasthenia Gravis: A Phase 3, Open-Label, Multicenter Study Pediatr Neurol 2 2f 156(1): 198-207, Jul 2024.
12d Rebecca J Willcocks, Alison M Barnard, Michael J Daniels, Sean C Forbes, William T Triplett, John F Brandsema, Erika L Finanger, William D Rooney, Sarah Kim, Dah-Jyuu Wang, Donovan J Lott, Claudia R Senesac, Glenn A Walter, H Lee Sweeney, Krista Vandenborne b0 : Clinical importance of changes in magnetic resonance biomarkers for Duchenne muscular dystrophy Ann Clin Transl Neurol 11(1): 67-78, Jan 2024.
139 Licht DJ, Brandsema JF, Jacobwitz M, von Rhein M, Ehrler M and Latal B.: Neurologic Disorders in Children with Heart Disease. Swaiman’s Pediatric Neurology (Seventh Edition). K. Swaiman et al (Eds) (eds.). Elsevier, Page: 1554-1567, 2024.
12e Brandsema JF and Darras BT: Dystrophinopathies. Rosenberg's Molecular and Genetic Basis of Neurological and Psychiatric Disease, Seventh Edition. Rosenberg and JM Pascual (eds.). London: Elsevier Academic Press, 2: 535-574, 2024.
118 Mohassel P, Yun P, Syeda S….Brandsema J...Bonnemann, CG: A comprehensive study of skeletal muscle imaging in FHL1-related reducing body myopathy. Ann Clin Transl Neurol Jul 2023 Notes: epub ahead of print.
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