J. Cobb Scott, Ph.D.

Associate Professor of Psychiatry at the Hospital of the University of Pennsylvania
Department: Psychiatry
Contact information
Brain Behavior Laboratory
Department of Psychiatry
5th Floor, Suite 5B
3700 Hamilton Walk
University of Pennsylvania
Philadelphia, PA 19104-6085
Department of Psychiatry
5th Floor, Suite 5B
3700 Hamilton Walk
University of Pennsylvania
Philadelphia, PA 19104-6085
Office: 215-662-7388
Email:
scott1 at upenn dot edu
scott1 at upenn dot edu
Publications
Education:
B.A. (Psychology)
Wesleyan University, 1999.
M.S. (Psychology)
San Diego State University, 2006.
Ph.D. (Clinical Psychology)
University of California, San Diego, 2009.
Permanent linkB.A. (Psychology)
Wesleyan University, 1999.
M.S. (Psychology)
San Diego State University, 2006.
Ph.D. (Clinical Psychology)
University of California, San Diego, 2009.
Selected Publications
Scott JC, Lynch KG, Cenkner DP, Kehle-Forbes SM, Polusny MA, Gur RC, Chen S, Foa EB, & Oslin DW: Neurocognitive Predictors of Treatment Outcomes in Psychotherapy for Comorbid PTSD and Substance Use Disorders. Journal of Consulting and Clinical Psychology 89(11): 937-946, Nov 2021.Scott JC, Slomiak ST, Jones JD, Rosen AFG, Moore TM, Gur RC: Association of Cannabis with Cognitive Functioning in Adolescents and Young Adults: A Systematic Review and Meta-analysis. JAMA Psychiatry 75(6): 585-595, Jun 2018.
Scott JC, Rosen AFG, Moore TM, Roalf DR, Satterthwaite TD, Calkins ME, Ruparel K, Gur RE, & Gur RC: Cannabis Use in Youth is Associated with Limited Alterations in Brain Structure. Neuropsychopharmacology 44(8): 1362-1369, Jul 2019.
Abdallah CG, Wrocklage KM, Averill CL, Akiki T, Schweinsburg BC, Roy A, Martini B, Southwick SM, Krystal JH, & Scott JC: Anterior Hippocampal Dysconnectivity in Posttraumatic Stress Disorder: A Dimensional and Multimodal Approach. Translational Psychiatry 7(2): e1045, Feb 2017.
Van Pelt AE, Scott JC, Morales KH, Matshaba M, Gur RC, Tshume O, Thuto B, Lowenthal ED, Moore TM: Structural validity of a computerized neurocognitive battery for youth affected by human immunodeficiency virus in Botswana. Psychological Assessment 34(2): 139-146, Feb 2022.
Scott JC, Harb GC, Brownlow J, Greene J, Gur RC, & Ross RJ: Verbal Memory Functioning Moderates Psychotherapy Treatment Response for PTSD-Related Nightmares. Behaviour Research and Therapy 91: 24-32, Apr 2017.
Scott JC, Wolf DH, Calkins ME, Bach EC, Weidner J, Ruparel K, Moore TM, Jones JD, Jackson CT, Gur RE, & Gur RC: Cognitive Functioning in Adolescent and Young Adult Cannabis Users in the Philadelphia Neurodevelopmental Cohort. Psychology of Addictive Behaviors 31(4): 423-434, Jun 2017.
Scott JC, Matt GE, Wrocklage KM, Crnich C, Jordan J, Southwick SM, Krystal JH, Schweinsburg BC: A Quantitative Meta-Analysis of Neurocognitive Functioning in Posttraumatic Stress Disorder. Psychological Bulletin 141(1): 105-40, Jan 2015.
Wrocklage KM, Schweinsburg BC, Krystal JH, Trejo M, Roy A, Weisser V, Moore TM, Southwick SM, Scott JC: Neuropsychological Functioning in Veterans with Posttraumatic Stress Disorder: Associations with Performance Validity, Comorbidities, and Functional Outcomes. Journal of the International Neuropsychological Society 22(4): 399-411, Apr 2016.
Scott JC, Woods SP, Wrocklage KM, Schweinsburg BC, Southwick SM, Krystal JH: Prospective Memory in Posttraumatic Stress Disorder. Journal of the International Neuropsychological Society 22(7): 724-34, Aug 2016.
Scott JC, Moore TM, Stein DJ, Pretorius A, Zingela Z, Nagdee M, Ngqengelele L, King MC, McClellan JM, Port AM, Jackson C, Ruparel K, Susser ES, Gur RC: Adaptation and validation of a computerized neurocognitive battery in the Xhosa of South Africa. Neuropsychology 35(6): 581–594, Sep 2021.
Akiki TJ, Averill CL, Wrocklage KM, Scott JC, Averill LA, Schweinsburg B, Alexander-Bloch A, Martini B, Southwick SM, Krystal JH, & Abdallah CG: Default Mode Network Abnormalities in Posttraumatic Stress Disorder: A Novel Network-Restricted Topology Approach. NeuroImage 176: 489-498, Aug 2018.
Jones JD, Calkins ME, Scott JC, Bach EC, & Gur RE: Cannabis Use, Polysubstance Use, and Psychosis Spectrum Symptoms in a Community-Based Sample of US Youth. Journal of Adolescent Health 60(6): 653-659, Jun 2017.
Scott JC, Woods SP, Vigil O, Heaton RK, Schweinsburg BC, Ellis RJ, Grant I, Marcotte TD: A Neuropsychological Investigation of Multitasking in HIV Infection: Implications for Everyday Functioning. Neuropsychology 25(4): 511-9, Jul 2011.
Wen Z, Hammoud MZ, Scott JC, Jimmy J, Brown L, Marin MF, Asnaani A, Gur RC, Foa EB, Milad MR.: Impact of exogenous estradiol on task-based and resting-state neural signature during and after fear extinction in healthy women. Neuropsychopharmacology 46(13): 2278-2287, Dec 2021.
Moore TM, Butler ER, Cobb Scott J, Port AM, Ruparel K, Njokweni LJ, Gur RE, Gur RC: When CAT is not an Option: Complementary Methods of Test Abbreviation for Neurocognitive Batteries. Cognitive Neuropsychiatry 26(1): 35-54, Jan 2021.
Wrocklage KM, Averill LA, Scott JC, Averill CL, Schweinsburg BC, Trejo M, Roy A, Weisser V, Kelly C, Martini B, Harpaz-Rotem I, Southwick SM, Krystal JH, & Abdallah CG : Cortical Thickness Reduction in Combat Exposed U.S. Veterans With and Without PTSD. European Neuropsychopharmacology 27(5): 515-525, May 2017.
Moore TM, Martin IK, Gur OM, Jackson CT, Scott JC, Calkins ME, Ruparel K, Port AM, Nivar I, Krinsky HD, Gur RE, & Gur RC: Characterizing Social Environment’s Association with Neurocognition Using Census and Crime Data Linked to the Philadelphia Neurodevelopmental Cohort. Psychological Medicine 46: 599-610, Feb 2016.
Scott JC, Woods SP, Carey CL, Weber E, Bondi MW, Grant I: Neurocognitive Consequences of HIV Infection in Older Adults: An Evaluation of the "Cortical" Hypothesis. AIDS and Behavior 15(6): 1187-96, Aug 2011.
Moore TM, Scott JC, Reise SP, Port AM, Jackson CT, Ruparel K, Savitt AP, Gur RE, Gur RC: Development of an Abbreviated Form of the Penn Line Orientation Test Using Large Samples and Computerized Adaptive Test Simulation. Psychological Assessment 27(3): 955-64, Sep 2015.
Scott JC, Pietrzak RH, Southwick SM, Jordan J, Silliker N, Brandt CA, Haskell SG: Military Sexual Trauma Interacts with Combat Exposure to Increase Risk for Posttraumatic Stress Symptomatology in Female Iraq and Afghanistan Veterans. The Journal of Clinical Psychiatry 75(6): 637-43, Jun 2014.
Pietrzak RH, Scott JC, Neumeister A, Lim YY, Ames D, Ellis KA, Harrington K, Lautenschlager NT, Szoeke C, Martins RN, Masters CL, Villemagne VL, Rowe CC, Maruff P; Australian Imaging, Biomarkers and Lifestyle (AIBL) Research Group.: Anxiety Symptoms, Cerebral Amyloid Burden and Memory Decline in Healthy Older Adults Without Dementia: 3-year Prospective Cohort Study. The British Journal of Psychiatry 204: 400-1, May 2014.
Scott JC, Woods SP, Vigil O, Heaton RK, Grant I, Ellis RJ, Marcotte TD: Script Generation of Activities of Daily Living in HIV-Associated Neurocognitive Disorders. Journal of the International Neuropsychological Society 17(4): 740-5, Jul 2011.
Tsai J, Whealin JM, Scott JC, Harpaz-Rotem I, Pietrzak RH: Examining the Relation Between Combat-Related Concussion, a Novel 5-Factor Model of Posttraumatic Stress Symptoms, and Health-Related Quality of Life in Iraq and Afghanistan Veterans. The Journal of Clinical Psychiatry 73(8): 1110-8, Aug 2012.
Scott JC, Pietrzak RH, Mattocks K, Southwick SM, Brandt C, Haskell S: Gender Differences in the Correlates of Hazardous Drinking Among Iraq and Afghanistan Veterans. Drug and Alcohol Dependence 127(1-3): 15-22, Jan 2013.
Morgan EE, Woods SP, Smith C, Weber E, Scott JC, Grant I: Lower Cognitive Reserve Among Individuals with Syndromic HIV-Associated Neurocognitive Disorders (HAND). AIDS and Behavior 16(8): 2279-85, Nov 2012.
Schweinsburg BC, Scott JC, Schweinsburg AD, Jacobus J, Theilmann RJ, Frank LR, Weber E, Grant I, Woods SP: Altered Prefronto-Striato-Parietal Network Response to Mental Rotation in HIV. Journal of Neurovirology 18(1): 74-9, Feb 2012.
Iudicello JE, Woods SP, Vigil O, Scott JC, Cherner M, Heaton RK, Atkinson JH, Grant I: Longer Term Improvement in Neurocognitive Functioning and Affective Distress Among Methamphetamine Users Who Achieve Stable Abstinence. Journal of Clinical and Experimental Neuropsychology 32(7): 704-18, Aug 2010.
Morgan EE, Woods SP, Scott JC, Childers M, Beck JM, Ellis RJ, Grant I, Heaton RK: Predictive Validity of Demographically Adjusted Normative Standards for the HIV Dementia Scale. Journal of Clinical and Experimental Neuropsychology 30(1): 83-90, Jan 2008.
Scott JC, Woods SP, Matt GE, Meyer RA, Heaton RK, Atkinson JH, Grant I: Neurocognitive Effects of Methamphetamine: A Critical Review and Meta-Analysis. Neuropsychology Review 17(3): 275-97, Sep 2007.
Woods SP, Delis DC, Scott JC, Kramer JH, Holdnack JA: The California Verbal Learning Test--Second Edition: Test-Retest Reliability, Practice Effects, and Reliable Change Indices for the Standard and Alternate Forms. Archives of Clinical Neuropsychology 21(5): 413-20, Aug 2006.
Scott JC, Woods SP, Patterson KA, Morgan EE, Heaton RK, Grant I, Marcotte TD: Recency Effects in HIV-Associated Dementia are Characterized by Deficient Encoding. Neuropsychologia 44(8): 1336-43, 2006.
Neylan TC, Jasiukaitis PA, Lenoci M, Scott JC, Metzler TJ, Weiss DS, Schoenfeld FB, Marmar CR: Temporal Instability of Auditory and Visual Event-Related Potentials in Posttraumatic Stress Disorder. Biological Psychiatry 53(3): 216-25, Feb 2003.
Casaletto KB, Umlauf A, Moore DJ, Woods SP, Scott JC, Heaton RK: Abbreviated Goal Management Training Shows Preliminary Evidence as a Neurorehabilitation Tool for HIV-associated Neurocognitive Disorders among Substance Users. The Clinical Neuropsychologist 30: 107-30, Jan 2016.
Kalkstein S, Scott JC, Biester R, Brownlow JA, Harpaz-Rotem I, Gur RC: Comparison of Blast-Exposed OEF/OIF Veterans With and Without a History of TBI Symptoms on a Brief Computerized Neuropsychological Battery. Applied Neuropsychology: Adult Page: 92-97, Feb 2017.
Jones JD, Scott JC, Calkins ME, Ruparel K, Moore TM, Gur RC, & Gur RE: Correspondence Between Adolescent and Informant Reports of Substance Use: Findings from the Philadelphia Neurodevelopment Cohort. Addictive Behaviors 65: 13-18, Sep 2016.
Akiki TJ, Averill CL, Wrocklage KM, Schweinsburg BC, Scott JC, Martini B, Averill LA, Southwick SM, Krystal JH, & Abdallah CG: The Association of PTSD Symptom Severity with Localized Hippocampus and Amygdala Atrophy. Chronic Stress 1: 1-10, Feb 2017.
Gur RE, Moore TM, Rosen AFG, Barzilay R, Roalf DR, Calkins ME, Ruparel K, Scott JC, Almasy L, Satterthwaite TD, Shinohara RT, Gur RC: Burden of Environmental Adversity Affecting Psychopathology, Maturation and Brain-Behavior Parameters in Youth. JAMA Psychiatry 76(9): 966-975, May 2019.
Scott JC, Van Pelt AE, Port AM, Njokweni L, Gur RC, Moore TM, Phoi O, Tshume O, Matshaba M, Ruparel K, Chapman J, & Lowenthal ED: Study Design and Protocol for the Ntemoga Study: Development of a Computerized Neurocognitive Battery for Children and Adolescents with HIV in Botswana. BMJ Open 10(8): e041099, Aug 2020.
Xu A, Larsen B, Henn A, Baller EB, Scott JC, Sharma V, Adebimpe A, Basbaum AI, Corder G, Dworkin RH, Edwards RR, Woolf CJ, Eickhoff SB, Eickhoff CR, & Satterthwaite TD: Brain responses to noxious stimuli in patients with chronic pain: A meta analysis. JAMA Network Open 4(1): e2032236, Jan 2020.