Elizabeth McDonald, MD, PhD

faculty photo
Assistant Professor of Radiology at the Hospital of the University of Pennsylvania
Department: Radiology

Contact information
Hospital of the University of Pennsylvania
3400 Spruce Street, 1 Silverstein
Philadelphia, PA 19104
BA (Biochemistry (magna cum laude))
Harvard University, 1995.
Mayo Medical School, 2003.
PhD (Molecular Neuroscience)
Mayo Graduate School of Medicine, 2003.
Permanent link
> Perelman School of Medicine   > Faculty   > Details

Selected Publications

Cruz, L, McDonald, ES, Mick, R, Czerneicki, B: Anti-HER2 Th1 Response is Superior to Breast MRI in Response to Neoadjuvant Chemotherapy in Patients with HER2 Positive Breast Cancer. Ann Surg Oncol 24(4): 1057-1063, Apr 2017.

Derakhshan JJ, McDonald ES, Siegelman ES, Schnall MD, Wehrli FW: Characterizing and Eliminating Errors in Enhancement and Subtraction Artifacts in Dynamic Contrast-Enhanced Breast MRI: Chemical Shift Artifact of the Third Kind Magnetic Resonance in Medicine 2017 Notes: in press.

McDonald ES, McCarthy AM, Weinstein SP, Schnall MD, Conant EF: BI-RADS category 3 comparison: probably benign category after recall from screening before and after implementation of digital breast tomosynthesis. Radiology 162837, Jul 2017 Notes: doi: 10.1148/radiol.2017162837.

McDonald ES, Mankoff D, Makvandi M, Chu W, Chu Y, Mach RH, Zeng C: Sigma-2 ligands and PARP inhibitors synergistically trigger cell death cancer cells. Biochem Biophys Res Commun 486(3): 788-795, May 2017.

Conant EF, Keller BM, Pantalone L, Gastounioti A, McDonald ES, Kontos D: Agreement between breast percentage density estimations from standard-dose versus synthetic digital mammograms: Results from a large screening cohort using automated measures. Radiology Jun;283(3):673-680, 2017.

McDonald ES, Oustimov A, Weinstein SP, Synnestvedt M, Schnall MD, Conant EF: Effectiveness of digital breast tomosynthesis compared with digital mammography: Outcomes analysis from 3 years of breast cancer screening. JAMA Oncology 2(6): 737-743, Jun 2016.

Lowenfeld, L., Zaheer, S., Oechsle, C, Fracol, M., Datta, J, Xu, S, Fitzpatrick, E, Roses, RE, Fisher, CS, McDonald, ES, Zhang, PJ, DeMichele,A, Mick, R., Koski, GK, Czerniecki, BJ.: Addition of anti-estrogen therapy to anti-HER2 dendritic cell vaccination improves regional nodal immune response and pathologic complete response rate in patients with ERpos/HER2pos early breast cancer. OncoImmunology 2017.

Zuckerman SP, Maidment ADA, Weinstein SP, McDonald ES, Conant EF: Imaging With Synthesized 2D Mammography: Differences, Advantages, and Pitfalls Compared With Digital Mammography. AJR Am J Roentgenol. 209: 222-229, 2017.

Chudgar, AV, Conant, EF, Weinstein, SP, Keller, BM, Synnestvedt, M, Yamartino, P, McDonald, ES: Digital Breast Tomosynthesis versus Digital Mammography alone Screen Detected Breast Cancers: Assessment of Disease Extent on Contrast-enhanced Magnetic Resonance Imaging. Clinical Radiology S0009-9260(17): 30078-8, Mar 2017.

Zuckerman S,Conant EF,Keller B,Weinstein S,McDonald ES.: Implementation of synthesized 2D mammography in a population-based digital breast tomosynthesis screening program. Radiology 28(1): 730-736, Dec 2016 Notes: Nominated for Scientific Paper of the Year AuntMinnie.com.

McDonald ES, Mankoff DA, Mach RH: Novel strategies for breast cancer imaging: new imaging agents to guide treatment. J Nuc Med 57: 69S-74S, Feb 2016.

Pertuz S, McDonald ES, Weinstein SP, Conant EC, Kontos D: Fully-automated quantitative estimation of volumetric breast density from digital breast tomosynthesis images: Preliminary results and comparison with digital mammography and magnetic resonance imaging. Radiology 279(1): 65-74, 2016.

Lowenfeld, L, Zaheer, S, Oechsle, C, Fracol, M, Datta, J, Xu, S, Fitzpatrick, E, Roses, RE, Fisher, CS, McDonald, ES, Zhang, PJ, DeMichele, A, Mick, R, Koski, GK, Czerniecki, BJ. : Addition of Anti-Estrogen Therapy to Anti-HER2 Dendritic Cell Vaccination Improves Regional Nodal Immune Response and Pathologic Complete Response Rate in Patients with ERpos/HER2pos Early Breast Cancer. Oncoimmunology 2016 Notes: online 7/1/16.

Naha PC, Lau KC, Hsu JC, Hajfathalian M, Mian S, Chhour P, Uppuluri L, McDonald ES, Maidment AD, Cormode DP: Gold silver alloy nanoparticles (GSAN): an imaging probe for breast cancer screening with dual-energy mammography or computed tomography. Nanoscale 8(28): 13740-54, Jul 2016.

Makvandi, M, Xu, K, Lieberman, BP, Anderson, R, Effron, SS, Winters, H, Zeng, C, McDonald, ES, Pryma, DA, Greenberg, RA, Mach, RH.: A radiotracer strategy to quantify PARP-1 expression in vivo provides a biomarker that can enable patient selection for PARP inhibitor therapy. Cancer Research 76(15): 4516-24, Aug 2016.

McDonald ES, Clark A, Tchou J, Zhang, P, Freedman, G.: Clinical diagnosis and management of breast cancer. J Nuc Med 57: 9S-16S, Feb 2016 Notes: Featured on cover.

Mitsumori LM, McDonald ES, Neligan PC, Maki JH: Peripheral Magnetic Resonance Lymphangiography: Techniques and Applications. Tech Vasc Inter Radiol 19(4): 262-272, Dec 2016.

Korhonen KE, Weinstein SP, McDonald ES, Conant EF: Strategies to increase cancer detection: Review of true-positive and false-negative results at digital breast tomosynthesis screening. Radiographics 36(7): 1954-1965, Nov-Dec 2016.

McDonald ES, Hammersley JA, Chou SS, Rahbar H, Scheel JR, Lee CI, Liu CL, Lehman CD, Partridge SC.: Performance of DWI as a Rapid Unenhanced Technique for Detecting Mammographically Occult Breast Cancer in Elevated-Risk Women with Dense Breasts. AJR Am Journal of Roentgenol 207(1): 205-16, Jul 2016.

Chen L, Ray S, Keller BM, Pertuz S, McDonald ES, Conant EF, Kontos D: The Impact of acquisition dose on quantitative breast density estimation with digital mammography: Results from ACRIN PA 4006. Radiology 280(3): 693-700, Sep 2016.

McDonald ES, McCarthy AM, Akhtar A, Synnestvedt A, Schnall M, Conant EF: Baseline screening mammography: Performance of full field digital versus digital breast tomosynthesis. American Journal of Roentgenology 205(5): 1143-8, Nov 2015.

Rahbar, H, McDonald, ES, Lee, JM, Partridge, SC, Lee, CI.: How Can Advanced Imaging Be Used to Mitigate Potential Breast Cancer Overdiagnosis? Academic Radiology 23(6): 768-73, Jun 2016.

Mitsumori LM, McDonald ES, Wilson GJ, Neligan PC, Minoshima S, Maki JH: MR Lymphangiography: How I do it. J Magn Reson Imaging 42(6): 1465-77, Dec 2015.

Makvandi M, Tilahun ED, Lieberman BP, Anderson RC, Zeng C, Xu K, Hou C, McDonald ES, Pryma DA,Mach RH: The sigma-2 receptor as a therapeutic target for drug delivery in triple negative breast cancer. Biochem Biophys Res Commun (BBRC) 467(4): 1070-1075. Nov 2015.

McDonald ES, Schopp JG, Peacock S, DeMartini WB, Rahbar H, Lehman CD, Partridge SC: Diffusion-weighted MRI: association between patient characteristics and apparent diffusion coefficients of normal breast fibroglandular tissue at 3 T. AJR Am J Roentgenol 202(5): W496-502, May 2014.

Clark AS, McDonald E, Lynch MC, Mankoff D: Using nuclear medicine imaging in clinical practice: update on PET to guide treatment of patients with metastatic breast cancer. Oncology 28(5): 424-30, May 2014.

Doot RK, McDonald ES, Mankoff DA: Role of PET quantitation in the monitoring of cancer response to treatment: review of approaches and human clinical trials. Clin Transl Imaging 2(4): 295-303, Aug 2014.

Mirzabeigi MN, McDonald ES, Chu MW, Fischer JP, Basta M, Kovach S, Wu LC, Serletti J, Kanchwala S: Operative management of locoregional cancer recurrence following post-mastectomy breast reconstruction-indications and outcomes. American Society for Reconstructive Microsurgery 2016 Notes: Oral Presentation.

Partridge SC, McDonald ES: Diffusion weighted magnetic resonance imaging of the breast: protocol optimization, interpretation, and clinical applications. Magn Reson Imaging Clin N Am 21(3): 601-624, Aug 2013 Notes: doi: 10.1016/j.mric.2013.04.007.

back to top
Last updated: 09/15/2017
The Trustees of the University of Pennsylvania