Sarah E. Hopkins, MD, MSPH

Associate Professor of Clinical Neurology
Co-Director, Penn/CHOP Agespan MS/Neuroinflammatory Disorders Fellowship
Section Head, Multiple Sclerosis and Neuroinflammatory Disorders, Division of Neurology
Children's Hospital of Philadelphia
Department: Neurology
Contact information
Children's Hospital of Philadelphia
Division of Neurology
Colket Building, 3501 Civic Center Blvd.
Philadelphia, PA 19104
Division of Neurology
Colket Building, 3501 Civic Center Blvd.
Philadelphia, PA 19104
Office: 215-590-1719
Fax: 215-590-1771
Fax: 215-590-1771
Education:
B.S. (Biology, minor in Secondary Education)
Ursinus College, Collegeville, PA, 1996.
M.S.P.H. (Epidemiology)
Rollins School of Public Health, Emory University, Atlanta, GA, 1997.
M.D. (Medicine)
University of Arkansas for Medical Sciences College of Medicine, Little Rock, AR, 2004.
Permanent linkB.S. (Biology, minor in Secondary Education)
Ursinus College, Collegeville, PA, 1996.
M.S.P.H. (Epidemiology)
Rollins School of Public Health, Emory University, Atlanta, GA, 1997.
M.D. (Medicine)
University of Arkansas for Medical Sciences College of Medicine, Little Rock, AR, 2004.
Selected Publications
Marefi A, Grasso EA, Canna SW, Behrens EM, Shekdar K, Narula S, Hopkins S, Banwell BL.: Clinical Reasoning: A 9-Year-Old Girl With CNS Immune Dysregulation. Neurology 105: e213999, Sep 2025.Espinoza DA, Zrzavy T, Breville G, Thebault S, Marefi A, Mexhitaj I, Yamashita LD, Kan M, Bacchus M, Legaspi J, Fernandez S, Melamed A, Stubblebine M, Kim Y, Martinez Z, Diorio C, Schulte-Mecklenbeck A, Wiendl H, Rezk A, Li R, Narula S, Waldman AT, Hopkins SE, Banwell B, Bar-Or A.: Pediatric cerebrospinal fluid immune profiling distinguishes pediatric-onset multiple sclerosis from other pediatric-onset acute neurological disorders. bioRxiv May 2025.
Roalf D, Atkins A, Czernuszenko A, Pecsok MK, McDonald-McGinn DM, Schmitt JE, Roeske MJ, Hopkins S, Freedman P, Alexander-Bloch A, Schabdach J, Jung B, Crowley TB, Gallagher RS, McGinn DE, Moberg PJ, Ruparel K, Shinohara RT, Turetsky BI, White L, Zackai EH, Gur RC, Gur RE.: Presence, Severity, and Functional Associations of Incomplete Hippocampal Inversion in 22q11.2 Deletion Syndrome. Biol Psychiatry Cogn Neurosci Neuroimaging Apr 2025.
Mirchi A and Hopkins S: Pediatric acquired demyelinating syndromes: updates in diagnosis, testing, and management. Current Opinion in Pediatrics 36(6): 644-652, December 2024.
Diorio C, Hernandez-Miyares L, Espinoza DA, Banwell BL, Bar-Or A, DiNofia AM, Barz Leahy A, Martinez Z, Myers RM, Hopkins SE, Rheingold SR, Teachey DT, Viaene AN, Wray LM, Maude SL, Grupp SA, McGuire JL.: Quadriparesis and paraparesis following chimeric antigen receptor T-cell therapy in children and adolescents. Blood 144: 1387-1398, Sep 2024.
Shakin S, Altman M, Hart J, Hopkins S, Lazerow P, Caceres JA: Wall-Eyed Bilateral Internuclear Ophthalmoplegia as Part of the Clinical Presentation of Pediatric Multiple Sclerosis, Successfully Treated With Therapeutic Plasma Exchange. Pediatr Neurol 158: 124-127, Sept 2024.
Diorio C, Hernandez-Miyares L, Espinoza DA, Banwell B, Bar-Or A, DiNofia A, Barz Leahy A, Martinez Z, Myers RM, Hopkins S, Rheingold SR, Teachey DT, Viaene A, Wray L, Maude SL, Grupp SA, McGuire J.: Quadriparesis and paraparesis following chimeric antigen receptor T-cell (CART) therapy in children and adolescents. Blood June 2024 Notes: Online ahead of print.
Sarah Frankl, Angela Viaene, Arastoo Vossough, Amy Waldman, Sarah Hopkins, Brenda Banwell: Solitary Tumefactive Demyelinating Lesions in Children: Clinical and Magnetic Resonance Imaging Features, Pathologic Characteristics, and Outcomes. Pediatr Neurol 141: 141-150, May 2024.
Kornbluh A, Hopkins S: Acute Disseminated Encephalomyelitis. Reference Module in Neuroscience and Biobehavioral Psychology 2024.
Caceres JA, Saucier L, Murphy OC, Gordon-Lipkin EM, Santoro JD, Van Haren K, Pardo CA, Hopkins S: Brain Magnetic Resonance Imaging Abnormalities in Acute Flaccid Myelitis. Pediatric Neurology 149: 58-62, December 2023.