Giulia Pavani, PhD
Research Assistant Professor of Pathology and Laboratory Medicine
Department: Pathology and Laboratory Medicine
Contact information
Children's Hospital of Philadelphia
3501 Civic Center Blvd.
Colket Building, Rm. 10050
Philadelphia, PA 19104
3501 Civic Center Blvd.
Colket Building, Rm. 10050
Philadelphia, PA 19104
Office: 2674261222
Email:
PAVANIG@chop.edu
PAVANIG@chop.edu
Publications
Education:
BA (Cell and Molecular Biology)
University of Ferrara, Ferrara, Italy, 2008.
BS (Molecular and Cellular Biotechnologies)
University Vita-Salute S.Raffaele, Milan, Italy, 2010.
PhD (Molecular Biology and Biotechnology)
University of Ferrara, Ferrara, Italy, 2014.
Permanent linkBA (Cell and Molecular Biology)
University of Ferrara, Ferrara, Italy, 2008.
BS (Molecular and Cellular Biotechnologies)
University Vita-Salute S.Raffaele, Milan, Italy, 2010.
PhD (Molecular Biology and Biotechnology)
University of Ferrara, Ferrara, Italy, 2014.
Selected Publications
Pavani G, Klein JG, Nations CC, Sussman JH, Tan K, An HH, Abdulmalik O, Thom CS, Gearhart PA, Willett CM, Maguire JA, Chou ST, French DL, Gadue P.: Modeling primitive and definitive erythropoiesis with induced pluripotent stem cells. Blood Adv Jan 2024.Cheng X, Barakat R, Pavani G, Usha MK, Calderon R, Snella E, Gorden A, Zhang Y, Gadue P, French DL, Dorman KS, Fidanza A, Campbell CA, Espin-Palazon R.: Nod1-dependent NF-kB activation initiates hematopoietic stem cell specification in response to small Rho GTPases. Nat Commun 14: 7668, Nov 2023.
Wilken MB, Fonar G, Nations C, Pavani G, Tsao V, Garifallou J, Tober J, Bennett L, Maguire JA, Gagne A, Okoli N, Gadue P, Chou ST, Speck NA, French DL, Thom CS.: Tropomyosin 1 deficiency facilitates cell state transitions to enhance hemogenic endothelial cell specification during hematopoiesis. bioRxiv Sep 2023.
Breda L, Papp TE, Triebwasser MP, Yadegari A, Fedorky MT, Tanaka N, Abdulmalik O, Pavani G, Wang Y, Grupp SA, Chou ST, Ni H, Mui BL, Tam YK, Weissman D, Rivella S, Parhiz H.: In vivo hematopoietic stem cell modification by mRNA delivery. Science 381: 436-443, Jul 2023.
An HH, Gagne AL, Maguire JA, Pavani G, Abdulmalik O, Gadue P, French DL, Westhoff CM, Chou ST.: The use of pluripotent stem cells to generate diagnostic tools for transfusion medicine. Blood 140: 1723-1734, Oct 2022.
Pavani G, Klein JG, French DL, Gadue P.: Genome Engineering Human ESCs or iPSCs with Cytosine and Adenine Base Editors. Methods Mol Biol 2520: 321-333, May 2022.
Nations CC, Pavani G, French DL, Gadue P.: Modeling genetic platelet disorders with human pluripotent stem cells: mega-progress but wanting more on our plate(let). Curr Opin Hematol 28: 308-314, Sep 2021.
Borst S, Nations CC, Klein JG, Pavani G, Maguire JA, Camire RM, Drazer MW, Godley LA, French DL, Poncz M, Gadue P.: Study of inherited thrombocytopenia resulting from mutations in ETV6 or RUNX1 using a human pluripotent stem cell model. Stem Cell Reports 16: 1458-1467, Jun 2021.
Pavani G, Amendola M.: Corrigendum: Targeted Gene Delivery: Where to Land. Front Genome Ed 3: 682171, May 2021.
Pavani G, Fabiano A, Laurent M, Amor F, Cantelli E, Chalumeau A, Maule G, Tachtsidi A, Concordet JP, Cereseto A, Mavilio F, Ferrari G, Miccio A, Amendola M.: Correction of β-thalassemia by CRISPR/Cas9 editing of the α-globin locus in human hematopoietic stem cells. Blood Adv 5: 1137-1153, Mar 2021.