Scott Alan Peslak, MD, PhD
Assistant Professor of Medicine (Hematology-Oncology)
Department: Medicine
Contact information
University of Pennsylvania, Department of Medicine, Division of Hematology/Oncology
Biomedical Research Building II/III, Room 809
421 Curie Blvd
Philadelphia, PA 19104
Biomedical Research Building II/III, Room 809
421 Curie Blvd
Philadelphia, PA 19104
Education:
BS (Biochemistry, Philosophy)
University of Scranton , 2006.
PhD (Pathology)
University of Rochester School of Medicine, 2012.
MD (Medicine )
University of Rochester School of Medicine, 2014.
Permanent linkBS (Biochemistry, Philosophy)
University of Scranton , 2006.
PhD (Pathology)
University of Rochester School of Medicine, 2012.
MD (Medicine )
University of Rochester School of Medicine, 2014.
Selected Publications
Peslak, S.A., Akins, A.B., Foxwell, A.M., Iannelli, M., Grande, C., Breen, D., Russell, J.E., Uritsky, T.J., Sayani, F.A.: A novel, effective, and efficient strategy for treating sickle cell vaso-occlusive events in the infusion center setting. Blood Adv 7(3): 410-413, Feb 2023.Peslak, S.A.*, Demirci, S.*, Chandra, V., Ryu, B., Bhardwaj, S.K., Jiang, J., Rupon, J.W., Throm, R.E., Uchida, N., Leonard, A., Essawi, K., Bonifacino, A.C., Krouse, A.E., Linde, N.S., Donahue, R.E., Ferrera, F., Wielgosz, M., Abdulmalik, O., Hamagami, N., Germino-Watnick, P., Le, A., Chu, R., Hinds, M., Weiss, M.J., Tong, W., Tisdale, J.F., Blobel, G.A. : Forced enhancer-promoter rewiring to alter gene expression in animal models. Mol Ther Nucleic Acids 32: 452-465, Jan 2023.
Wakabayashi, A., Kihiu, M., Sharma, M., Thrasher, J., Saari, M., Quesnel-Vallieres M., Abdulmalik, O., Peslak, S.A., Khandros, E., Keller, C.A., Giardine, B.M., Hardison, R.C., Shi, J., Blobel, G.A. : Identification and characterization of RBM12 as a novel regulator of fetal hemoglobin expression Blood Adv 6(23): 5956-5968, Dec 2022.
Peslak S.A., Khandros E., Huang P., Wakabayashi A., Abbas T., Abdulmalik O., Keller C.A., Hardison R.C., Shi J., Blobel G.A. : Regulation of Fetal Hemoglobin Production in Adult Erythroid Cells by Protein Phosphatase 6C (PPP6C). American Society of Hematology Annual Meeting. Atlanta, GA. Dec 2022 Notes: "Poster Presentation"
Adema, V., Ma, F, Kanagal-Shamanna, R., Thongon, N., Montalban-Bravo, G., Yang, H., Peslak, S.A. Wang, F., Acha, P., Sole, F., Lockyer, P., Cassari, M., Maciejewski, J.P., Visconte, V., Ganan-Gomez, I., Song, Y., Bueso-Ramos, C., Pellegrini, M., Tuyet, M.T., Bejar, R., Carew, J.S., Halene, S., Santini, V., Al-Atrash, G., Clise-Dwyer, K., Garcia-Manero, G., Blobel, G.A., Colla, S. : Targeting the EIF2AK1 signaling pathway rescues red blood cell production in SF3B1-mutant myelodysplastic syndromes with ringed sideroblasts. Blood Cancer Discov 3(6): 554-567, Nov 2022.
Peslak S.A., Khandros E., Huang P., Wakabayashi A., Abbas T., Abdulmalik O., Keller C.A., Hardison R.C., Shi J., Blobel G.A.: Protein phosphatase 6C (PPP6C) loss raises fetal hemoglobin levels and reduces cell sickling. Red Cell Club Meeting (virtual), New Haven, CT. Oct 2022 Notes: "Poster Presentation"
Peslak S.A., Khandros E., Huang P., Wakabayashi A., Abbas T., Abdulmalik O., Keller C.A., Hardison R.C., Shi J., Blobel G.A..: Protein phosphatase 6C (PPP6C) loss raises fetal hemoglobin levels and reduces cell sickling. Doris Duke Charitable Foundation Clinician Scientist Meeting, New York, NY. Oct 2022 Notes: "Poster Presentation"
Huang, P., Peslak, S.A., Lan, X., Khandros, E., Yano, J.A., Sharma, M., Keller, C.A., Giardine, B., Qin, K., Abdulmalik, O., Hardison, R.C., Shi, J., Blobel, G.A. : HIC2 controls developmental hemoglobin switching by repressing BCL11A transcription Nat Genet 54(9): 1417-1426, Sep 2022.
Qin, K., Huang, P., Feng, R., Keller, C.A., Peslak, S.A., Khandros, E., Saari, M., Lan, X., Mayuranathan, T., Doerfler, P.A., Abdulmalik, O., Giardine, B., Chou, S.T., Shi, J., Hardison, R.C., Weiss, M.J., Blobel, G.A. : Dual function NFI factors control fetal hemoglobin silencing in adult erythroid cells. Nat Genet 54(6): 874-884, Jun 2022.
Peslak S.A., Khandros E., Huang P., Kihiu M., Abdulmalik O., Keller C.A., Hardison R.C., Shi J., Blobel G.: Protein phosphatase 6C (PPP6C) loss raises fetal hemoglobin levels and reduces cell sickling. Hemoglobin Switching Conference, Crete, Greece. May 2022 Notes: "Poster Presentation"