George L Anesi, MD, MSCE, MBE

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Assistant Professor of Medicine (Pulmonary, Allergy and Critical Care) at the Hospital of the University of Pennsylvania
Director, Medical Critical Care Bioresponse Program and Special Treatment Unit, Hospital of the University of Pennsylvania, Hospital of the University of Pennsylvania
Attending Physician, Hospital of the University of Pennsylvania
Attending Physician, Penn Medicine E-lert eICU, Penn Medicine E-lert eICU
Core Faculty, PAIR (Palliative and Advanced Illness Research) Center, University of Pennsylvania Perelman School of Medicine
Faculty Fellow, Center for Clinical Epidemiology and Biostatistics (CCEB), University of Pennsylvania Perelman School of Medicine
Instructor of Medicine, Division of Pulmonary, Allergy, and Critical Care, Department of Medicine, University of Pennsylvania Perelman School of Medicine
Senior Fellow, Center for Public Health Initiatives (CPHI), University of Pennsylvania
Senior Fellow, Leonard Davis Institute of Health Economics (LDI), University of Pennsylvania
Department: Medicine

Contact information
3400 Spruce Street, 5037 Gates Building
Philadelphia, PA 19104
Office: 215-908-4563
Education:
BS (Chemistry and Biological Chemistry)
University of Chicago, 2006.
MD (Medicine)
Case Western Reserve University, 2011.
MA (Bioethics)
Case Western Reserve University, 2011.
MS (Clinical Epidemiology)
University of Pennsylvania Perelman School of Medicine, 2017.
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Description of Clinical Expertise

Critical care; sepsis; acute respiratory failure; shock; multi-system organ failure; influenza and respiratory viral infections; COVID-19; global health

Description of Other Expertise

hospital operations; preparedness and response; hospital capacity strain

Description of Research Expertise

My research interests focus on the evaluation of critical care and acute care resources during times of strain to the system, including situations of dynamic strain (i.e., random variation in demand, seasonal trends, epidemics, and disasters) and fixed strain (i.e., critical illness in resource-limited settings domestically and globally).

Selected Publications

Anesi GL, Xiong R, Delgado MK: Frequency and trends of pre-pandemic surge periods in U.S. emergency departments, 2006-2019. Society of Critical Care Medicine (SCCM) Critical Care Congress, Phoenix, AZ. Crit Care Med. 52(1): S29, Jan 2024.

Agarwal A, Anesi GL: Non-conventional ventilators during the COVID-19 pandemic: clinical efficacy, crisis research considerations, and preparedness next steps. Crit Care Med 2024 Notes: In Press.

Sathe NA, Bhatraju PK, Morrell ED, Stanaway IB, Anesi GL, Andrews A, Bai H, Brett-Major DM, Broadhurst MJ, Campbell ES, Gonzalez M, Homami S, Hypes CD, Irwin A, Kratochvil CJ, Krolikowski K, Kumar VK, Lee RA, Liebler JM, Marts LT, Mosier JM, Mukherjee V, Postelnicu R, Rodina V, Spainhour C, Srivastava A, Wyles D, Lutrick K, Landsittel DP, Cobb JP, Uyeki TM, Segal LN, Sevransky JE, Evans L, Wurfel MM, for the Severe Acute Respiratory Infection – Preparedness (SARI-PREP) Study Group: Severe Acute Respiratory Infection – Preparedness (SARI-PREP): Proteomic approaches for predicting need for prolonged respiratory support in acute hypoxemic respiratory failure. American Public Health Association (APHA) Annual Meeting, Atlanta, GA Nov 2023.

Lutrick K, Baccam N, Tang N, Rivers P, Anesi GL, Bhatraju PK, Brett-Major DM, Cobb JP, Kratochvil CJ, Kumar VK, Mukherjee V, Postelnicu R, Segal LN, Sevransky JE, Wurfel MM, Wyles D, Evans L, for the Severe Acute Respiratory Infection – Preparedness (SARI-PREP) Study Group: Racial/Ethnic Differences in COVID-19 Symptoms, Length of Stay, and Outcomes in a National Cohort of Critically Ill Patients. American Public Health Association (APHA) Annual Meeting, Atlanta, GA Nov 2023.

Evans L, Cobb JP, Anesi GL, Bhatraju PK, Brett-Major DM, Kratochvil CJ, Kumar VK, Lutrick K, Mukherjee V, Postelnicu R, Segal LN, Sevransky JE, Wurfel MM, Wyles D, for the Severe Acute Respiratory Infection – Preparedness (SARI-PREP) Study Group: Clinical Investigation During Public Health Emergencies Requires an Innovative Consortium Approach. American Public Health Association (APHA) Annual Meeting, Atlanta, GA Nov 2023.

Anesi GL, Savarimuthu SM, Invernizzi J, Hyman R, Ramkillawan A, Eddey C, Wise RD, Smith MTD: Critical care resiliency during COVID-19-related capacity strain in a resource-limited setting: Report from South Africa. Critical Care Society of Southern Africa (CCSSA) Critical Care Congress, Gqeberha, South Africa October 2023.

Chesley CF, Chowdhury M, Small D, Schaubel D, Liu VX, Lane-Fall MB, Halpern SD, Anesi GL: Disparities in Hospital Length of Stay Among Severely Ill Patients With Community Acquired Sepsis and Acute Respiratory Failure Across 27 Hospitals. American Thoracic Society (ATS) International Conference, Washington, DC. Am J Respir Crit Care Med. 207: A2775, May 2023.

Biser J, Sevransky JE, Cobb JP, Anesi GL, Andrews A, Bhatraju PK, Evans LE, Kumar VK, Adeboyejo R: Building multi-sector partnerships to improve clinical surveillance and research in public health emergencies. National Association of County and City Health Officials (NACCHO) Preparedness Summit, Atlanta, GA April 2023.

Anesi GL, Savarimuthu SM, Invernizzi J, Smith M, Hyman R, Ramkillawan A, Eddey C, Wise RD: Pandemic Epidemiology of COVID-19 and Non-COVID-19 Critical Illness in a Resource-Limited Setting. Society of Critical Care Medicine (SCCM) Critical Care Congress, San Francisco, CA. Crit Care Med. 51(1): 104, Jan 2023.

Kohn R, Harhay MO, Weissman GE, Urbanowicz R, Wang W, Anesi GL, Scott S, Bayes B, Greysen R, Halpern SD, Kerlin MP: A Data-Driven Analysis of Ward Capacity Strain Metrics That Predict Clinical Outcomes Among Survivors of Acute Respiratory Failure. J Med Syst 47(1), 2023.

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Last updated: 04/11/2024
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