George L Anesi, MD, MSCE, MBE
Assistant Professor of Medicine (Pulmonary, Allergy and Critical Care) at the Hospital of the University of Pennsylvania
Director, Medical Critical Care Bioresponse Program and Special Treatment Unit, Hospital of the University of Pennsylvania, Hospital of the University of Pennsylvania
Attending Physician, Hospital of the University of Pennsylvania
Attending Physician, Penn Medicine E-lert eICU, Penn Medicine E-lert eICU
Core Faculty, PAIR (Palliative and Advanced Illness Research) Center, University of Pennsylvania Perelman School of Medicine
Faculty Fellow, Center for Clinical Epidemiology and Biostatistics (CCEB), University of Pennsylvania Perelman School of Medicine
Instructor of Medicine, Division of Pulmonary, Allergy, and Critical Care, Department of Medicine, University of Pennsylvania Perelman School of Medicine
Senior Fellow, Center for Public Health Initiatives (CPHI), University of Pennsylvania
Senior Fellow, Leonard Davis Institute of Health Economics (LDI), University of Pennsylvania
Department: Medicine
Contact information
3400 Spruce Street, 5037 Gates Building
Philadelphia, PA 19104
Philadelphia, PA 19104
Office: 215-908-4563
Publications
Education:
BS (Chemistry and Biological Chemistry)
University of Chicago, 2006.
MA (Bioethics)
Case Western Reserve University, 2011.
MD (Medicine)
Case Western Reserve University, 2011.
MS (Clinical Epidemiology)
University of Pennsylvania Perelman School of Medicine, 2017.
Permanent linkBS (Chemistry and Biological Chemistry)
University of Chicago, 2006.
MA (Bioethics)
Case Western Reserve University, 2011.
MD (Medicine)
Case Western Reserve University, 2011.
MS (Clinical Epidemiology)
University of Pennsylvania Perelman School of Medicine, 2017.
Description of Clinical Expertise
Critical care; sepsis; acute respiratory failure; shock; multi-system organ failure; influenza and respiratory viral infections; COVID-19; global healthDescription of Other Expertise
hospital operations; preparedness and response; hospital capacity strainDescription of Research Expertise
My research interests focus on the evaluation of critical care and acute care resources during times of strain to the system, including situations of dynamic strain (i.e., random variation in demand, seasonal trends, epidemics, and disasters) and fixed strain (i.e., critical illness in resource-limited settings domestically and globally).Selected Publications
Chesley CF, Chowdhury M, Small D, Schaubel D, Liu VX, Lane-Fall MB, Halpern SD, Anesi GL: Disparities in Hospital Length of Stay Among Severely Ill Patients With Community Acquired Sepsis and Acute Respiratory Failure Across 27 Hospitals. American Thoracic Society (ATS) International Conference, Washington, DC May 2023.Biser J, Sevransky JE, Cobb JP, Anesi GL, Andrews A, Bhatraju PK, Evans LE, Kumar VK, Adeboyejo R: Building multi-sector partnerships to improve clinical surveillance and research in public health emergencies. National Association of County and City Health Officials (NACCHO) Preparedness Summit, Atlanta, GA April 2023.
Anesi GL, Savarimuthu SM, Invernizzi J, Smith M, Hyman R, Ramkillawan A, Eddey C, Wise RD: Pandemic Epidemiology of COVID-19 and Non-COVID-19 Critical Illness in a Resource-Limited Setting. Society of Critical Care Medicine (SCCM) Critical Care Congress, San Francisco, CA. Crit Care Med. 51(1): 104, Jan 2023.
Kohn R, Harhay MO, Weissman GE, Urbanowicz R, Wang W, Anesi GL, Scott S, Bayes B, Greysen R, Halpern SD, Kerlin MP: A Data-Driven Analysis of Ward Capacity Strain Metrics That Predict Clinical Outcomes Among Survivors of Acute Respiratory Failure. J Med Syst 47(1), 2023.
Anesi GL, Savarimuthu SM, Invernizzi J, Hyman R, Ramkillawan A, Eddey C, Wise RD, Smith MTD: ICU Mortality Across Prepandemic and Pandemic Cohorts in a Resource-Limited Setting: A Critical Care Resiliency Analysis From South Africa. Chest Critical Care 1(1), 2023 Notes: https://www.sciencedirect.com/science/article/pii/S2949788423000059.
Chesley CF, Chowdhury M, Small D, Schaubel D, Liu VX, Lane-Fall MB, Halpern SD, Anesi GL: Racial Disparities in Length of Stay Among Severely Ill Patients Presenting With Sepsis and Acute Respiratory Failure. JAMA Netw Open 6(5): e239739, 2023.
Ginestra JC, Kohn R, Hubbard RA, Auriemma CL, Patel MS, Anesi GL, Kerlin MP, Weissman GE: Association of Time of Day with Delays in Antimicrobial Initiation among Ward Patients with Hospital-onset Sepsis. Ann Am Thorac Soc 20(9): 1299-1308, 2023.
Kohn R, Weissman GE, Wang W, Ingraham NE, Scott S, Bayes B, Anesi GL, Halpern SD, Kipnis P, Liu VX, Dudley RA, Kerlin MP: Prediction of In-hospital Mortality Among Intensive Care Unit Patients Using Modified Daily Laboratory-based Acute Physiology Score, Version 2. Med Care 61(8): 562-569, 2023.
Bhatraju PK, Morrell ED, Stanaway IB, Sathe NA, Srivastava A, Postelnicu R, Andrews A, Gonzalez M, Kratochvil CJ, Kumar VK, Anesi GL, Wyles D, Broadhurst MJ, Brett-Major D, Mukherjee V, Sevransky JE, Landsittel D, Gharib SA, Uyeki TM, Cobb JP, Liebler JM, Crosslin DR, Jarvik GP, Segal LN, Evans L, Mikacenic C, Wurfel MM: Angiopoietin-Like4 Is a Novel Marker of COVID-19 Severity. Crit Care Explor 5(1): e0827, 2023.
Anesi GL: Awake-Prone Positioning in COVID-19: New Data on Efficacy, Timing, and Mechanism. Crit Care Med 51(9): 1270-1272, 2023.