Paul N. Fiorilli, MD
Assistant Professor of Clinical Medicine (Cardiovascular Medicine)
Program Director, Interventional Cardiology Fellowship, Hospital of the University of Pennsylvania, Perelman School of Medicine
Co-Director, TAVR Program, Hospital of the University of Pennsylvania
Director, Structural Heart Disease, Hospital of the University of Pennsylvania
Department: Medicine
Contact information
11th Floor South Perelman
34th Civic Center Blvd.
Philadelphia, PA 19104
34th Civic Center Blvd.
Philadelphia, PA 19104
Office: 215-662-2181
Fax: 215-615-3073
Fax: 215-615-3073
Education
B.S. (B.S. Honors in Biology and English)
Georgetown University, 2006.
M.D (Doctor of Medicine)
Georgetown University School of Medicine, 2010.
Permanent linkB.S. (B.S. Honors in Biology and English)
Georgetown University, 2006.
M.D (Doctor of Medicine)
Georgetown University School of Medicine, 2010.
Selected Publications
Safdar NZ, Khedro T, Khan SA, Khan AH, Goldberg D, Fiorilli PN, Goldberg S.: Lifetime management of aortic stenosis: A primer for the generalist. Am J Med October 2026.Schurr JW, Shah T, Ezema A, Bertot J, Rai A, Fiorilli P, Tsao A, Fanaroff A, Giri J, Nathan A.: Bayesian Meta-Analysis of Transcatheter Mitral Valve Edge-to-Edge Repair for Secondary Mitral Regurgitation in Heart Failure. JACC Adv August 2026.
Bhasin V, Vakilpour A, Ravindra K, Koropeckyj-Cox D, Denduluri S, Fiorilli P, Parikh A, Hu R, Scherrer-Crosbie M.: Utilization of Guideline-Directed Medical Therapies and Transcatheter-Edge-to-Edge Repair in Patients with Significant Secondary Mitral Regurgitation. Cardiology Jun 2026.
Pliakos EE, Acker AM, Fiorilli PN, Tsao AL, Lawrence KM, Desai ND, Rogers T, Khan JM, Giri JS, Nathan AS.: Cost-Effectiveness of Valve-in-Valve Transcatheter Aortic Valve Replacement Versus Redo-Surgical Aortic Valve Replacement for Degenerated Bioprosthetic Aortic Valve. J Soc Cardiovasc Angiogr Interv 5: 105400, May 2026.
Toubat O, Pitoulis F, Szeto J, Catalano M, Shin M, Iyengar A, Fiorilli PN, Jolley MA, Acker MA, Szeto WY, Ibrahim ME.: Outcomes following the first 100 cases of a new robotic mitral valve program. JTCVS Open 32: 101813, Apr 2026.
Litt M, Enriquez A, Fiorilli P, Schaller R, See VY.: Intracardiac echocardiography-guided implantation of an active-fixation ventricular leadless pacemaker through a transcatheter tricuspid valve replacement. HeartRhythm Case Rep 12: 893-896, Apr 2026.
Pliakos EE, Reddy K, Atluri P, Herrmann HC, Fiorilli P, Alkhouli M, Baron SJ, Giri J, Nathan AS.: Cost-Effectiveness of Valve-in-Valve Transcatheter Mitral Valve Replacement Versus Redo Surgical Mitral Valve Replacement for Degenerated Bioprosthetic Mitral Valve. Struct Heart 10: 100808, Feb 2026.
Ibrahim ME, Toubat O, Sperry AE, Bonnell L, Elenbaas C, Anzai I, Fiorilli PN, Bonow RO, Smith RL, Habib RH, Acker MA, Szeto WY.: Outcomes of re-repair versus replacement after failed primary mitral regurgitation repair: STS Adult Cardiac Surgery Database analysis. Ann Thorac Surg(25), 01173-7, Nov 2025 Notes: https://doi.org/10.1016/j.athoracsur.2025.11.017.
Shah T, Yang L, Shah Y, Eberly L, Khatana SAM, Kumbhani DJ, Elmariah S, Alkhouli M, Baron SJ, Desai ND, Szeto WY, Lawrence K, Fanaroff AC, Fiorilli PN, Tsao AL, Groeneveld PW, Giri J, Nathan A.: Effect of Transcatheter Aortic Valve Replacement Program Ratings on Case Selection. JACC Cardiovasc Interv 18(22): 2777-2786, Nov 2025.
Tedla BA, Kim YY, Kobayashi T, Fiorilli PN, Giri JS, Burke M, Partington SL, Abraham BP, Vaiyani D, Vaikunth SS.: Pulmonary Embolism, Thrombectomy, and Catheter-Directed Lysis in Pregnant Woman With Fontan Palliation. JACC Case Rep 30(16): 103959, Jun 2025 Notes: https://doi.org/10.1016/j.jaccas.2025.103959.