Susan E McClory, MD, PhD

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Assistant Professor of Pediatrics (Oncology) at the Children's Hospital of Philadelphia
Attending Physician, Division of Oncology, Children's Hospital of Philadelphia
Instructor A of Pediatric Oncology, University of Pennsylvania
Department: Pediatrics

Contact information
Children's Hospital of Philadelphia
Division of Oncology
4010 Colket Translational Research Building
3501 Civic Center Blvd
Philadelphia, PA 19104
Office: 267-303-4638
Education:
B.S. (Molecular Genetics)
Ohio State University, 2005.
PhD (Integrated Biomedical Sciences)
Ohio State University, 2012.
MD (Medicine)
Ohio State University , 2014.
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Selected Publications

McClory SE, Maude SL.: The Current State of Chimeric Antigen Receptor T Cell Therapy for B Lymphoblastic Leukemia. Hematol Oncol Clin North Am Jul 2023.

McClory SE, Bardhan O, Rome KS, Giles JR, Baxter AE, Xu L, Gimotty PA, Faryabi RB, Wherry EJ, Pear WS, Jordan MS.: The pseudokinase Trib1 regulates the transition of exhausted T cells to a KLR(+) CD8(+) effector state, and its deletion improves checkpoint blockade. Cell Rep 42: 112905, Jul 2023.

Susan E. McClory, Oishi Bardhan, Kelly S. Rome, Lanwei Xu, Phyllis A. Gimotty, Martha S. Jordan, and Warren S. Pear: Trib1 Inhibition Promotes the KLR Effector State and Augments Checkpoint Blockade to Enhance T Cell Function during T Cell Exhaustion. American Society of Hematology Annual Meeting, Virtual 2022 Notes: Poster.

Susan McClory, MD, PhD; Oishi Bardhan; Kelly Rome, PhD; Warren Pear, MD, PhD; and Martha Jordan, PhD: Trib1 Inhibits Viral-specific T Cell Responses during Chronic Infection by Promoting Terminal Exhaustion. Keystone Symposium on Advances in Checkpoints Immunology from Autoimmunity to Oncology to Infectious Diseases, Virtual 2022 Notes: Poster.

Rome, K. S., Stein, S. J., Kurachi, M., Petrovic, J., Schwartz, G. W., Mack, E. A., Uljon, S., Wu, W. W., DeHart, A. G., McClory, S. E., Xu, L., Gimotty, P. A., Blacklow, S. C., Faryabi, R. B., Wherry, E. J., Jordan, M. S., Pear, W. S.: Trib1 regulates T cell differentiation during chronic infection by restraining the effector program. J Exp Med 217(5): e20190888, May 2020.

McClory, S, and Teachey, D.T.: It’s Not a No Brainer: Improved Outcome in Children with Philadelphia Chromosome Positive B-ALL When Treated with a TKI with Better CNS Penetration. Hematologist 17(6): 358-366, 2020.

McClory, S., Cahen V.C., Li Y., Duke J.L., Monos D., Ramos M., Bunin N., Getz K.D., Seif A.E.: Celiac disease risk determined by HLA-DQ genotype protects against GVHD in a dose-responsive manner. American Society of Transplant and Cellular Therapy, Virtual 2020 Notes: Poster.

Victor, A. R., Nalin, A. P., Dong, W., McClory, S., Wei, M., Mao, C., Kladney, R. D., Youssef, Y., Chan, W. K., Briercheck, E. L., Hughes, T., Scoville, S. D., Pitarresi, J. R., Chen, C., Manz, S., Wu, L. C., Zhang, J., Ostrowski, M. C., Freud, A. G., Leone, G. W., Caligiuri, M. A., Yu, J.: IL-18 Drives ILC3 Proliferation and Promotes IL-22 Production via NF-kappaB. J Immunol 199(7): 2333-2342, Oct 2017.

Scoville, S. D., Mundy-Bosse, B. L., Zhang, M. H., Chen, L., Zhang, X., Keller, K. A., Hughes, T., Chen, L., Cheng, S., Bergin, S. M., Mao, H. C., McClory, S., Yu, J., Carson, W. E., 3rd, Caligiuri, M. A., Freud, A. G.: A Progenitor Cell Expressing Transcription Factor RORgammat Generates All Human Innate Lymphoid Cell Subsets. Immunity 44(5): 1140-50, May 2016.

Martin del Campo, S. E., Levine, K. M., Mundy-Bosse, B. L., Grignol, V. P., Fairchild, E. T., Campbell, A. R., Trikha, P., Mace, T. A., Paul, B. K., Jaime-Ramirez, A. C., Markowitz, J., Kondadasula, S. V., Guenterberg, K. D., McClory, S., Karpa, V. I., Pan, X., Olencki, T. E., Monk, J. P., Mortazavi, A., Tridandapani, S., Lesinski, G. B., Byrd, J. C., Caligiuri, M. A., Shah, M. H., Carson, W. E., 3rd: The Raf Kinase Inhibitor Sorafenib Inhibits JAK-STAT Signal Transduction in Human Immune Cells. J Immunol 195(5): 1995-2005, Sep 2015.

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Last updated: 01/15/2024
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