Carlyn Patterson Gentile, MD, PhD
Assistant Professor of Neurology at the Children's Hospital of Philadelphia
Center for Injury Prevention and Recovery Senior Fellow, Children's Hospital of Philadelphia and the University of Pennsylvania
Director, Headache Fellowship, Children's Hospital of Philadelphia
Department: Neurology
Graduate Group Affiliations
Publications
Links
Search PubMed for articles
For a list of my peer-reviewed publications please see the following link.
Search PubMed for articles
For a list of my peer-reviewed publications please see the following link.
Education:
BA (Neuroscience)
Hamilton College, 2006.
PhD (Neuroscience)
Albert Einstein College of Medicine, 2012.
MD (Medicine)
Albert Einstein College of Medicine, 2014.
Permanent linkBA (Neuroscience)
Hamilton College, 2006.
PhD (Neuroscience)
Albert Einstein College of Medicine, 2012.
MD (Medicine)
Albert Einstein College of Medicine, 2014.
Description of Clinical Expertise
I have clinical expertise in child neurology and headache. I see a range of primary and secondary headache disorders with a particular focus on post-traumatic headache. I am certified in peripheral nerve block procedures for the acute treatment of headache, and onobotulinum toxin A chemodenervation for the treatment of chronic headache.Description of Research Expertise
I have research expertise in the following areas:1. Visual neuroscience including encoding of visual information in neural networks, modeling of neural networks, and visual signal processing using perceptual and electrophysiologic metrics.
2. Application of model-based fitting to analysis of symptom clusters in youth with headache.
3. Biomarker clinical research, particularly related to concussion and headache in pediatric populations.
4. Use of biosensors to continuously monitor real-world light exposure.
5. Computer software programing using Matlab coding language.
Selected Publications
Patterson Gentile, C., Aguirre, G.K., Ciuffreda,K.J., Joshi, N.R., Arbogast, K.B., Master, C.L.: Model based fitting of pattern reversal visually evoked potentials provides a reliable characterization of waveform components. Biomedical Signal Processing and Control 99: 106863, January 2025.Szperka, C.L., Witzman, S., Ostapenko, S., Farrar, J.T., Hsu, J.Y., Malavolta, C.P., Bunney, J.D., Bange, E.M., Patterson Gentile, C., Velasquez, G., Marquez de Prado, B., Cosico, M., Lee, M., Pojomovsky McDonnell,P., Prelack, M.S., Chadehumbe, M.A., Stephenson, D.J., Kichula, E.A., Tomaine, S.C., Hershey, A.D.: Patient headache questionnaires can improve headache diagnosis and treatment in children. Headache: Journal of Head and Face Pain 63(10): 1359-1371, December 2024.
Patterson Gentile, C. Szperka C.L., Hershey, A.D.: Cluster Analysis of Migraine-Associated Symptoms (CAMS) in Youth: A retrospective cross-sectional multicenter study. Headache: Journal of Face and Head Pain October 2024 Notes: online ahead of print.
Patterson Gentile, C., Hershey A.D., Szperka, C.L: A critical appraisal of the International Classification of Headache Disorders Migraine Diagnostic Criteria based on a retrospective multicenter cross-sectional headache registry study in youth. Headache: Journal of Face and Head Pain October 2024 Notes: doi: 10.1111/head.14858. Online ahead of print.
Szperka, C.L., Evans, M., Patterson Gentile, C., Panigrahi, P., Raj, N., Marquez de Prado, B., Andrew D. Hershey, A.D., Gelfand, A.A.: Headache Trajectories in Children and Adolescents with New Onset Continuous Headache Cephalalgia 44(10), October 2024.
Patterson Gentile C, Rosenthal S, Blume H, Rastogi RG, McVige J, Bicknese A, Ladak A, Zaveri H, Greene K, Barlow K.: American Headache Society white paper on treatment of post‐traumatic headache from concussion in youth. Headache: Journal of Head and Face Pain 67(9): doi: 10.1111/head.14795, October 2024.
Patterson Gentile, C, Spitschan, M, Taskin, HO, Bock, AS, Aguirre, GK: Temporal sensitivity for achromatic and chromatic flicker across the visual cortex. Journal of Neuroscience 44(21): e1395232024, May 2024.
Chong, C.D., Ashina, S., Kamins, J., Scher, A., Patterson Gentile, C., Finkel, A., Oshinsky, M., Schwedt, T.J.: NINDS common data elements for post-traumatic headache. A project from the American Headache Society post-traumatic headache special interest section. Headache: Journal of Face and Head Pain 64(1): 1-2, January 2024.
Huber, C.M., Patton, D.A., Round, K.R., Patterson Gentile, C., Master, C.L., Arbogast, K.B.: Neurophysiological effects of repeated soccer heading in youth. ASME Journal of Biomedical Engineering 145, September 2023.
Patterson Gentile, C., Aguirre, G.K., Hershey, A.D. and Szperka, C.L.: Symptoms associated with headache in youth. Cephalalgia 43(7): 03331024231187162, July 2023.