Jennifer Pogoriler, M.D., Ph.D.
Associate Professor of Pathology and Laboratory Medicine at the Children's Hospital of Philadelphia
Department: Pathology and Laboratory Medicine
Contact information
The Children's Hospital of Philadelphia
Department of Pathology and Laboratory Medicine
3401 Civic Center Boulevard
5th Floor Main Building Suite 5NW14
Philadelphia, PA 19104
Department of Pathology and Laboratory Medicine
3401 Civic Center Boulevard
5th Floor Main Building Suite 5NW14
Philadelphia, PA 19104
Fax: 215-590-1736
Lab: 215-590-1735
Lab: 215-590-1735
Email:
pogorilerj@chop.edu
pogorilerj@chop.edu
Education:
BA (Biology)
Williams College, 1999.
PhD (Cancer Biology)
University of Chicago, 2006.
MD (Medicine)
University of Chicago, 2008.
Permanent linkBA (Biology)
Williams College, 1999.
PhD (Cancer Biology)
University of Chicago, 2006.
MD (Medicine)
University of Chicago, 2008.
Selected Publications
Guerra AD, Matkar S, Acholla C, Casey C, Li G, Mazzeschi M, Patel K, Krytska K, Chen C, Balyasny S, Kalna J, Kamitsuka P, Gerelus M, Polkosnik G, Groff D, Mukherje A, Adams C, Witek G, Hamilton AK, Martinez D, Pogoriler J, Spear TT, Li Y, Jung P, Alvarado D, Lauriola M, Maris JM, Wolpaw AJ, Bosse KR, Dimitrov D, Mir M, Jelev DV, Mossé YP: A humanized anaplastic lymphoma kinase (ALK)-directed antibody-drug conjugate with pyrrolobenzodiazepine payload demonstrates efficacy in ALK-expressing cancers. Nat Commun 16(11), aug 2025.Sun NY, Kumar S, Kim YS, Varghese D, Mendoza A, Nguyen R, Okada R, Reilly K, Widemann B, Pommier Y, Elloumi F, Dhall A, Taniyama D, Patel M, Aber E, Contreras CF, Kaplan RN, Kiseljak-Vassiliades K, Wierman ME, Martinez D, Pogoriler J, Hamilton AK, Diskin SJ, Maris JM, Robey RW, Gottesman MM, Del Rivero J, Roper N. : Identification of the Notch ligand DLK1 as an immunotherapeutic target and regulator of tumor cell plasticity and chemoresistance in adrenocortical carcinoma. Nat Commun 16(1), Jul 2025.
Nelson, ND and Pogoriler, J: Congenital Cystic Lung Lesions: An Update on Clinical and Pathologic Correlates. Surgical Pathology Clinics June 2025.
Younes S, Suarez CJ, Pogoriler J, Bhatti T, Shenoy A, Saab R, Surrey LF, Tan SY.: Congenital Peribronchial Myofibroblastic Tumors Harbor a Recurrent EGFR Kinase Domain Duplication. Modern Pathology 38: 100661, Feb 2025.
Lindsay J. Nitsche, Colleen E. Bontrager, Paul J. Devlin, Lea F. Surrey, Jennifer E. Pogoriler, Portia A. Kreiger, Theodore W. Laetsch, Frank Balis, Alexander S. Fairman, Peter Mattei, Stephanie M. Fuller: Complex Pediatric Neoplasms: The Role of Congenital Cardiothoracic Surgery. JTCVS Techniques Feb 2025.
Pogoriler J, Vargas SO: Cystic masses of the pediatric lung: update on congenital pulmonary airway malformation and its differential diagnosis. Virchows Arch 486: 177-188, Jan 2025.
Steffin D, Ghatwai N, Montalbano A, Rathi P, Courtney AN, Arnett AB, Fleurence J, Sweidan R, Wang T, Zhang H, Masand P, Maris JM, Martinez D, Pogoriler J, Varadarajan N, Thakkar SG, Lyon D, Lapteva N, Zhuyong M, Patel K, Lopez-Terrada D, Ramos CA, Lulla P, Armaghany T, Grilley BJ, Gottschalk S, Dotti G, Metelitsa LS, Heslop HE, Brenner MK, Sumazin P, Heczey A: Interleukin-15-armoured GPC3 CAR T cells for patients with solid cancers. Nature 637: 940-946, jan 2025.
Mossé YP, Polkosnik G, Pogoriler J, Mattei P, States LJ, Maris JM.: Anaplastic Lymphoma Kinase Inhibition Therapy for Hereditary Neuroblastoma. JCO Precis Oncol 2025.
Karen I. Ramirez-Suarez, MD • Santiago Martinez-Correa, MD • Luis O. Tierradentro-Garcia, MD • Ammie M. White, MD • Mariangeles Medina Perez, MD Hansel J. Otero, MD • David M. Biko, MD • Lisa R. Young, MD • Jennifer Pogoriler, MD, PhD • John P. Lichtenberger, MD • Jordan B. Rapp, MD: Pediatric Diffuse Lung Disease in Infants: Imaging Findings and Histopathologic Correlation. RadioGraphics 44(11): e240022, Nov 2024.
Hamilton AK, Radaoui AB, Tsang M, Martinez D, Conkrite KL, Patel K, Sidoli S, Delaidelli A, Modi A, Rokita JL, Lane MV, Hartnett N, Lopez RD, Zhang B, Zhong C, Ennis B, Miller DP, Brown MA, Rathi KS, Raman P, Pogoriler J, Bhatti T, Pawel B, Glisovic-Aplenc T, Teicher B, Erickson SW, Earley EJ, Bosse KR, Sorensen PH, Krytska K, Mosse YP, Havenith KE, Zammarchi F, van Berkel PH, Smith MA, Garcia BA, Maris JM, Diskin SJ: A proteogenomic surfaceome study identifies DLK1 as an immunotherapeutic target in neuroblastoma. Cancer Cell 42(11): 1970-1982, Nov 2024.