Rebecca A Hubbard, Ph.D.

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Professor of Biostatistics in Biostatistics and Epidemiology at the Hospital of the University of Pennsylvania
Department: Biostatistics and Epidemiology

Contact information
Department of Biostatistics, Epidemiology & Informatics
University of Pennsylvania School of Medicine
604 Blockley Hall
423 Guardian Drive
Philadelphia, PA 19104
Office: 215-898-3311
Fax: 215-573-4865
B.S. (Ecology & Evolution, summa cum laude)
University of Pittsburgh, Pittsburgh, PA, 1999.
M.Sc. (Epidemiology)
University of Edinburgh, Edinburgh, UK, 2001.
M.Sc. (Applied Statistics, with honors)
Oxford University, Oxford, UK, 2002.
Ph.D. (Biostatistics)
University of Washington, Seattle, WA , 2007.
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Description of Research Expertise

Dr. Hubbard's research focuses on development and application of statistical methodology for studies using observational data from community medical practice. This work encompasses evaluation of screening and diagnostic test performance, methods for comparative effectiveness studies, and health services research. A wealth of data on healthcare utilization, performance, and outcomes are available from electronic medical records. However, the complex observation scheme giving rise to these data necessitates careful study design and analysis to ensure that inference is valid. Dr. Hubbard’s methodological research emphasizes development of statistical tools for such inference and has been applied to studies of cancer screening, aging and dementia, pharmacoepidemiology, women’s health, and behavioral health.

Selected Publications

Sobrin L, Yu Y, Han S, Susarla G, Kempen JH, Hubbard RA, VanderBeek BL: Angiotensin converting enzyme-inhibitors and incidence of non-infectious uveitis in a large healthcare claims database. Ophthalmic Epidemiology In press, 2021.

Huang W, Schinasi LH, Kenyon C, Moore K, Melly S, Hubbard RA, Zhao Y, Diez Roux AV, Forrest CB, Maltenfort M, J De Roos AJ: Effects of ambient air pollution on childhood asthma exacerbation in the Philadelphia metropolitan region, 2011 – 2014. Environmental Research In press, 2021.

Mamtani R, Lund J, Hubbard RA: Considering the totality of evidence: Combining real-world data with clinical trial results to better inform decision-making. Pharmacoepidemiology & Drug Safety In press, 2021.

Ellis DE, Hubbard RA, Willis AW, Zuppa AF, Zaoutis TE, Hennessy S: Comparative neurological safety of fluoroquinolones vs. therapeutic alternatives. Pharmacoepidemiology & Drug Safety In press, 2021.

Harrigan J, Hubbard RA, Thomas S, Riello RJ, Bange E, Mamtani M, Mamtani R: Association between US administration endorsement of hydroxychloroquine for COVID-19 and outpatient prescribing. Journal of General Internal Medicine 35: 2826-2828, September 2020.

Upshaw JN, Hubbard RA, Hu J, Brown J, Schmitz K, Ky B: Physical activity during and after breast cancer therapy and associations of baseline physical activity with changes in cardiac function by echocardiography. Cancer Medicine 9(17): 6122-6131, September 2020.

Mahmud N, Hubbard RA, Kaplan DE, Serper M: Declining cirrhosis hospitalizations in the wake of the COVID-19 pandemic: A national cohort study. Gastroenterology 159(3): 1134-1136, September 2020.

Hubbard RA, Tong J, Duan R, Chen Y: Reducing bias due to outcome misclassification for epidemiologic studies using EHR-derived probabilistic phenotypes. Epidemiology 31(4): 542-550, July 2020.

Tom SE, Phadke M, Crane PL, Hubbard RA, Stern Y, Larson EB: Association of demographic and early-life socioeconomic factors by firth cohort with dementia incidence among US adults born between 1893 and 1949. JAMA Network Ope 3(7): e2011094, July 2020.

Demissei BG, Adusumalli S, Hubbard RA, Denduluri S, Narayan V, Clark AS, Shah P, Knollman H, Getz KD, Aplenc R, Carver JR, Ky B: Cardiologist involvement in breast cancer patients treated with trastuzumab. JACC: CardioOncology 2(2): 179-189, June 2020.

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Last updated: 04/18/2021
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