Dennis Jgamadze, MSc, MD, PhD

faculty photo
Research Assistant Professor of Neurosurgery
Research Associate, Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania
Department: Neurosurgery

Contact information
3450 Hamilton Walk
Room 176A, Stemmler Hall
Philadelphia, PA 19104
Education:
MD (Medicine)
David Tvildiani Medical University, 2007.
MSc (Molecular Bioengineering)
Dresden University of Technology, 2009.
PhD (Biology)
Dresden University of Technology, 2014.
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Selected Publications

Jgamadze D, Lim JT, Zhang Z, Harary PM, Germi J, Mensah-Brown K, Adam CD, Mirzakhalili E, Singh S, Gu JB, Blue R, Dedhia M, Fu M, Jacob F, Qian X, Gagnon K, Sergison M, Fruchet O, Rahaman I, Wang H, Xu F, Xiao R, Contreras D, Wolf JA, Song H, Ming GL, Chen HI.: Structural and functional integration of human forebrain organoids with the injured adult rat visual system. Cell Stem Cell 30(2): 137-152.e7, Feb 2023.

Jgamadze D, Johnson VE, Wolf JA, Cullen DK, Song H, Ming GL, Smith DH, Chen HI.: Modeling traumatic brain injury with human brain organoids. Curr Opin Biomed Eng 14: 52-58, Jun 2020.

Cullen DK, Gordián-Vélez WJ, Struzyna LA, Jgamadze D, Lim J, Wofford KL, Browne KD, Chen HI.: Bundled Three-Dimensional Human Axon Tracts Derived from Brain Organoids. iScience 21: 57-67, Nov 2019.

Chen HI, Jgamadze D, Lim J, Mensah-Brown K, Wolf JA, Mills JA, Smith DH.: Functional Cortical Axon Tracts Generated from Human Stem Cell-Derived Neurons. Tissue Eng Part A 25(9-10): 736-745, May 2019.

Liaudanskaya V, Jgamadze D, Berk AN, Bischoff DJ, Gu BJ, Hawks-Mayer H, Whalen MJ, Chen HI, Kaplan DL.: Engineering advanced neural tissue constructs to mitigate acute cerebral inflammation after brain transplantation in rats. Biomaterials 192: 510-522, Feb 2019.

Chen HI, Jgamadze D, Serruya MD, Cullen DK, Wolf JA, Smith DH.: Neural Substrate Expansion for the Restoration of Brain Function. Front Syst Neurosci 10: 1, Jan 2016 Notes: doi: 10.3389/fnsys.2016.00001.

Jgamadze D, Liu L, Vogler S, Chu LY, Pautot S.: Thermoswitching microgel carriers improve neuronal cell growth and cell release for cell transplantation. Tissue Eng Part C Methods 21(1): 65-76, Jan 2015.

Jgamadze D, Bergen J, Stone D, Jang JH, Schaffer DV, Isacoff EY, Pautot S.: Colloids as mobile substrates for the implantation and integration of differentiated neurons into the mammalian brain. PLoS One 7(1): e30293, Jan 2012.

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Last updated: 04/06/2023
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