Matthew Ziegler, MD, MSCE
Assistant Professor of Medicine (Infectious Diseases) at the Hospital of the University of Pennsylvania
Attending Physician, Hospital of the University of Pennsylvania
Attending Physician, Penn Presbyterian Medical Center
Faculty-Fellow, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania
Senior Scholar, Center for Clinical Epidemiology and Biostatics
Associate Healthcare Epidemiologist, Hospital of the University of Pennsylvania
Department: Medicine
Contact information
3 Silverstein Pavilion, 3400 Spruce Street
Philadelphia, PA 19104
Philadelphia, PA 19104
Email:
mattz@pennmedicine.upenn.edu
mattz@pennmedicine.upenn.edu
Publications
Education:
BA (Biology)
Saint Louis University, 2008.
MD
University of Wisconsin School of Medicine, 2012.
MS (Clinical Epidemiology)
University of Pennsylvania, 2018.
Permanent linkBA (Biology)
Saint Louis University, 2008.
MD
University of Wisconsin School of Medicine, 2012.
MS (Clinical Epidemiology)
University of Pennsylvania, 2018.
Description of Clinical Expertise
Infectious diseases in patients with hematologic malignancy.Description of Research Expertise
Healthcare-associated infections in patients with hematologic malignancy.Transmission of multi-drug resistant organisms within the hospital environment.
Selected Publications
Ziegler, M. J., Loughrey, S., Bekele, S., Huang, E., Tolomeo, P., David, M. Z., Lautenbach, E., Glaser, L. J., Kelly, B. J.: Comparative performance of sponge versus flocked swabs for culture-based and metagenomic detection of microbial contamination in the healthcare environment. Infect Control Hosp Epidemiol 46(8): 1-6, 2025.Baker, A. W., La Hoz, R. M., Anesi, J. A., Kwon, J. H., Wasylyshyn, A. I., Ford, E. S., Harrington, S. M., Miller, M. B., Weber, D. J., Sickbert-Bennett, E. E., Talbot, T. R., Nguyen, M. H., Kramer, K. H., Nickel, K. B., Ziegler, M. J., Arocha, D., Henderson, C., Lokhnygina, Y., Maged, A., Haridy, S., Alexander, B. D., Stout, J. E., Anderson, D. J.: Epidemiology of Healthcare Facility-Associated Nontuberculous Mycobacteria From 2012 Through 2020 in a 10-Hospital Network in the United States. Clin Infect Dis 13(8129393), 2025.
Branch-Elliman, W., Chambers, D. A., Albin, O., Batshon, L., Castejon-Ramirez, S., Cheng, V. C., Emetuche, N., Datta, R., Kamboj, M., Krein, S. L., Staub, M., Dassum, S. R., Rittmann, B., Huang, F. S., Sreeramoju, P., Stroever, S., Suleyman, G., Ting, J. Y., Witt, L. S., Ziegler, M. J., Kwon, J. H.: The life cycle of infection prevention and antimicrobial stewardship projects and interventions: the dynamic interplay of implementation and de-implementation science (Part I of II). Infect Control Hosp Epidemiol 10: 1-12, 2025.
Branch-Elliman, W., Reyes Dassum, S., Stroever, S., Albin, O., Batshon, L., Castejon-Ramirez, S., Cheng, V. C., Emetuche, N., Datta, R., Kamboj, M., Krein, S. L., Staub, M., Rittmann, B., Scaggs Huang, F., Sreeramoju, P., Suleyman, G., Ting, J. Y., Witt, L. S., Ziegler, M. J., Kwon, J. H.: Leveraging de-implementation science to promote infection prevention and stewardship: a roadmap and practical examples (Part II of II). Infect Control Hosp Epidemiol 10: 1-11, 2025.
Ziegler, M. J., Anesi, J., Tolomeo, P., Glaser, L., Cowden, L., Cressman, L., Huang, E., Patel, A., Lautenbach, E., Pegues, D. A., Kelly, B. J.: Screening and targeted prophylaxis for Clostridioides difficile infection. Clin Microbiol Infect 13(25): 00395-7, 2025.
Kwon JH, Advani SD, Branch-Elliman W, Braun BI, Cheng VC, Chiotos K, Douglas P, Gohil SK, Keller SC, Klein EY, Krein SL, Lofgren ET, Merrill K, Moehring RW, Monsees E, Perri L, Scaggs Huang F, Shelly MA, Skelton F, Spivak ES, Sreeramoju PV, Suda KJ, Ting JY, Weston GD, Yassin MH, Ziegler MJ, Mody L. : A call to action: the SHEA research agenda to combat healthcare-associated infections. Infect Control Hosp Epidemiol 45(9): 1-18, Oct 2024.
Wang X, Arya SV, Patel S, Saw S, Decena MA, Hirsh R, Pegues DA, Ziegler MJ. : Antibiotic practice and stewardship in the management of neutropenic fever: a survey of US institutions. Infect Control Hosp Epidemiol. 45(10): 1-8, Aug 2024.
Ziegler MJ, Bekele S, Loughrey S, Huang E, Tolomeo P, Kelly BJ: Post-antibiotic risk for recurrent lower respiratory tract infection during prolonged hospitalization. ECCMID Conference 2024.
Kwon, J. H., Advani, S. D., Branch-Elliman, W., Braun, B. I., Cheng, V. C., Chiotos, K., Douglas, P., Gohil, S. K., Keller, S. C., Klein, E. Y., Krein, S. L., Lofgren, E. T., Merrill, K., Moehring, R. W., Monsees, E., Perri, L., Scaggs Huang, F., Shelly, M. A., Skelton, F., Spivak, E. S., Sreeramoju, P. V., Suda, K. J., Ting, J. Y., Weston, G. D., Yassin, M. H., Ziegler, M. J., Mody, L.: A call to action: the SHEA research agenda to combat healthcare-associated infections. Infect Control Hosp Epidemiol 45(9): 1-18, 2024.
Wang, X., Arya, S. V., Patel, S., Saw, S., Decena, M. A., Hirsh, R., Pegues, D. A., Ziegler, M. J.: Antibiotic practice and stewardship in the management of neutropenic fever: a survey of US institutions. Infect Control Hosp Epidemiol 45(10): 1-8, 2024.