Mary DeAgostino-Kelly, MD, MPH

faculty photo
Assistant Professor of Clinical Obstetrics and Gynecology
Attending Physician, Gynecology, Penn Presbyterian Medical Center, Philadelphia, PA
Attending Physician, Obstetrics and Gynecology, Hospital of the University of Pennsylvania, Philadelphia, PA
Residency Program Director, Hospital of the University of Pennsylvania
Department: Obstetrics and Gynecology

Contact information
Department of Ob/Gyn
3400 Spruce St
Dulles 5
Philadelphia, PA 19104
Office: 215-662-6035
Education:
BS (Biological Sciences, Anthropology)
University of Notre Dame, 2009.
MD, MPH
Vanderbilt University School of Medicine, 2015.
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Description of Clinical Expertise

Quality Improvement, Minimally Invasive Gynecologic Surgery

Description of Research Expertise

Resident Surgical Education, Trainee Education in Quality Improvement

Selected Publications

Apple A, Jang M, Wu J, DeAgostino-Kelly M: Impact of the EMIGS curriculum on surgical skills and experience of OB-GYN residents. Annual Simulation Research Reception at Penn Medicine Feb 2026.

Ramey-Collier K, Mulugeta-Gordon L, Sonalkar S, Salva C, James A, DeAgostino-Kelly M: Resident implementation of a health disparity index to address inequities in gynecologic outcomes. CREOG/APGO Annual Meeting Feb 2026.

Hoffecker G, Wittner V, Mulugeta-Gordon L, Gysler S, DeAgostino-Kelly M, Tuteja S: Patient and provider perceptions of pharmacogenetic testing in gynecologic surgery: a cross-sectional analysis. Pharmacogenomics 13, Jan 2026.

DeAgostino-Kelly M, Combs CA, Hamm RF: Teaching Quality Improvement initiatives in Obstetrics and Gynecology. Obstetrics and Gynecology Clinics of North America Oct 2025.

Hoffecker G, Mulugeta-Gordon L, Wittner V, Wang X, Gysler S, DeAgostino-Kelly M, Tuteja S: Feasibility of pharmacogenetic-guided selection of postoperative analgesics in gynecologic surgery patients: a prospective, randomized, pilot study. Pharmacogenetics and Genomics 35(6), Aug 2025.

Broni EK, Levine LD, Sonalkar SR, Deagostino-Kelly M, Howell EA, James A: Building a pipeline: findings from Penn Ob/Gyn undergraduate summer research program. CREOG/APGO Annual Meeting Feb 2025.

Ramey-Collier K, DeAgostino-Kelly M: The Long Call. Podcast 2025.

Andriani L, Aggarwal A, Bailey N, Seltzer E, Oliver S, Mills L, DeAgostino-Kelly M, Haggerty A, Latif N: Together care: transforming perioperative care for patients undergoing benign and oncologic gynecologic surgery. NEJM Catalyst 5(12), Dec 2024.

Apple AN, Mulugeta-Gordon L, Deagostino-Kelly M, Kinson MS, Farrow MR Koelper NC, Sonalkar S, James A: High-volume surgeons and reducing racial disparities in route of hysterectomy. Journal of Minimally Invasive Gynecology 31(11), Nov 2024.

Hoffecker G, Keatb K, Mulugeta-Gordon L, Rismand M, Vermae SS, DeAgostino-Kelly M, Tuteja S: Estimated clinical utility of multi-gene pharmacogenetic testing in a retrospective cohort of gynecology patients. Pharmacogenomics 25, Nov 2024.

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Last updated: 02/17/2026
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