Sara Handley, MD, MSCE

faculty photo
Assistant Professor of Pediatrics (Neonatology & Newborn Services) at the Children's Hospital of Philadelphia
Attending Physician, Division of Neonatology, Children's Hospital of Philadelphia
Senior Fellow, Leonard Davis Institute of Health Economics, University of Pennsylvania
Department: Pediatrics

Contact information
Children's Hospital of Philadelphia
Division of Neonatology
2nd Floor Main Building
34th and Civic Center Blvd.
Philadelphia, PA 19104
Office: 267-455-5280
Education:
BA (Chemistry)
St. Olaf College, 2007.
MD
University of Minnesota Medical School, 2012.
MSCE (Clinical Epidemiology)
University of Pennsylvania, 2019.
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Description of Research Expertise

Sara Handley, MD, MSCE, is a neonatologist and health services researcher focused on evaluating the impact of the perinatal health care system, including institutional structure, organizational culture, and unit processes on perinatal outcomes and outcome variation. Perinatal health system factors in her research include perinatal regionalization (e.g., access to hospital-based childbirth care, levels of care, risk-appropriate care delivery, rural-urban differences), organizational culture (e.g., dyad-centered culture, resuscitation team culture), and neonatal care processes (i.e. moderate and preterm infant care, resuscitation). She conducts her work in collaboration with experts in biostatistics, obstetrics, organizational psychology, and health care management.

Selected Publications

Nienaber T, Muthig GP, Dysart K, Knake LA, Miller E, Handley SC, Burris HH, Culhane JF, Kim JH: Objective trends in necrotizing enterocolitis (NEC) and probiotic use utilizing Epic's Cosmos dataset. Pediatric Academic Societies Annual Meeting, Boston, MA - Poster April 2026.

Knake LA, Miller E, Handley SC, Burris HH, Nienaber T, Greenspan J, Bell EF, Dysart K: Validating a <25 weeks Gestational Age Neonatal Cohort using the Epic Cosmos Database: Continued Increased Active Treatment and Improved Survival in 21- and 22-week Infants. Epic XGM Conference, Verona, WI - Platform April 2026.

Knake LA, Miller E, Handley SC, Burris HH, Nienaber T, Greenspan J, Bell EF, Dysart K: Validating a <25 weeks Gestational Age Neonatal Cohort using the Epic Cosmos Database: Continued Increased Active Treatment and Improved Survival in 21- and 22-week Infants. Pediatric Academic Societies Annual Meeting, Boston, MA - Poster April 2026.

Handley SC, Corson CL, Radack J, Rogers EE, Sankar MN, Rosenstein MG, Lorch SA, Nembhard IM: The Culture of Dyad-Centered Care in Birth Hospitals: Differences between Neonatal and Obstetric Staff. Pediatric Academic Societies Annual Meeting, Boston, MA - Poster April 2026.

Mari KE, Huber M, Dysart K, Wilpers A, Burris HH, Handley SC: Severe Maternal Morbidity Among Births in U.S. Freestanding Children’s Hospital Delivery Units in the PHIS Database. Pediatric Academic Societies Annual Meeting, Boston, MA - Poster April 2026.

Goldstein Novick NP, Radack J, Lorch SA, Nelin TD, Salazar EG, Handley SC: Heterogeneous patients, services, and risk-adjusted outcomes by neonatal intensive care unit (NICU) acuity across the gestational age and birth weight spectrum. Pediatric Academic Societies Annual Meeting, Boston, MA - Poster April 2026.

Busse CE, Dysart K, Medoro AK, Burris HH, Handley SC: Patterns of syphilis diagnosis and treatment among maternal-infant dyads in a national sample, 2018-2024. Pediatric Academic Societies Annual Meeting, Boston, MA - Poster April 2026.

Corson CL, Nembhard IM, Radack J, Handley SC: Empathy Between Neonatal and Obstetric Team Members and Relationships with Culture and Staff-Reported Outcomes. Pediatric Academic Societies Annual Meeting, Boston, MA - Poster April 2026.

Nelin TD, Handley SC, Scott KA, Culhane JF, Greenspan J, Burris HH, Dysart K: Leveraging machine learning for prediction of grade 3 bronchopulmonary dysplasia (BPD) or death in preterm infants using Epic Cosmos data. Pediatric Academic Societies Annual Meeting, Boston, MA - Poster April 2026.

Scott KA, Culhane JF, Greenspan J, Handley SC, Knake LA, McKenney KM, Nelin TD, Son M, Dysart K, Burris HH: Trends in medically indicated and spontaneous preterm birth in the US, 2018 - 2024. Pediatric Academic Societies Annual Meeting, Boston, MA - Platform April 2026.

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Last updated: 02/12/2026
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