Laura Breda, PhD

faculty photo
Research Assistant Professor of Pediatrics
Department: Pediatrics

Contact information
Children’s Hospital of Philadelphia
3615 Civic Center Blvd, room 302B
Abramson Research Center
Philadelphia, PA 19104
Office: 2155902016
Education:
BSc
University of Ferrara, 2000.
PhD
University of Ferrara, 2004.
MS
Weill Cornell Medical College, 2012.
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Selected Publications

Deng Wulan, Rupon Jeremy W, Krivega Ivan, Breda Laura, Motta Irene, Jahn Kristen S, Reik Andreas, Gregory Philip D, Rivella Stefano, Dean Ann, Blobel Gerd A: Reactivation of developmentally silenced globin genes by forced chromatin looping. Cell 158(4): 849-860, Aug 2014.

Martin Leenus, Grigoryan Arsen, Wang Ding, Wang Jinhua, Breda Laura, Rivella Stefano, Cardozo Timothy, Gardner Lawrence B: Identification and characterization of small molecules that inhibit nonsense-mediated RNA decay and suppress nonsense p53 mutations. Cancer research 74(11): 3104-13, Jun 2014.

Breda Laura, Rivella Stefano, Zuccato Cristina, Gambari Roberto: Combining gene therapy and fetal hemoglobin induction for treatment of β-thalassemia. Expert review of hematology 6(3): 255-64, Jun 2013.

Dong A, Rivella S, Breda L: Gene therapy for hemoglobinopathies: progress and challenges. Transl Res 161(4): 293-306, Apr 2013.

Ramos Pedro, Casu Carla, Gardenghi Sara, Breda Laura, Crielaard Bart J, Guy Ella, Marongiu Maria Franca, Gupta Ritama, Levine Ross L, Abdel-Wahab Omar, Ebert Benjamin L, Van Rooijen Nico, Ghaffari Saghi, Grady Robert W, Giardina Patricia J, Rivella Stefano: Macrophages support pathological erythropoiesis in polycythemia vera and β-thalassemia. Nature medicine 19(4): 437-45, Apr 2013.

Dong Alisa, Rivella Stefano, Breda Laura: Gene therapy for hemoglobinopathies: progress and challenges. Translational research: the journal of laboratory and clinical medicine 161(4): 293-306, Apr 2013.

Zuccato Cristina, Breda Laura, Salvatori Francesca, Breveglieri Giulia, Gardenghi Sara, Bianchi Nicoletta, Brognara Eleonora, Lampronti Ilaria, Borgatti Monica, Rivella Stefano, Gambari Roberto: A combined approach for β-thalassemia based on gene therapy-mediated adult hemoglobin (HbA) production and fetal hemoglobin (HbF) induction. Annals of hematology 91(8): 1201-13, Aug 2012.

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Last updated: 07/03/2018
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