Kiran Musunuru, MD, PhD, MPH, ML
Professor of Medicine
Director, Penn Cardiovascular Institute's Genetic and Epigenetic Origins of Disease Program, Perelman School of Medicine at the University of Pennsylvania
Scientific Director, Penn Center for Inherited Cardiovascular Disease, Hospital of the University of Pennsylvania
Department: Medicine
Graduate Group Affiliations
Contact information
3400 Civic Center Blvd, Bldg 421
11-104 Smilow Center for Translational Research
Philadelphia, PA 19104
11-104 Smilow Center for Translational Research
Philadelphia, PA 19104
Office: 215-573-4717
Email:
kiranmusunuru@gmail.com
kiranmusunuru@gmail.com
Education:
AB (Biochemical Sciences)
Harvard College, Cambridge, MA, 1997.
PhD (Biomedical Sciences)
The Rockefeller University, New York, NY, 2003.
MD (Medicine)
Weill-Cornell Medical College, New York, NY, 2004.
MPH (Epidemiology)
Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, 2009.
ML (Law)
University of Pennsylvania Law School, Philadelphia, PA, 2019.
Permanent linkAB (Biochemical Sciences)
Harvard College, Cambridge, MA, 1997.
PhD (Biomedical Sciences)
The Rockefeller University, New York, NY, 2003.
MD (Medicine)
Weill-Cornell Medical College, New York, NY, 2004.
MPH (Epidemiology)
Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, 2009.
ML (Law)
University of Pennsylvania Law School, Philadelphia, PA, 2019.
Selected Publications
Musunuru K.: An overview of genome editing in cardiovascular and metabolic diseases. Adv Exp Med Biol 2023.Musunuru K.: CRISPR and cardiovascular diseases. Cardiovasc Res Apr 2022.
Whittaker MN, Musunuru K.: Therapeutic application of genome editing in dyslipidemia. Curr Opin Lipidol 33: 133-138, Apr 2022.
Yang Q, Hinkle J, Reed JN, Aherrahrou R, Xu Z, Harris TE, Stephenson EJ, Musunuru K, Keller SR, Civelek M.: Adipocyte-specific modulation of KLF14 expression in mice leads to sex-dependent impacts on adiposity and lipid metabolism. Diabetes 71: 677-693, Apr 2022.
Demissei BG, Lv W, Wilcox NS, Sheline K, Smith AM, Sturgeon KM, McDermott-Roe C, Musunuru K, Lefebvre B, Domchek SM, Shah P, Ky B.: BRCA1/2 mutations and cardiovascular function in breast cancer survivors. Front Cardiovasc Med 9: 833171, Feb 2022.
Banskota S, Raguram A, Suh S, Du SW, Davis JR, Choi EH, Wang X, Nielsen SC, Newby GA, Randolph PB, Osborn MJ, Musunuru K, Palczewski K, Liu DR.: Engineered virus-like particles for efficient in vivo delivery of therapeutic proteins. Cell 185: 250-265, Jan 2022.
Musunuru K.: Moving toward genome-editing therapies for cardiovascular diseases. J Clin Invest 132: e148555, Jan 2022.
Davis JR, Wang X, Witte IP, Huang TP, Levy JM, Raguram A, Banskota S, Seidah NG, Musunuru K, Liu DR.: Efficient in vivo base editing via single adeno-associated viruses with size-optimized genomes encoding compact adenine base editors. Nat Biomed Eng 2022.
Brooks DL, Musunuru K.: Detoxifying chemotherapy with genetics-guided stem cell modeling: A personalized affair. Cell Stem Cell 28: 2039-2040, Dec 2021.
Bose SK, White BM, Kashyap MV, Dave A, De Bie FR, Li H, Singh K, Menon P, Wang T, Teerdhala S, Swaminathan V, Hartman HA, Jayachandran S, Chandrasekaran P, Musunuru K, Jain R, Frank DB, Zoltick P, Peranteau WH.: In utero adenine base editing corrects multi-organ pathology in a lethal lysosomal storage disease. Nat Commun 12: 4291, Jul 2021.